982 Immune mediated mechanisms of PARPi resistance in BRCA1-associated triple negative breast cancer (TNBC)

Adam Nelson; Anita Mehta; Madeline G Townsend; Madisson Oliwa; Kelly F Zheng; Patrice A Lee; Nicholas A Saccomano; Filipa Lynce; Nabihah Tayob; Geoffrey I Shapiro; Jennifer L Guerriero

doi:10.1136/jitc-2023-SITC2023.0982

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Regular and Young Investigator Award Abstracts

Immune Cell Types and Biology

982 Immune mediated mechanisms of PARPi resistance in BRCA1-associated triple negative breast cancer (TNBC)

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Adam Nelson Brigham and Woman’s Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles
Anita Mehta Harvard Medical School, Boston, MA, USA Division of Breast Surgery, Department of Surgery, Brigham and Women’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Madeline G Townsend Brigham and Woman’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Madisson Oliwa Division of Breast Surgery, Department of Surgery, Brigham and Women’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Kelly F Zheng Brigham and Woman’s Hospital, Boston, MA, USA PubMed articles Google scholar articles
Patrice A Lee Pfizer, Boulder, CO, USA PubMed articles Google scholar articles
Nicholas A Saccomano Pfizer, Boulder, CO, USA PubMed articles Google scholar articles
Filipa Lynce Harvard Medical School, Boston, MA, USA Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Nabihah Tayob Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Geoffrey I Shapiro Harvard Medical School, Boston, MA, USA Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA PubMed articles Google scholar articles
Jennifer L Guerriero Brigham and Woman’s Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA Ludwig Center for Cancer Research at Harvard, Harvard Medical School, Boston, MA, USA Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA, USA PubMed articles Google scholar articles

Citation

Nelson A, Mehta A, Townsend MG, et al

982 Immune mediated mechanisms of PARPi resistance in BRCA1-associated triple negative breast cancer (TNBC)

Journal for ImmunoTherapy of Cancer 2023;11:doi: 10.1136/jitc-2023-SITC2023.0982

Online issue publication

November 02, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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