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  • The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation

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Clinical/translational cancer immunotherapy
The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation

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Sum E, Rapp M, Dürr H, et al
The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation
Journal for ImmunoTherapy of Cancer 2022;10:e003264. doi: 10.1136/jitc-2021-003264