1111 Targeting lipid metabolism to improve PARP inhibitor response in BRCA-associated TNBC

Carlos Wagner Wanderley; Daniel E Michaud; Kiran Kurmi; Adam Nelson; Kelly F Zheng; Shakchhi Joshi; Anita Mehta; Madeline G Townsend; Filipa Lynce; Geoffrey I Shapiro; Jessica Thaxton; Marcia Haigis; Jennifer L Guerriero

doi:10.1136/jitc-2023-SITC2023.1111

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Regular and Young Investigator Award Abstracts

Immune-Stimulants and Immune Modulators

1111 Targeting lipid metabolism to improve PARP inhibitor response in BRCA-associated TNBC

Authors

Carlos Wagner Wanderley Brigham and Women’s Hospital, Alston, MA, USA PubMed articles Google scholar articles
Daniel E Michaud Brigham and Women’s Hospital, Brookline, MA, USA Department of Surgery, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Kiran Kurmi Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Adam Nelson Brigham and Women’s Hospital, Brookline, MA, USA Brigham and Women’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Kelly F Zheng Department of Surgery, Harvard Medical School, Boston, MA, USA Breast Oncology Program, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Shakchhi Joshi Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Anita Mehta Brigham and Women’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Madeline G Townsend Department of Surgery, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Filipa Lynce Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Geoffrey I Shapiro Dana-Farber Cancer Institute, Boston, MA, USA Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA PubMed articles Google scholar articles
Jessica Thaxton Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Marcia Haigis Brigham and Women’s Hospital, Boston, MA, USA Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Jennifer L Guerriero Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA PubMed articles Google scholar articles

Citation

Wanderley CW, Michaud DE, Kurmi K, et al

1111 Targeting lipid metabolism to improve PARP inhibitor response in BRCA-associated TNBC

Journal for ImmunoTherapy of Cancer 2023;11:doi: 10.1136/jitc-2023-SITC2023.1111

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November 02, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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