Oncolytic and Local Immunotherapy

In situ vaccination with cowpea mosaic virus elicits systemic antitumor immunity and potentiates immune checkpoint blockade
Chenkai Mao, Veronique Beiss, Gregory W Ho, Jennifer Fields, Nicole F Steinmetz, Steven Fiering

Journal for ImmunoTherapy of Cancer Dec 2022, 10 (12) e005834; DOI: 10.1136/jitc-2022-005834
Systemic cellular viroimmunotherapy for canine high-grade gliomas
Ana Cloquell, Isidro Mateo, Stefano Gambera, Martí Pumarola, Ramon Alemany, Javier García-Castro, Ana Judith Perisé-Barrios

Journal for ImmunoTherapy of Cancer Dec 2022, 10 (12) e005669; DOI: 10.1136/jitc-2022-005669
Intratumoral oncolytic virus V937 plus ipilimumab in patients with advanced melanoma: the phase 1b MITCI study
Brendan D Curti, Jon Richards, John R Hyngstrom, Gregory A Daniels, Mark Faries, Lynn Feun, Kim A Margolin, Sigrun Hallmeyer, Mark Grose, Yiwei Zhang, Anlong Li, Robert H I Andtbacka

Journal for ImmunoTherapy of Cancer Dec 2022, 10 (12) e005224; DOI: 10.1136/jitc-2022-005224
Phase I/II study of PexaVec in combination with immune checkpoint inhibition in refractory metastatic colorectal cancer
Cecilia Monge, Changqing Xie, Yuta Myojin, Kelley Coffman, Donna Mabry Hrones, Sophie Wang, Jonathan M Hernandez, Bradford J Wood, Elliot B Levy, Israa Juburi, Stephen M Hewitt, David E Kleiner, Seth M Steinberg, William D Figg, Bernadette Redd, Philip Homan, Maggie Cam, Benjamin Ruf, Austin G Duffy, Tim F Greten

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005640; DOI: 10.1136/jitc-2022-005640
PKR induces TGF-β and limits oncolytic immune therapy
Bangxing Hong, Upasana Sahu, Matthew P Mullarkey, Evan Hong, Guangsheng Pei, Yuanqing Yan, Yoshihiro Otani, Yeshavanth Banasavadi-Siddegowda, Huihui Fan, Zhongming Zhao, Jianhua Yu, Michael A Caligiuri, Balveen Kaur

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e006164; DOI: 10.1136/jitc-2022-006164
Personalized neoantigen viro-immunotherapy platform for triple-negative breast cancer
Renato Brito Baleeiro, Peng Liu, Louisa S Chard Dunmall, Carmela Di Gioia, Ai Nagano, Lauren Cutmore, Jun Wang, Claude Chelala, Lydon Wainaina Nyambura, Peter Walden, Nicholas Lemoine, Yaohe Wang

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007336; DOI: 10.1136/jitc-2023-007336
Functional tumor cell-intrinsic STING, not host STING, drives local and systemic antitumor immunity and therapy efficacy following cryoablation
Mohammad Alshebremi, Suzanne L Tomchuck, Jay T Myers, Daniel T Kingsley, Saada Eid, Muta Abiff, Melissa Bonner, Shahrazad T Saab, Sung Hee Choi, Alex Yee-Chen Huang

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e006608; DOI: 10.1136/jitc-2022-006608
Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments
Maulasri Bhatta, Gautam N Shenoy, Jenni L Loyall, Brian D Gray, Meghana Bapardekar, Alexis Conway, Hans Minderman, Raymond J Kelleher Jr, Beatriz M Carreno, Gerald Linette, Leonard D Shultz, Kunle Odunsi, Sathy V Balu-Iyer, Koon Yan Pak, Richard B Bankert

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003148; DOI: 10.1136/jitc-2021-003148
Leveraging immune memory against measles virus as an antitumor strategy in a preclinical model of aggressive squamous cell carcinoma
Victoria M Leb-Reichl, Melanie Kienzl, Anna Kaufmann, Angelika Stoecklinger, Birgit Tockner, Sophie Kitzmueller, Nadja Zaborsky, Markus Steiner, Gabriele Brachtl, Lisa Trattner, Patrick Kreideweiss, Christian Reinsch, Steffen Panzner, Richard Greil, Dirk Strunk, Johann W Bauer, Iris K Gratz, Christina Guttmann-Gruber, Josefina Piñón Hofbauer

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002170; DOI: 10.1136/jitc-2020-002170
Eliciting an immune-mediated antitumor response through oncolytic herpes simplex virus-based shared antigen expression in tumors resistant to viroimmunotherapy
Mohammed G Ghonime, Uksha Saini, Michael C Kelly, Justin C Roth, Pin-Yi Wang, Chun-Yu Chen, Katherine Miller, Ilse Hernandez-Aguirre, Yeaseul Kim, Xiaokui Mo, Joseph R Stanek, Tim Cripe, Elaine Mardis, Kevin A Cassady

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002939; DOI: 10.1136/jitc-2021-002939

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