Oncolytic and Local Immunotherapy

Direct and indirect immune effects of CMP-001, a virus-like particle containing a TLR9 agonist
Shakoora A Sabree, Andrew P Voigt, Sue E Blackwell, Ajaykumar Vishwakarma, Michael S Chimenti, Aliasger K Salem, George J Weiner

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002484; DOI: 10.1136/jitc-2021-002484
Natural killer T cell immunotherapy combined with oncolytic vesicular stomatitis virus or reovirus treatments differentially increases survival in mouse models of ovarian and breast cancer metastasis
Simon Gebremeskel, Adam Nelson, Brynn Walker, Tora Oliphant, Lynnea Lobert, Douglas Mahoney, Brent Johnston

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002096; DOI: 10.1136/jitc-2020-002096
Combination immunotherapy using G-CSF and oncolytic virotherapy reduces tumor growth in osteosarcoma
Alvaro Morales-Molina, Stefano Gambera, Angela Leo, Javier García-Castro

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001703; DOI: 10.1136/jitc-2020-001703
T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A⁺CD141⁺ cDC1 and CD14⁺ antigen-presenting cell recruitment
Bas D Koster, Marta López González, Mari FCM van den Hout, Annelies W Turksma, Berbel JR Sluijter, Barbara G Molenkamp, Paul AM van Leeuwen, Saskia Vosslamber, Rik J Scheper, Alfons JM van den Eertwegh, M Petrousjka van den Tol, Ekaterina J Jordanova, Tanja D de Gruijl

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001962; DOI: 10.1136/jitc-2020-001962
Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche
Louise M E Müller, Gemma Migneco, Gina B Scott, Jenny Down, Sancha King, Basem Askar, Victoria Jennings, Babatunde Oyajobi, Karen Scott, Emma West, Christy Ralph, Adel Samson, Elizabeth J Ilett, Munitta Muthana, Matt Coffey, Alan Melcher, Christopher Parrish, Gordon Cook, Michelle Lawson, Fiona Errington-Mais

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001803; DOI: 10.1136/jitc-2020-001803
Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB–IVM1c melanoma
Josep Malvehy, Igor Samoylenko, Dirk Schadendorf, Ralf Gutzmer, Jean-Jacques Grob, Joseph J Sacco, Kevin S Gorski, Abraham Anderson, Cheryl A Pickett, Kate Liu, Helen Gogas

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001621; DOI: 10.1136/jitc-2020-001621
In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models
Takaaki Oba, Kenichi Makino, Ryutaro Kajihara, Toshihiro Yokoi, Ryoko Araki, Masumi Abe, Hans Minderman, Alfred E Chang, Kunle Odunsi, Fumito Ito

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002432; DOI: 10.1136/jitc-2021-002432
Initial dose of oncolytic myxoma virus programs durable antitumor immunity independent of in vivo viral replication
Erica B Flores, Bulent A Aksoy, Eric Bartee

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000804; DOI: 10.1136/jitc-2020-000804
Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma
Lihong Wang-Bishop, Mohamed Wehbe, Daniel Shae, Jamaal James, Benjamin C. Hacker, Kyle Garland, Plamen P. Chistov, Marjan Rafat, Justin M. Balko, John T. Wilson

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000282; DOI: 10.1136/jitc-2019-000282
Oncolytic vesicular stomatitis virus–based cellular vaccine improves triple-negative breast cancer outcome by enhancing natural killer and CD8⁺ T-cell functionality
Seyedeh-Raheleh Niavarani, Christine Lawson, Marie Boudaud, Camille Simard, Lee-Hwa Tai

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000465; DOI: 10.1136/jitc-2019-000465

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