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Immunotherapy biomarkers
Original research
Single-cell immune signature for detecting early-stage HCC and early assessing anti-PD-1 immunotherapy efficacy

Authors

  • Jiawei Shi Key Laboratory for Biomedical Engineering of the Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, People's Republic of ChinaDepartments of Cell Biology and Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Junwei Liu Key Laboratory for Biomedical Engineering of the Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, People's Republic of ChinaDepartment of Hepatobiliary and Pancreatic Surgery, The Center for Integrated Oncology and Precision Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Xiaoxuan Tu Department of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, & Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Bin Li Department of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, & Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Zhou Tong Department of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Tian Wang Zhejiang Puluoting Health Technology Co., Ltd, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Yi Zheng Department of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of ChinaZhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research, Zhejiang University, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Hongyu Shi Zhejiang Puluoting Health Technology Co., Ltd, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Xun Zeng State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Wei Chen Key Laboratory for Biomedical Engineering of the Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, People's Republic of ChinaDepartments of Cell Biology and Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of ChinaDepartment of Hepatobiliary and Pancreatic Surgery, The Center for Integrated Oncology and Precision Medicine, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Weiwei Yin Key Laboratory for Biomedical Engineering of the Ministry of Education, College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, People's Republic of ChinaDepartment of Thoracic Surgery, Zhejiang University School of Medicine, Sir Run Run Shaw Hospital, Hangzhou, People's Republic of ChinaZhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, College of Biomedical Engineering and Instrument of Science, Zhejiang University, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Weijia Fang Department of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, & Key Laboratory of Cancer Prevention and Intervention, Ministry of Education, Hangzhou, People's Republic of China PubMed articlesGoogle scholar articles

Citation

Shi J, Liu J, Tu X, et al
Single-cell immune signature for detecting early-stage HCC and early assessing anti-PD-1 immunotherapy efficacy
Journal for ImmunoTherapy of Cancer 2022;10:e003133. doi: 10.1136/jitc-2021-003133
Online issue publication 
October 18, 2023

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.