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  • TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer

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Basic tumor immunology
Original research
TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer

Authors

  • Maria Perez-Penco National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Stine Emilie Weis-Banke National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Aimilia Schina National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Majken Siersbæk Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark PubMed articlesGoogle scholar articles
  • Mie Linder Hübbe National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Mia Aaboe Jørgensen National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Inés Lecoq National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, DenmarkIO Biotech ApS, Copenhagen, Denmark PubMed articlesGoogle scholar articles
  • Lucia Lara de la Torre National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Simone Kloch Bendtsen National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Evelina Martinenaite National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, DenmarkIO Biotech ApS, Copenhagen, Denmark PubMed articlesGoogle scholar articles
  • Morten Orebo Holmström National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Daniel Hargbøl Madsen National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, DenmarkDepartment of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark PubMed articlesGoogle scholar articles
  • Marco Donia National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark PubMed articlesGoogle scholar articles
  • Niels Ødum Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark PubMed articlesGoogle scholar articles
  • Lars Grøntved Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark PubMed articlesGoogle scholar articles
  • Mads Hald Andersen National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, DenmarkDepartment of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark PubMed articlesGoogle scholar articles

Citation

Perez-Penco M, Weis-Banke SE, Schina A, et al
TGFβ-derived immune modulatory vaccine: targeting the immunosuppressive and fibrotic tumor microenvironment in a murine model of pancreatic cancer
Journal for ImmunoTherapy of Cancer 2022;10:e005491. doi: 10.1136/jitc-2022-005491
Online issue publication 
October 18, 2023

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Copyright information

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.