Defining D-irAEs: consensus-based disease definitions for the diagnosis of dermatologic adverse events from immune checkpoint inhibitor therapy

Steven T Chen; Yevgeniy R Semenov; Allireza Alloo; Daniel Q Bach; Allison Betof Warner; Amina Bougrine; Leeann Burton; Laura C Cappelli; Mariana Castells; Justine Cohen; Anna K Dewan; Riley Fadden; Lauren Guggina; Aparna Hegde; Victor Huang; Douglas B Johnson; Benjamin Kaffenberger; Daniela Kroshinsky; Shawn Kwatra; Bernice Kwong; Mario E Lacouture; Cecilia Larocca; Jonathan Leventhal; Alina Markova; Jon McDunn; Meghan J Mooradian; Jarushka Naidoo; Jennifer Choi; Vinod Nambudiri; Caroline A Nelson; Anisha B Patel; Julia Pimkina; Johnathan Rine; Krista M Rubin; Maxwell Sauder; Sheila Shaigany; Afreen Shariff; Ryan J Sullivan; Leyre Zubiri; Kerry L Reynolds; Nicole R LeBoeuf

doi:10.1136/jitc-2023-007675

Article info

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Defining D-irAEs: consensus-based disease definitions for the diagnosis of dermatologic adverse events from immune checkpoint inhibitor therapy

Authors

Steven T Chen Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA Mass General Cancer Center, Boston, MA, USA Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Yevgeniy R Semenov Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Allireza Alloo Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA PubMed articles Google scholar articles
Daniel Q Bach Department of Dermatology, Cedars Sinai, Los Angeles, California, USA PubMed articles Google scholar articles
Allison Betof Warner Memorial Sloan Kettering Cancer Center, New York, New York, USA PubMed articles Google scholar articles
Amina Bougrine Department of Dermatology, Université de Montréal, Montreal, Quebec, Canada PubMed articles Google scholar articles
Leeann Burton Biogen Inc, Cambridge, Massachusetts, USA PubMed articles Google scholar articles
Laura C Cappelli Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articles Google scholar articles
Mariana Castells Harvard Medical School, Boston, Massachusetts, USA Department of Medicine, Division of Allergy and Clinical Immunology, Brigham and Women's Hospital, Boston, Massachusetts, USA PubMed articles Google scholar articles
Justine Cohen Harvard Medical School, Boston, Massachusetts, USA Department of Medical Oncology, Centers for Cutaneous and Melanoma Oncology, Dana-Farber Cancer Insititute, Boston, MA, USA PubMed articles Google scholar articles
Anna K Dewan Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articles Google scholar articles
Riley Fadden Mass General Cancer Center, Boston, MA, USA PubMed articles Google scholar articles
Lauren Guggina Harvard Medical School, Boston, Massachusetts, USA Department of Dermatology, Brigham and Women’s Hospital, Boston, Massachusetts, USA Center for Cutaneous Oncology, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Aparna Hegde UAB, Birmingham, Alabama, USA PubMed articles Google scholar articles
Victor Huang Department of Dermatology, University of California Davis, Davis, California, USA PubMed articles Google scholar articles
Douglas B Johnson Vanderbilt University Medical Center, Nashville, Tennessee, USA PubMed articles Google scholar articles
Benjamin Kaffenberger Department of Dermatology, Ohio State University Wexner Medical Center, Columbus, Ohio, USA PubMed articles Google scholar articles
Daniela Kroshinsky Department of Dermatology, Duke University Medical Center, Durham, North Carolina, USA PubMed articles Google scholar articles
Shawn Kwatra Johns Hopkins Department of Dermatology, Baltimore, Maryland, USA PubMed articles Google scholar articles
Bernice Kwong Stanford University School of Medicine, Stanford, UK PubMed articles Google scholar articles
Mario E Lacouture MSKCC, New York, New York, USA NYU Langone Health, New York, New York, USA PubMed articles Google scholar articles
Cecilia Larocca Harvard Medical School, Boston, Massachusetts, USA Department of Dermatology, Brigham and Women’s Hospital, Boston, Massachusetts, USA Center for Cutaneous Oncology, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Jonathan Leventhal Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA PubMed articles Google scholar articles
Alina Markova Memorial Sloan Kettering Cancer Center, New York, New York, USA PubMed articles Google scholar articles
Jon McDunn Project Data Sphere ®, Morrisville, North Carolina, USA PubMed articles Google scholar articles
Meghan J Mooradian Mass General Cancer Center, Boston, MA, USA Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
Jarushka Naidoo Johns Hopkins University, The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland, USA PubMed articles Google scholar articles
Jennifer Choi Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA PubMed articles Google scholar articles
Vinod Nambudiri Harvard Medical School, Boston, Massachusetts, USA Department of Dermatology, Brigham and Women’s Hospital, Boston, Massachusetts, USA Center for Cutaneous Oncology, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Caroline A Nelson Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA PubMed articles Google scholar articles
Anisha B Patel Department of Dermatology, Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Julia Pimkina Harvard Medical School, Boston, Massachusetts, USA Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA PubMed articles Google scholar articles
Johnathan Rine Project Data Sphere ®, Morrisville, North Carolina, USA PubMed articles Google scholar articles
Krista M Rubin Mass General Cancer Center, Boston, MA, USA PubMed articles Google scholar articles
Maxwell Sauder DIvision of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada Princess Margaret Cancer Centre, Toronto, Ontario, Canada PubMed articles Google scholar articles
Sheila Shaigany Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA PubMed articles Google scholar articles
Afreen Shariff Department of Medicine, Duke University School of Medicine, Durham, NC, USA PubMed articles Google scholar articles
Ryan J Sullivan Mass General Cancer Center, Boston, MA, USA Harvard Medical School, Boston, Massachusetts, USA Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articles Google scholar articles
Leyre Zubiri Mass General Cancer Center, Boston, MA, USA Harvard Medical School, Boston, Massachusetts, USA Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articles Google scholar articles
Kerry L Reynolds Mass General Cancer Center, Boston, MA, USA Harvard Medical School, Boston, Massachusetts, USA Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articles Google scholar articles
Nicole R LeBoeuf Harvard Medical School, Boston, Massachusetts, USA Department of Dermatology, Brigham and Women’s Hospital, Boston, Massachusetts, USA Center for Cutaneous Oncology, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles

Citation

Chen ST, Semenov YR, Alloo A, et al

Defining D-irAEs: consensus-based disease definitions for the diagnosis of dermatologic adverse events from immune checkpoint inhibitor therapy

Journal for ImmunoTherapy of Cancer 2024;12:e007675. doi: 10.1136/jitc-2023-007675

Online issue publication

April 10, 2024

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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