277 SynNotch-CAR T cells demonstrate potent anti-tumor efficacy in a preclinical immunocompetent mouse model for glioblastoma

Senthilnath Lakshmanachetty; Milos Simic; Payal Watchmaker; Akane Yamamichi; Tiffany Chen; Su Phyu; Takahide Nejo; Chanelle Shepherd; Jason Duecker; Yuan Wang; Olga Troyanskaya; Lia Cardarelli; Sachdev Sidhu; Wendell Lim; Hideho Okada

doi:10.1136/jitc-2023-SITC2023.0277

Article info

Regular and Young Investigator Award Abstracts

Cellular Therapies

277 SynNotch-CAR T cells demonstrate potent anti-tumor efficacy in a preclinical immunocompetent mouse model for glioblastoma

Authors

Senthilnath Lakshmanachetty University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Milos Simic University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Payal Watchmaker University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Akane Yamamichi University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Tiffany Chen University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Su Phyu University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Takahide Nejo University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Chanelle Shepherd University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Jason Duecker University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Yuan Wang Princeton University, Princeton, NJ, USA PubMed articles Google scholar articles
Olga Troyanskaya Princeton University, Princeton, NJ, USA PubMed articles Google scholar articles
Lia Cardarelli University of Toronto, Toronto, ON, Canada PubMed articles Google scholar articles
Sachdev Sidhu University of Toronto, Toronto, ON, Canada PubMed articles Google scholar articles
Wendell Lim University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles
Hideho Okada University of California San Francisco, San Francisco, CA, USA PubMed articles Google scholar articles

Citation

Lakshmanachetty S, Simic M, Watchmaker P, et al

277 SynNotch-CAR T cells demonstrate potent anti-tumor efficacy in a preclinical immunocompetent mouse model for glioblastoma

Journal for ImmunoTherapy of Cancer 2023;11:doi: 10.1136/jitc-2023-SITC2023.0277

Online issue publication

November 02, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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