BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma

Mirela Kremenovic; Alfred A Chan; Bing Feng; Lukas Bäriswyl; Steve Robatel; Thomas Gruber; Li Tang; Delphine J Lee; Mirjam Schenk

doi:10.1136/jitc-2021-004133

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Oncolytic and local immunotherapy

Original research

BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma

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Mirela Kremenovic Experimental Pathology, University of Bern Institute of Pathology, Bern, SwitzerlandGraduate School Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland PubMed articles Google scholar articles
Alfred A Chan Division of Dermatology, Department of Medicine, The Lundquist Institute, Torrance, California, USA PubMed articles Google scholar articles
Bing Feng Institute of Bioengineering and Institute of Materials Science and Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, VD, Switzerland PubMed articles Google scholar articles
Lukas Bäriswyl Experimental Pathology, University of Bern Institute of Pathology, Bern, Switzerland PubMed articles Google scholar articles
Steve Robatel Experimental Pathology, University of Bern Institute of Pathology, Bern, SwitzerlandGraduate School Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland PubMed articles Google scholar articles
Thomas Gruber Experimental Pathology, University of Bern Institute of Pathology, Bern, Switzerland PubMed articles Google scholar articles
Li Tang Institute of Bioengineering and Institute of Materials Science and Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, VD, Switzerland PubMed articles Google scholar articles
Delphine J Lee Division of Dermatology, Department of Medicine, The Lundquist Institute, Torrance, California, USA PubMed articles Google scholar articles
Mirjam Schenk Experimental Pathology, University of Bern Institute of Pathology, Bern, Switzerland PubMed articles Google scholar articles

Citation

Kremenovic M, Chan AA, Feng B, et al

BCG hydrogel promotes CTSS-mediated antigen processing and presentation, thereby suppressing metastasis and prolonging survival in melanoma

Journal for ImmunoTherapy of Cancer 2022;10:e004133. doi: 10.1136/jitc-2021-004133

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January 24, 2024

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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