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Basic tumor immunology
Original research
Tetracyclines enhance antitumor T-cell immunity via the Zap70 signaling pathway

Authors

  • Mari Tone Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Osaka, JapanDepartment of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles
  • Kota Iwahori Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Osaka, JapanDepartment of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles
  • Michinari Hirata Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Osaka, JapanBiopharmaceutical Research Division, Shionogi & Co., Ltd, Osaka, Japan PubMed articlesGoogle scholar articles
  • Azumi Ueyama Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Osaka, JapanBiopharmaceutical Research Division, Shionogi & Co., Ltd, Osaka, Japan PubMed articlesGoogle scholar articles
  • Akiyoshi Tani Compound Library Screening Center, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles
  • Jun-Ichi Haruta Lead Explorating Units, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles
  • Yoshito Takeda Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles
  • Yasushi Shintani Department of General Thoracic Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles
  • Atsushi Kumanogoh Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka, JapanDepartment of Immunopathology, World Premier International Research Center Initiative (WPI), Immunology Frontier Research Center (IFReC), Osaka University, Osaka, JapanIntegrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Osaka, JapanCenter for Infectious Diseases for Education and Research (CiDER), Osaka University, Osaka, JapanJapan Agency for Medical Research and Development – Core Research for Evolutional Science and Technology (AMED–CREST), Osaka University, Osaka, JapanCenter for Advanced Modalities and DDS (CAMaD), Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles
  • Hisashi Wada Department of Clinical Research in Tumor Immunology, Graduate School of Medicine, Osaka University, Osaka, Japan PubMed articlesGoogle scholar articles

Citation

Tone M, Iwahori K, Hirata M, et al
Tetracyclines enhance antitumor T-cell immunity via the Zap70 signaling pathway
Journal for ImmunoTherapy of Cancer 2024;12:e008334. doi: 10.1136/jitc-2023-008334
Online issue publication 
April 15, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.