Oncolytic and Local Immunotherapy

Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity
Xiaofei Yu, Wenjie Liu, Shixian Chen, Xueqian Cheng, Patrick A Paez, Tuanwei Sun, Fang Yuan, Chunyan Wei, Joseph W Landry, Andrew S Poklepovic, Harry D Bear, John R Subjeck, Elizabeth Repasky, Chunqing Guo, Xiang-Yang Wang

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001595; DOI: 10.1136/jitc-2020-001595
A systemically deliverable Vaccinia virus with increased capacity for intertumoral and intratumoral spread effectively treats pancreatic cancer
Giulia Marelli, Louisa S Chard Dunmall, Ming Yuan, Carmela Di Gioia, Jinxin Miao, Zhenguo Cheng, Zhongxian Zhang, Peng Liu, Jahangir Ahmed, Rathi Gangeswaran, Nicholas Lemoine, Yaohe Wang

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001624; DOI: 10.1136/jitc-2020-001624
IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy
Tianyue Chen, Xiangqing Ding, Qibin Liao, Nan Gao, Ye Chen, Chen Zhao, Xiaoyan Zhang, Jianqing Xu

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001647; DOI: 10.1136/jitc-2020-001647
Local and distant response to intratumoral immunotherapy assessed by immunoPET in mice
Louis Meyblum, Céline Chevaleyre, Sandrine Susini, Benoit Jego, Frederic Deschamps, Dimitri Kereselidze, Baptiste Bonnet, Aurelien Marabelle, Thierry de Baere, Vincent Lebon, Lambros Tselikas, Charles Truillet

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007433; DOI: 10.1136/jitc-2023-007433
Cytoplasmic-delivery of polyinosine-polycytidylic acid inhibits pancreatic cancer progression increasing survival by activating Stat1-CCL2-mediated immunity
Praveen Bhoopathi, Amit Kumar, Anjan K Pradhan, Santanu Maji, Padmanabhan Mannangatti, Jolene J Windle, Mark A Subler, Dongyu Zhang, Vignesh Vudatha, Jose G Trevino, Esha Madan, Azeddine Atfi, Devanand Sarkar, Rajan Gogna, Swadesh K Das, Luni Emdad, Paul B Fisher

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007624; DOI: 10.1136/jitc-2023-007624
Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, Jose Gonzalez-Gomariz, Celia Gomar, Joan Salvador Russo-Cabrera, Irene Olivera, Assunta Cirella, Myriam Fernandez-Sendin, Maite Alvarez, Alvaro Teijeira, Cigdem Atay, José Medina-Echeverz, Maria Hinterberger, Hubertus Hochrein, Ignacio Melero, Pedro Berraondo, Fernando Aranda

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e006702; DOI: 10.1136/jitc-2023-006702
Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity
Clément Anfray, Francesco Mainini, Elisabeth Digifico, Akihiro Maeda, Marina Sironi, Marco Erreni, Achille Anselmo, Aldo Ummarino, Sara Gandoy, Francisco Expósito, Miriam Redrado, Diego Serrano, Alfonso Calvo, Marvin Martens, Susana Bravo, Alberto Mantovani, Paola Allavena, Fernando Torres Andón

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002408; DOI: 10.1136/jitc-2021-002408
Simple and effective bacterial-based intratumoral cancer immunotherapy
Christina S E Carroll, Erin R Andrew, Laeeq Malik, Kathryn F Elliott, Moira Brennan, James Meyer, Alexander Hintze, Andrew A Almonte, Cassandra Lappin, Philip MacPherson, Klaus-Martin Schulte, Jane E Dahlstrom, Rohit Tamhane, Teresa Neeman, Elizabeth W Herbert, Maurice Orange, Desmond Yip, Rachel Allavena, Aude M Fahrer

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002688; DOI: 10.1136/jitc-2021-002688
Elucidating mechanisms of antitumor immunity mediated by live oncolytic vaccinia and heat-inactivated vaccinia
Weiyi Wang, Shuaitong Liu, Peihong Dai, Ning Yang, Yi Wang, Rachel A Giese, Taha Merghoub, Jedd Wolchok, Liang Deng

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002569; DOI: 10.1136/jitc-2021-002569
Adaptation of transgene mRNA translation boosts the anticancer efficacy of oncolytic HSV1
Huy-Dung Hoang, Aida Said, Nasana Vaidya, Victoria H Gilchrist, Kyle Malone, Usha Kabilan, Serena Topshee, Xiao Xiang, An-Dao Yang, David Olagnier, Karen Mossman, Shawn T Beug, Seyed Mehdi Jafarnejad, Samuel T Workenhe, Tyson E Graber, Tommy Alain

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e006408; DOI: 10.1136/jitc-2022-006408

Main menu

Oncolytic and Local Immunotherapy

Pages

Log in using your username and password

Main menu

Log in using your username and password

You are here

Oncolytic and Local Immunotherapy

Pages