578 Anti-PD-1 therapy alters the generation and durability of de novo responses to vaccination in humans

Kelly P Burke; Taras M Chicz; Joanna Baginska; Julia Huezo; Marta Holovatska; Michael Manos; Duck Kyun Yoo; Fnu Keerti; Caihong Bi; Ryan McNamara; Duane Wesemann; F Stephen Hodi; Elizabeth I Buchbinder; Arlene Sharpe

doi:10.1136/jitc-2023-SITC2023.0578

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Regular and Young Investigator Award Abstracts

Checkpoint Blockade Therapy

578 Anti-PD-1 therapy alters the generation and durability of de novo responses to vaccination in humans

Authors

Kelly P Burke Dana-Farber Cancer Institute, Boston, MA, USA Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Taras M Chicz Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA PubMed articles Google scholar articles
Joanna Baginska Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Julia Huezo Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Marta Holovatska Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Michael Manos Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Duck Kyun Yoo Brigham and Women’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Fnu Keerti Brigham and Women’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Caihong Bi Brigham and Women’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Ryan McNamara Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA PubMed articles Google scholar articles
Duane Wesemann Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA Brigham and Women’s Hospital, Boston, MA, USA Broad Institute, Cambridge, MA, USA PubMed articles Google scholar articles
F Stephen Hodi Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Elizabeth I Buchbinder Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Arlene Sharpe Broad Institute, Cambridge, MA, USA Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles

Citation

Burke KP, Chicz TM, Baginska J, et al

578 Anti-PD-1 therapy alters the generation and durability of de novo responses to vaccination in humans

Journal for ImmunoTherapy of Cancer 2023;11:doi: 10.1136/jitc-2023-SITC2023.0578

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November 02, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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