Oral beclomethasone dipropionate is an effective treatment for immune checkpoint inhibitor induced colitis

James L Alexander; Hajir Ibraheim; Camellia Richards; Ben Shum; Polychronis Pavlidis; Nikki Hunter; Julian P Teare; Andrew Wotherspoon; Andrew Furness; Samra Turajlic; Lisa Pickering; James Larkin; Ally Speight; Sophie Papa; Nick Powell

doi:10.1136/jitc-2022-005490

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Clinical/translational cancer immunotherapy

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Oral beclomethasone dipropionate is an effective treatment for immune checkpoint inhibitor induced colitis

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James L Alexander Department of Gastroenterology, Royal Marsden NHS Foundation Trust, London, UKDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Hajir Ibraheim Department of Gastroenterology, Royal Marsden NHS Foundation Trust, London, UKDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Camellia Richards Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Ben Shum Renal & Skin Units, Royal Marsden NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Polychronis Pavlidis Experimental Immunobiology, King's College London, London, UKDepartment of Gastroenterology, King's College Hospital NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Nikki Hunter Renal & Skin Units, Royal Marsden NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Julian P Teare Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles
Andrew Wotherspoon Department of Histopathology, Royal Marsden NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Andrew Furness Renal & Skin Units, Royal Marsden NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Samra Turajlic Renal & Skin Units, Royal Marsden NHS Foundation Trust, London, UKCancer Dynamics Laboratory, The Francis Crick Institute, London, UK PubMed articles Google scholar articles
Lisa Pickering Renal & Skin Units, Royal Marsden NHS Foundation Trust, London, UK PubMed articles Google scholar articles
James Larkin Renal & Skin Units, Royal Marsden NHS Foundation Trust, London, UK PubMed articles Google scholar articles
Ally Speight Department of Gastroenterology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK PubMed articles Google scholar articles
Sophie Papa School of Cancer and Pharmaceutical Sciences, King's College London, London, UK PubMed articles Google scholar articles
Nick Powell Department of Gastroenterology, Royal Marsden NHS Foundation Trust, London, UKDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articles Google scholar articles

Citation

Alexander JL, Ibraheim H, Richards C, et al

Oral beclomethasone dipropionate is an effective treatment for immune checkpoint inhibitor induced colitis

Journal for ImmunoTherapy of Cancer 2022;10:e005490. doi: 10.1136/jitc-2022-005490

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September 16, 2022

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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