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  • LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization

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Basic tumor immunology
Original research
LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization

Authors

  • Jinyang Hu Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, ChinaDepartment of Neurosurgery, The First People’s Hospital of Yichang, China Three Gorges University People's Hospital, Yichang, Hubei, China PubMed articlesGoogle scholar articles
  • Feng Dong State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Cancer Institute and Hospital, Department of Cell Biology, Tianjin Medical University, Tianjin, ChinaDepartment of Neurosurgery, Laboratory of Neuro-Oncology, Tianjin Medical University General Hospital, Tianjin, China PubMed articlesGoogle scholar articles
  • You He State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Cancer Institute and Hospital, Department of Cell Biology, Tianjin Medical University, Tianjin, China PubMed articlesGoogle scholar articles
  • Xianyou Xia State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Cancer Institute and Hospital, Department of Cell Biology, Tianjin Medical University, Tianjin, China PubMed articlesGoogle scholar articles
  • Fangling Cheng Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Sui Chen Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Xiaoshuang Hou Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Po Zhang Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Guohao Liu Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Ying Li Experimental Medicine Center, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical Colleg, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Qian Gao Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology, Beijing, ChinaCentral Laboratory, Peking University School of Stomatology, Beijing, China PubMed articlesGoogle scholar articles
  • Minhai Dong Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Ting Li State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Cancer Institute and Hospital, Department of Cell Biology, Tianjin Medical University, Tianjin, China PubMed articlesGoogle scholar articles
  • Wei Li Tianjin First Central Hospital, Tianjin, China PubMed articlesGoogle scholar articles
  • Qungen Xiao Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Xiaopeng Li Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Xingjiang Yu Department of Histology and Embryology, College of Basic Medicine, Huazhong University of Science and Technology, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Guifa Xi Northwestern University Feinberg School of Medicine, Chicago, Illinois, USAAbbott Molecular Inc, Des Plaines, Illinois, USA PubMed articlesGoogle scholar articles
  • Dongsheng Guo Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles
  • Xudong Wu State Key Laboratory of Experimental Hematology, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Cancer Institute and Hospital, Department of Cell Biology, Tianjin Medical University, Tianjin, ChinaDepartment of Neurosurgery, Laboratory of Neuro-Oncology, Tianjin Medical University General Hospital, Tianjin, China PubMed articlesGoogle scholar articles
  • Baofeng Wang Department of Neurosurgery, Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College, Wuhan, Hubei, China PubMed articlesGoogle scholar articles

Citation

Hu J, Dong F, He Y, et al
LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization
Journal for ImmunoTherapy of Cancer 2022;10:e004452. doi: 10.1136/jitc-2021-004452
Online issue publication 
September 12, 2022

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.