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  • 1393 Discovery of PLX-4107, a selective IKZF2 molecular glue degrader, that modulates suppressive regulatory T cells and demonstrates anti-tumor activity

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Regular and Young Investigator Award Abstracts
Novel Single-Agent Immunotherapies
1393 Discovery of PLX-4107, a selective IKZF2 molecular glue degrader, that modulates suppressive regulatory T cells and demonstrates anti-tumor activity

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Thompson PA, Yang P, Huang Y, et al
1393 Discovery of PLX-4107, a selective IKZF2 molecular glue degrader, that modulates suppressive regulatory T cells and demonstrates anti-tumor activity
Journal for ImmunoTherapy of Cancer 2023;11:doi: 10.1136/jitc-2023-SITC2023.1393