1245 Th17 and Type 2 CD8+ cytokine signatures predict irAEs in solid tumors

Chester J Kao; Soren Charmsaz; Madalena Brancati; Stephanie L Alden; Howard L Li; Aanika Balaji; Kabeer Munjal; Hua-Ling Tsai; Ludmila Danilova; Alexei Hernandez; Nicole Gross; Erin M Coyne; Sarah M Shin; Jennifer Durham; Brian Christmas; Christopher Thoburn; Maximilian F Konig; Evan J Lipson; Jarushka Naidoo; Laura Cappelli; Yasser Ged; Marina Barretti; Julie Brahmer; Jean Hoffman-Censits; Tanguy Y Seiwert; Rachel Garonce-Hediger; Sanjay Bansal; Laura Tang; Elizabeth M Jaffee; G Scott Chandler; Rajat Mohindra; Won Jin Ho; Mark Yarchoan

doi:10.1136/jitc-2023-SITC2023.1245

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Regular and Young Investigator Award Abstracts

Immunotherapy Toxicities

1245 Th17 and Type 2 CD8+ cytokine signatures predict irAEs in solid tumors

Authors

Chester J Kao Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Soren Charmsaz Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Madalena Brancati Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Stephanie L Alden Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Howard L Li Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Aanika Balaji Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Kabeer Munjal Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Hua-Ling Tsai Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Ludmila Danilova Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Alexei Hernandez Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Nicole Gross Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Erin M Coyne Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Sarah M Shin Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Jennifer Durham Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Brian Christmas Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Christopher Thoburn Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Maximilian F Konig Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Evan J Lipson The Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, MD, USA PubMed articles Google scholar articles
Jarushka Naidoo Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Laura Cappelli Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Yasser Ged Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Marina Barretti Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Julie Brahmer Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Jean Hoffman-Censits Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Tanguy Y Seiwert Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Rachel Garonce-Hediger F. Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Sanjay Bansal Genentech, Pearland, TX, USA PubMed articles Google scholar articles
Laura Tang Genentech, Hoboken, NJ, USA PubMed articles Google scholar articles
Elizabeth M Jaffee Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
G Scott Chandler Genentech/Roche, Basel, Switzerland PubMed articles Google scholar articles
Rajat Mohindra F.Hoffmann-La Roche Ltd, Basel, Switzerland PubMed articles Google scholar articles
Won Jin Ho Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles
Mark Yarchoan Johns Hopkins University School of Medicine, Baltimore, MD, USA PubMed articles Google scholar articles

Citation

Kao CJ, Charmsaz S, Brancati M, et al

1245 Th17 and Type 2 CD8+ cytokine signatures predict irAEs in solid tumors

Journal for ImmunoTherapy of Cancer 2023;11:doi: 10.1136/jitc-2023-SITC2023.1245

Online issue publication

November 02, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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