862 TLR9 agonism promotes cytotoxic T cell persistence and myeloid remodeling when combined with radiation therapy and PD-1 blockade in oligometastatic prostate cancer patients

Zenghua Fan; David Y Oh; Anthony Wong; Katsuto Shinohara; Hao Nguyen; Caleb Hwang; Hewitt Chang; Alec Starzinski; Tony Li; Christopher De Leon; Marissa Gin; Eliezer Van Allen; Li Zhang; Rahul R Aggarwal; Terence W Friedlander; Eric J Small; Felix Y Feng; Lawrence Fong

doi:10.1136/jitc-2023-SITC2023.0862

Article info

Regular and Young Investigator Award Abstracts

Combination Immunotherapies

862 TLR9 agonism promotes cytotoxic T cell persistence and myeloid remodeling when combined with radiation therapy and PD-1 blockade in oligometastatic prostate cancer patients

Authors

Zenghua Fan University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
David Y Oh University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Anthony Wong University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Katsuto Shinohara University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Hao Nguyen University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Caleb Hwang University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Hewitt Chang University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Alec Starzinski University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Tony Li University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Christopher De Leon University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Marissa Gin University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Eliezer Van Allen Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Li Zhang University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Rahul R Aggarwal University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Terence W Friedlander University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Eric J Small University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Felix Y Feng University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Lawrence Fong University of California, San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles

Citation

Fan Z, Oh DY, Wong A, et al

862 TLR9 agonism promotes cytotoxic T cell persistence and myeloid remodeling when combined with radiation therapy and PD-1 blockade in oligometastatic prostate cancer patients

Journal for ImmunoTherapy of Cancer 2023;11:doi: 10.1136/jitc-2023-SITC2023.0862

Online issue publication

November 02, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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