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Oncolytic and local immunotherapy
Original research
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity

Authors

  • Beatrice Thier Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany PubMed articlesGoogle scholar articles
  • Fang Zhao Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany PubMed articlesGoogle scholar articles
  • Simone Stupia Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany PubMed articlesGoogle scholar articles
  • Alicia Brüggemann Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany PubMed articlesGoogle scholar articles
  • Johannes Koch Imaging Center Campus Essen, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany PubMed articlesGoogle scholar articles
  • Nina Schulze Imaging Center Campus Essen, Center of Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany PubMed articlesGoogle scholar articles
  • Susanne Horn Rudolf Schönheimer Institute of Biochemistry, University of Leipzig, Leipzig, Germany PubMed articlesGoogle scholar articles
  • Christoph Coch Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn, Bonn, GermanyNextevidence GmbH, Grünwald, Germany PubMed articlesGoogle scholar articles
  • Gunther Hartmann Institute of Clinical Chemistry and Clinical Pharmacology, University of Bonn, Bonn, Germany PubMed articlesGoogle scholar articles
  • Antje Sucker Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany PubMed articlesGoogle scholar articles
  • Dirk Schadendorf Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany PubMed articlesGoogle scholar articles
  • Annette Paschen Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, GermanyGerman Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany PubMed articlesGoogle scholar articles

Citation

Thier B, Zhao F, Stupia S, et al
Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity
Journal for ImmunoTherapy of Cancer 2022;10:e003863. doi: 10.1136/jitc-2021-003863
Online issue publication 
January 24, 2024

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Copyright information

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.