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Clinical/translational cancer immunotherapy
Original research
Circulating T cell status and molecular imaging may predict clinical benefit of neoadjuvant PD-1 blockade in oral cancer

Authors

  • Niels E Wondergem Amsterdam UMC location Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Iris H C Miedema Amsterdam UMC location Vrije Universiteit Amsterdam, Medical Oncology, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Rieneke van de Ven Amsterdam UMC location Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The NetherlandsAmsterdam Institute for Infection and Immunity, Cancer Immunology, Amsterdam, Netherlands PubMed articlesGoogle scholar articles
  • Gerben J C Zwezerijnen Cancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The NetherlandsAmsterdam UMC location Vrije Universiteit Amsterdam, Radiology and Nuclear Medicine, De Boelelaan 1117, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Pim de Graaf Cancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The NetherlandsAmsterdam UMC location Vrije Universiteit Amsterdam, Radiology and Nuclear Medicine, De Boelelaan 1117, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • K Hakki Karagozoglu Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Oral and Maxillofacial Surgery/Oral Pathology, De Boelelaan 1117, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Jan-Jaap Hendrickx Amsterdam UMC location Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Simone E J Eerenstein Amsterdam UMC location Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Rolf J Bun Oral and Maxillofacial Surgery, Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands PubMed articlesGoogle scholar articles
  • Dorien C Mulder Oral and Maxillofacial Surgery, Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands PubMed articlesGoogle scholar articles
  • Jens Voortman Amsterdam UMC location Vrije Universiteit Amsterdam, Medical Oncology, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Ronald Boellaard Cancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The NetherlandsAmsterdam UMC location Vrije Universiteit Amsterdam, Radiology and Nuclear Medicine, De Boelelaan 1117, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Albert D Windhorst Cancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The NetherlandsAmsterdam UMC location Vrije Universiteit Amsterdam, Radiology and Nuclear Medicine, De Boelelaan 1117, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • J Pascal Hagers Amsterdam UMC location Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Laura A N Peferoen Amsterdam UMC location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Tanja D de Gruijl Amsterdam UMC location Vrije Universiteit Amsterdam, Medical Oncology, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Elisabeth Bloemena Amsterdam UMC location Vrije Universiteit Amsterdam, Pathology, De Boelelaan 1117, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Ruud H Brakenhoff Amsterdam UMC location Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • C René Leemans Amsterdam UMC location Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • C Willemien Menke-van der Houven van Oordt Amsterdam UMC location Vrije Universiteit Amsterdam, Medical Oncology, De Boelelaan 1117, Amsterdam, The NetherlandsCancer Center Amsterdam, Imaging and Biomarkers, Cancer Centre Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles

Citation

Wondergem NE, Miedema IHC, van de Ven R, et al
Circulating T cell status and molecular imaging may predict clinical benefit of neoadjuvant PD-1 blockade in oral cancer
Journal for ImmunoTherapy of Cancer 2024;12:e009278. doi: 10.1136/jitc-2024-009278
Online issue publication 
July 22, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.