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1466 Galectin-1 orchestrates a hierarchical tumor to stromal extracellular vesicles system that fosters immune suppression
Camila A Bach, Ada Blidner, Ramiro Perrotta, Joaquin P Merlo, Mariana Salatino, Gabriel Rabinovich

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1630; DOI: 10.1136/jitc-2023-SITC2023.1466
1467 Selective targeting of integrins αVβ8 and αVβ1 within the dynamic ecosystem of pancreatic cancer to improve the overall anti-tumor response
Diego Chacon Fajardo, Chad L Moore, Sean Porazinski, Benjamin McLean, Eve Borbilas, Australian Pancreatic Cancer Genome Initiative, Vishal Kothari, Tim Machajewski, Fernando Rock, Scott M Turner, Marina Pajic

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1631; DOI: 10.1136/jitc-2023-SITC2023.1467
1469 Mesenchymal stem cells derived from cervical cancer promote M2 macrophage polarization
Víctor Cortes-Morales, Luis Chávez-Sánchez, Leticia Rocha-Zavaleta, Sandra Espíndola-Garibay, Alberto Monroy-García, Marta Elena Castro-Manrreza, Guadalupe Rosario Fajardo-Orduña, Teresa Apresa-García, Marcos Gutiérrez-de la Barrera, Héctor Mayani, Juan José Montesinos

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1633; DOI: 10.1136/jitc-2023-SITC2023.1469
1470 Precision immuno-oncology (IO) ISH/IF multiplex panel: spatial detection of cytokines and IO biomarkers
Brenna Dennison, Stephanie Allen, Bhavika Patel, Jacob Stapleton, Roni Archuleta, Mary Lou Rath, Sameer Talwalkar

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1634; DOI: 10.1136/jitc-2023-SITC2023.1470
1471 The role of cholesterol handling in gamma delta T cell cytotoxicity against highly immune suppressive pancreas ductal adenocarcinoma
Johnathan Ebben, David Turicek, Md Shahadat Hossan, Austin Stram, Ethan Lin, Nicholas J Hess, Zachary Mayhew, Melissa Kinney, Christian Capitini, Jeremy Kratz

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1635; DOI: 10.1136/jitc-2023-SITC2023.1471
1472 Targeting PDGFRb for superior bladder cancer treatment
Hajar El Ahandidi, Marine Leblond, Daniel Benamran, Petros Tsantoulis, Mohammed El mzibri, Mohammed Attaleb, Gregory Verdeil, Camilla Jandus

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1636; DOI: 10.1136/jitc-2023-SITC2023.1472
1473 Prostaglandin E2 and the tumor microenvironment: unleashing the potential of cancer immunotherapy through rational combination therapies
Anais Elewaut, Guillem Estivill, Maria Novatchkova, Felix Bayerl, Lisa Hoffmann-Haas, Francesco Andreatta, Trung Nguyen, Milica Vulin, Jan Boettcher, Anna Obenauf

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1637; DOI: 10.1136/jitc-2023-SITC2023.1473
1474 Investigating the molecular architecture of triple positive breast cancer samples with spatial omics technologies
Katherine Elston, Jessica Runyon, Vijay Baichwal, Arne Christians, Weston Stauffer, Analise Leddy, Savannah Santoro

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1638; DOI: 10.1136/jitc-2023-SITC2023.1474
1476 A novel therapeutic approach targeting stroma of pancreatic cancer using an innovative anti-microbial approach
Kajal Gupta, Eileena Giurini

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1640; DOI: 10.1136/jitc-2023-SITC2023.1476
1477 Neuronal modulation of myeloid cells in glioblastoma
John C Hancock, Mark Gilbert

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1641; DOI: 10.1136/jitc-2023-SITC2023.1477

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