Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis

Cathrin L C Gudd; Eoin Mitchell; Stephen R Atkinson; Marie-Anne Mawhin; Samra Turajlic; James Larkin; Mark R Thursz; Robert D Goldin; Nick Powell; Charalambos G Antoniades; Kevin J Woollard; Lucia A Possamai; Evangelos Triantafyllou

doi:10.1136/jitc-2023-008078

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Clinical/translational cancer immunotherapy

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Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis

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Cathrin L C Gudd Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Eoin Mitchell Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Stephen R Atkinson Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Marie-Anne Mawhin Centre for Inflammatory Disease, Imperial College London, London, UK PubMed articles Google scholar articles
Samra Turajlic Cancer Dynamics Laboratory, The Francis Crick Institute, London, UKRenal and Skin Units, The Royal Marsden NHS Foundation Trust, London, UKMelanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK PubMed articles Google scholar articles
James Larkin Renal and Skin Units, The Royal Marsden NHS Foundation Trust, London, UKMelanoma and Kidney Cancer Team, The Institute of Cancer Research, London, UK PubMed articles Google scholar articles
Mark R Thursz Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Robert D Goldin Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Nick Powell Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Charalambos G Antoniades Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Kevin J Woollard Centre for Inflammatory Disease, Imperial College London, London, UK PubMed articles Google scholar articles
Lucia A Possamai Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Evangelos Triantafyllou Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles

Citation

Gudd CLC, Mitchell E, Atkinson SR, et al

Therapeutic inhibition of monocyte recruitment prevents checkpoint inhibitor-induced hepatitis

Journal for ImmunoTherapy of Cancer 2024;12:e008078. doi: 10.1136/jitc-2023-008078

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April 04, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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