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72 Virtual stain overlay: a novel approach for evaluating tumor microenvironment (TME) specific expression of PD-L1 in whole slide images of lung cancer
Brian Cone, Thomas Jensen, Zihang Fang, Kevin de Haan, Serge Alexanian, Luis AV Carvalho, Yair Rivenson, Raymond Kozikowski

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A82; DOI: 10.1136/jitc-2023-SITC2023.0072
73 Quantifying the effect of microsatellite instability and mismatch repair deficiency on the tumor microenvironment
Jake Conway, Daniel Borders, Bahar Rahsepar, William Qian, Maria Guramare, Syed Ashar Javed, Michael Nercessian, Michael G Drage, Amaro Taylor-Weiner

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A83; DOI: 10.1136/jitc-2023-SITC2023.0073
74 Abstract withdrawn
Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A84; DOI: 10.1136/jitc-2023-SITC2023.0074
75 The mutational landscape defines the proteome and spatial organization of tumor, stroma, and immune cells in ovarian cancer
Kruttika Dabke, Bassem Ben Cheikh, Nicole Gull, Amisha Dhawan, Katrina Evans, Sarah Parker, Michelle Jones

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A85; DOI: 10.1136/jitc-2023-SITC2023.0075
76 Customizable polymer-based synthetic cells for imaging flow cytometry
Martina de Geus, Daixuan Zhang, Juan Armas

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A86; DOI: 10.1136/jitc-2023-SITC2023.0076
77 Analyzing effects of immunotherapies, such as bispecific antibodies and cellular therapy, targeting EGFR expression with a high content screening platform in patient-derived organoids
Saskia de Man, Chiara Foini, Tomas Veenendaal, Sergei Chavez-Abiega, Michelle Kop, Rick Heeren, Christos Sarantaris, Daniel Okkes, Ashgard Weterings, Sander Basten, Leo Price, Gera Goverse

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A87; DOI: 10.1136/jitc-2023-SITC2023.0077
78 Application of novel AI-assisted technology in ¹⁸F-FDG PET-CT scan analysis – predicting disease response in metastatic melanoma patients undergoing immunotherapy
Mikaela Dell’Oro, Roslyn J Francis, Elin Gray, Nick Reynders, Daniel Huff, Rajkumar Munian-Govindan, Timothy Perk, Martin A Ebert, Michael Millward

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A88; DOI: 10.1136/jitc-2023-SITC2023.0078
79 Multiplexed detection of RNA and protein to interrogate the tumor-immune landscape with a novel automated RNAscope™ assay
Sonali Deshpande, Anushka Dikshit, Ge-Ah Kim, Julia Yu, Laetitia Chatelain, Nancy George, Li-Chong Wang, Maithreyan Srinivasan

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A89; DOI: 10.1136/jitc-2023-SITC2023.0079
9 Advanced orthotopic ovarian cancer patient-derived xenograft models for improved preclinical evaluation of immunotherapies
Katrin Kleinmanns, Martine Lode, Stein-Erik Gullaksen, Luka Tandaric, Nicholas Casey, Sebastién Wälchli, Line Bjørge, Emmet McCormack

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A9; DOI: 10.1136/jitc-2023-SITC2023.0009
80 Association of in situ T-cell receptor diversity and tumor adjacent immune cells to checkpoint inhibitor response in head and neck squamous cell carcinoma (HNSCC)
Li Fan, Angelo Harris, Patrick Franken, Matthew Loya, Gabrielle Suppa, Nora Pencheva, Susan Sun, Anantharaman Muthuswamy, Homer Adams, Mark Fereshteh, Omar Jabado

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A90; DOI: 10.1136/jitc-2023-SITC2023.0080

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