You are here

Article info

Article menu
Oncolytic and local immunotherapy
Original research
Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1

Authors

  • Huy-Dung Hoang Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Aida Said Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Nasana Vaidya Department Immunology, University of Toronto, Toronto, Ontario, Canada PubMed articlesGoogle scholar articles
  • Victoria H Gilchrist Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Kyle Malone Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Usha Kabilan Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Serena Topshee Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Xiao Xiang Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • An-Dao Yang Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • David Olagnier Department of Biomedicine, Aarhus University, Aarhus, Denmark PubMed articlesGoogle scholar articles
  • Karen Mossman Department of Medicine, McMaster University, Hamilton, Ontario, Canada PubMed articlesGoogle scholar articles
  • Shawn T Beug Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Seyed Mehdi Jafarnejad Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK PubMed articlesGoogle scholar articles
  • Samuel T Workenhe Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada PubMed articlesGoogle scholar articles
  • Tyson E Graber Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Tommy Alain Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, CanadaDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaCentre for Infection, Immunity and Inflammation, University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles

Citation

Hoang H, Said A, Vaidya N, et al
Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1
Journal for ImmunoTherapy of Cancer 2023;11:e006408. doi: 10.1136/jitc-2022-006408
Online issue publication 
October 18, 2023

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.