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53 Inducing immune response with FLASH and conventional radiation in diffuse midline glioma (DMG)
Hanna Minns, Oscar Padilla, Hong-Jian Wei, Robyn D Gartrell, Andrea Webster-Carrion, Masih Tazhibi, Nicholas McQuillan, Xu Zhang, Matthew Gallitto, Rebecca Yeh, Zhiguo Zhang, Tom Hei, Luca Szalontay, Jovana Pavisic, Guy Garty, James Garvin, Peter Canoll, Claire Vanpouille-Box, Vilas Menon, Marta Olah, Raul Rabadan, Cheng-Chia Wu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A62; DOI: 10.1136/jitc-2023-SITC2023.0053
54 Exploring urinary biomarkers in NMIBC: assessing sample quality window and the feasibility of immune profiling in urine samples
Alexandra Sevko, Claudia Prevosto, Laurent Derre, Livija Deban

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A63; DOI: 10.1136/jitc-2023-SITC2023.0054
55 Exploring proximal biomarkers of CBL-B inhibition in human peripheral blood mononuclear cells
David Greco, Yilin Qi, Jun Kuai, Samira Jaeger, Yingzhi Bi, Huadong Sun, Wei Liu, Ken Carson, Timothy Reilly, Geraldine Harriman, Fang Wang, Hadi Danaee

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A64; DOI: 10.1136/jitc-2023-SITC2023.0055
56 Vibrational spectroscopy with metasurface optics (VISMO) – a new platform for label-free spatial profiling of the tumor-immune environment
Kai Chang, Baba Ogunlade, Mamatha Serasanambati, Varun Dolia, Fareeha Safir, Jack Hu, Clint Luna, Feng Pan, Sajjad Abdollahramezan, Hamish Delgado, Amanda Kirane-c, Jennifer Dionne

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A65; DOI: 10.1136/jitc-2023-SITC2023.0056
57 Functional binding of PD1 ligands predicts response to anti-PD1 treatment in patients with cancer
Moshe Elkabets, Bar Kaufman, Angel Porgador

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A66; DOI: 10.1136/jitc-2023-SITC2023.0057
58 Epigenetic editing as a promising strategy to enhance efficacy and genomic integrity of CAR T cell therapy
Shutan Jiang, Hongye Wang, Shaoshuai Mao, Leilei Wu, Yaqin Li, Xiaodong Huang, Bob Zhang

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A67-A68; DOI: 10.1136/jitc-2023-SITC2023.0058
59 Preclinical platform for nucleic acid drug evaluation: siRNA and mRNA therapeutics
Dong Wang, Xiangnan Qiang, Zhixiang Zhang, Qingyang Gu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A69; DOI: 10.1136/jitc-2023-SITC2023.0059
7 Local and peripheral response to pembrolizumab ± radiotherapy in rhesus macaques with naturally-occurring dMMR colorectal cancer
Simon Deycmar, George W Schaaf, Brendan J Johnson, J Daniel Bourland, James D Ververs, Christopher T Whitlow, J Mark Cline

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A7; DOI: 10.1136/jitc-2023-SITC2023.0007
60 Development of a gene signature to predict the anti-tumor response of the salt-inducible kinase (SIK) inhibitor OMX-0407
Ilona-Petra Maser, Sonja Lacher, Marisa Stebegg, Vincent Piras, Barbara Kracher, Kai Quirin, Murray Yule, Hannes Loferer, Stefan Bissinger

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A70; DOI: 10.1136/jitc-2023-SITC2023.0060
61 Treatment-specific immune phenotypes in PBMCs revealed by nELISA high-throughput proteomics
Nathaniel Robichaud, Grant Ongo, Woojong Rho, Ivan Teahulos, Milad Dagher

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A71; DOI: 10.1136/jitc-2023-SITC2023.0061

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