{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022GaRosxS2IoHNH8QwkztScwTYx5GyGpdB0xrzAjjBmd3463gReENwScvDRoUs06t6V87Chg0KMjQx8cynYHTXqiPDwkIuU5GFHbGXL9ELvUHO8W0KGt463C5QMJU6KMZVL2rbas+bREEWYziGC8JPibgnw9CnY1tgmyYOA9qKEP5L9UbyX\\\\\\\\\\\\\\\/UlZhIL4xIWn12GCTW+9he3n21SubnVELu1qJn7Y4dbsMlYpDzLexV6GyHFzdYfjfs32Ergf\\\\\\\\\\\\\\\/Of8sksOLMwoFk\\\\\\\\\\\\\\\/VtDGiOECKfx1aq1N5\\\\\\\\\\\\\\\/Nre+33V2vag4f1NtEQXTPSDsGH+fjqomK7YthLIa+ngoAZBEwr6wl8dT5LaTfewUzeOA0wzsu3+3YyliUZvuX5pJgtQxjb1CLhWF\\\\\\\\\\\\\\\/wJSTvLXMlBfUqURmriQg3WKzobDCZncxkrOsJFYKHh9Y8ee2Y\\\\\\\\\\\\\\\/X89wspIeamyn80FRv7ogjOQZ7\\\\\\\\\\\\\\\/JVIMtSvB4pdKSXxUx0oi0a1E30pycrHDF1yNQGIseY1YlOOAOsuKg1+UHJkuMf\\\\\\\\\\\\\\\/kwmNvlxKq5iWST1KweI2P\\\\\\\\\\\\\\\/4EXxOHqQ53OamCiT\\\\\\\\\\\\\\\/tgrGcrcCX\\\\\\\\\\\\\\\/TxOJUpsdUJWCE0a+wsJRqFNHFrd0fl2X\\\\\\\\\\\\\\\/tWw3WKI2ioTv8IdTd2ANa8hrC4fKMHRZmtZ4RqSr5aOHZIS9MrCL+kgaht6305WsSe6\\\\\\\\\\\\\\\/5hw17QonPuCMJyjvLVLk13Ur3pbWUla3NvxxrfAy4HkVN1DnZUgNnWvKFbQMp5VbpeQb5psmGiF9Hxq8M3riCTwCvpwQSaTl1FnKbKlh4f3lRUnBz08sFLlvYWZ8wAsTkZif6kjZwZze6zQ6vjy3SJ2sS5SNi4sTuWh07nXJ0MdEoti9EdZkOKgAGDgpluSCLzNii7HuNTpq+pelkDKXjBtQO1rdCRgpsIXdJjq1Zwf\\\\\\\\\\\\\\\/M3MW7NcFfAHjfCU9g5Vv+dlRjBD4oF87G8v62\\\\\\\\\\\\\\\/HNV1pFjuC9ptyqvEu6keC9MoPE+xJigb92AYa1D7hUD9SmgCYUETsy1QCgb2X2DP5b+a7ZIE+liVBeMlQj0X3OwS2fdZGYP+0ifyTqhdZAbuXwAF5AO5wiQJS14aGX8zZZ0FgDZxGlvYa7DboHq\\\\\\\\\\\\\\\/qoYATtsYnOzTJu79ByUe1GAXN4nn76l\\\\\\\\\\\\\\\/VmEfi7VXRDB9jVCmLxlr+gJ5VrofTqjZnJPTma6fhijIA0QNunzg2Y8okiBpWgp2sUmv639kTE8572rxbBpMr81isfz6rNRFExS9jk9ZNeorpRDvK5Hks74U26pKtNCL5tZ3zgRi6UXBn9LUofiF8vBvdphQ9uDSzf41VVPtscDX0sqePElQc7tVTabIm7+NZJQlHz2j83DMAtyJbBZvyFDOOkKEfVmL3rE9AOs9xpUfE+Dbmq6cSvg0WJ2D8uBzMsTmjj+YqdQo0d6+fsRJ2WCkAh08fZCsi4PZtee6UqKOE8RScSmP4mq+u\\\\\\\\\\\\\\\/9fYU4NGFq\\\\\\\\\\\\\\\/6\\\\\\\\\\\\\\\/oTDBaVrTJjwIJitA2bJryUc00iPoFgSIecLqh7GS2rM9bON60a\\\\\\\\\\\\\\\/VmHN38UbYtSotbdZ9poaMDzhdWW9x\\\\\\\\\\\\\\\/2mI359I9xw2sc0X0jpPNSZ0MIfaunfFyxsdUa\\\\\\\\\\\\\\\/xS\\\\\\\\\\\\\\\/bp2foJdrbZuDooqJNE36BVAb5OOqbZiwf7ZF2qtAwzbNwtBXOK8VlbCxl0nL1KOnRq9Wmud6YB93Tk1eun9YtLbzfyY1iORQSFDtwO0tUG21orWak13F45y24eTZwlo2nBfEcG2CiZfbi6Y4fwytS+YQ5zabPAW3+I7XruVqw\\\\\\\\\\\\\\\/PWnIsEiqzin5efHqvfIMpGeVIY2isM88m2XRhmj7nhmLNolIFj+WtAyg8YnDO+arkK6AJnT4fZ8bp0o5gSMZ5EuaK0DAjxBO9JwSv3bum1w0k57u+rc7jt5290CpPeegqzdTMp1qHHmYOOgd0LBrA4eMjaL2EIV\\\\\\\\\\\\\\\/YK0D3msm0jEWzNcn6TAzByepnFDAC\\\\\\\\\\\\\\\/1XX+b9YA5QYKO4hjA\\\\\\\\\\\\\\\/t6eCxGd5ymeO3otnWryUyTLvPTIzIQ9S6vO0\\\\\\\\\\\\\\\/WcE4XtGopoBjADLTfe3a86QkKV\\\\\\\\\\\\\\\/apXG1u9eXpKr5iNNNK2fnqjT\\\\\\\\\\\\\\\/EvYhJ0IGO4Lih8J3U7gEeJKxtqr7W566kBIABBOCAV8HouwO0X3dGneDqXLJvNGu4DS5pHH4iwKLkIx7ypUulklyCmyw3Id92oUfDCup3FpUtpAtDDCdnnehL9tEaayWfxX3B3FlE20DNkXih+rCVfXemCHY5MZMwin\\\\\\\\\\\\\\\/JZO9yHVvK3fSpxheZzKRH3T43xG\\\\\\\\\\\\\\\/N4mtL5sn38cv5BUyCOTLJQu9yUBwWKlFKhbsA9vlNxGSIKUo+WJ1qjC9Abw098d6o\\\\\\\\\\\\\\\/BvI10qsJYSFKKvh1mU54ObPNScH8B0H5PTKV1DYjAlzo1lny8iK7ocXXFF\\\\\\\\\\\\\\\/1VKB2rJZsoPzmE3k3UciJ3LS+oADjUw8SQqzfVriX4oMWG4ObeXdG4zXZAXh4xAMmQNhV\\\\\\\\\\\\\\\/N9EaWkZW7gSbX6V5JQTYjRX7f\\\\\\\\\\\\\\\/cSMYXd9gaePi5+nnuffiLuJA070Dgxtq+BGsK97gKc8CtfnWMvdo7yx6XAWax6WH9J1X7TuulkWnXLqp2OMn6qtE9mWwZReOvAKVYrNHb\\\\\\\\\\\\\\\/8CZl3uDQfIKHYCQh0FTuD9DiQL7FTjUzdyIRVoeV4Y8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u002212eskag1tj16xTyyjcZs1A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b6a6f3aa4695380c254b665765e87d3c5037c7007c3444ddffa2df45ada8a4a2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/12\\\/8\\\/e009210.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/12\\\/8\\\/e009210.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2024-009210\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2024-009210\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2024-009210\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}