Single-cell spatial landscape of immunotherapy response reveals mechanisms of CXCL13 enhanced antitumor immunity

Mark Sorin; Elham Karimi; Morteza Rezanejad; Miranda W Yu; Lysanne Desharnais; Sheri A C McDowell; Samuel Doré; Azadeh Arabzadeh; Valerie Breton; Benoit Fiset; Yuhong Wei; Roni Rayes; Michele Orain; Francois Coulombe; Venkata S K Manem; Andreanne Gagne; Daniela F Quail; Philippe Joubert; Jonathan D Spicer; Logan A Walsh

doi:10.1136/jitc-2022-005545

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Immunotherapy biomarkers

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Single-cell spatial landscape of immunotherapy response reveals mechanisms of CXCL13 enhanced antitumor immunity

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Mark Sorin Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Elham Karimi Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Morteza Rezanejad Department of Psychology and Computer Science, University of Toronto, Toronto, Ontario, Canada PubMed articles Google scholar articles
Miranda W Yu Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Physiology, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Lysanne Desharnais Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Sheri A C McDowell Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Physiology, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Samuel Doré Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Azadeh Arabzadeh Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Valerie Breton Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Benoit Fiset Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Yuhong Wei Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Roni Rayes Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Michele Orain Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec City, Quebec, Canada PubMed articles Google scholar articles
Francois Coulombe Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec City, Quebec, Canada PubMed articles Google scholar articles
Venkata S K Manem Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec City, Quebec, Canada PubMed articles Google scholar articles
Andreanne Gagne Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec City, Quebec, Canada PubMed articles Google scholar articles
Daniela F Quail Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Physiology, McGill University, Montreal, Quebec, CanadaDepartment of Medicine, Division of Experimental Medicine, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Philippe Joubert Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec City, Quebec, Canada PubMed articles Google scholar articles
Jonathan D Spicer Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Surgery, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles
Logan A Walsh Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Quebec, CanadaDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada PubMed articles Google scholar articles

Citation

Sorin M, Karimi E, Rezanejad M, et al

Single-cell spatial landscape of immunotherapy response reveals mechanisms of CXCL13 enhanced antitumor immunity

Journal for ImmunoTherapy of Cancer 2023;11:e005545. doi: 10.1136/jitc-2022-005545

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October 18, 2023

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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