{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022HVeTd4PV1neZMoNOqGTv\\\\\\\\\\\\\\\/pnIeICfd7m6NuSkm9gf31+L75CyRK3nPUPkyJXf\\\\\\\\\\\\\\\/MP0e5Tj3EtQVtbJ\\\\\\\\\\\\\\\/fMFVx0n13JXf7AdmEWITQngon6u9s8KIsoFeN4vJH3pX4qWD6Zn4IGYebgukWsvgqs8apbyo7\\\\\\\\\\\\\\\/w1rqTzbs1X4\\\\\\\\\\\\\\\/wPbgABM3\\\\\\\\\\\\\\\/B82r5xe5qrKZS2bJADiAARNjhTFveIqFYLezYyUD0dOT2+TQlMBfCOTWaCMk0nRhuoCSa9Wr\\\\\\\\\\\\\\\/u41PDA3hAAHf7m9SYbiTYu3IDp+0a3AxbXeV\\\\\\\\\\\\\\\/63fDHrtJHsp+CeKlhwopwHvmLirrHZqcbQoXv8U5yAxQ9bWUhKyzJScCtxy1XfDYW8Ec8ZE3xePwwWsDpSaT6zBd4vpH36tZPFfjVA0sv52GZrSG9sjrR6t1eUYsOmR6\\\\\\\\\\\\\\\/Fh+fqP\\\\\\\\\\\\\\\/4q9DUYjKCce4NYL8utOW0sWa1UWODuQnO6dilTGPb1z2Gj5sOdqOCtOZPWolJ0oAPvPy4yscDB5y9dcXYMGL8dH0N7mOPnqH2ezezbAKQ3zfHucnCge+cXpThD7iDISu2Y3VTwRtOv6c5WHWdrcDpTCJhQp3wJ01VpNjgQTXClrJ91vusYuK+b5SnORc55UgS10+DXkXN95+fWKHN7r0PMhcM\\\\\\\\\\\\\\\/knH0jJxgdGeKp6j19w+kSrNpoB4ZQ5ZnChNLX6V+4nGwD8KN+mdhCWEkZJ2MAYbKSs1RWVCGTfSi8NG4zXEVEnBOUez41fjw6xzpoQgopI\\\\\\\\\\\\\\\/E2cGABLyU\\\\\\\\\\\\\\\/RPeyHvqfecR4mMnU97\\\\\\\\\\\\\\\/rAKacwKpmrUb1F2BBCdWMFqCE9\\\\\\\\\\\\\\\/t0MlaVyCPpI5bsIxQYklHc9eZGraOV49GAYCQNM8DuhcQgg623MgLWH5I6sujtmmBp4ovSjSPvAsQZlthPsXcaF8FNSjtQ4ev1KePgewdDeTqwBIxX8+Y+EMwxQVyUf1dikJDHa4AH5uKTkzYIE5cpbCOa91n2+klgJ47MZJ4icMMpZjJt67RfH39O5az\\\\\\\\\\\\\\\/EUjMKqtfMFIKtmv9j4UX\\\\\\\\\\\\\\\/8fu3dvvG+x9js1m1j9tdtakh9pYJPKLmieb1NXZofi3Ehs0ALg3ffSVWvekvuVpo9TkLrD\\\\\\\\\\\\\\\/1tq\\\\\\\\\\\\\\\/KgqjmpkxwLKc5cKbjHXYrdvbgJzezLVXNGPw8mLJGSf9SF\\\\\\\\\\\\\\\/lfeA5Q7NXHcqJ6llFCDZnTt5LiN7pm\\\\\\\\\\\\\\\/hUcvFxsm4t2eys6rh1Ga1\\\\\\\\\\\\\\\/GklL3dC2UEOivC7Ce5L9A7YVkTfml3\\\\\\\\\\\\\\\/bDOC8XdGxck0yNcE+aXYxkY9XoNxRfZUbSTMpvXtATi\\\\\\\\\\\\\\\/LWrI9BO4kCUPYz+rnGEJ1cH43JM7v7KidCDQWIyTH\\\\\\\\\\\\\\\/cTGnMzlc\\\\\\\\\\\\\\\/nMgji8RP\\\\\\\\\\\\\\\/JMVGQTnMo4MouaoDPRnRrAH8zMf7LypzhYJhI6lOdMp\\\\\\\\\\\\\\\/WSDWRMzQ27oB38lW\\\\\\\\\\\\\\\/837N1uwGRglMakK5SnWBk+qD6XPtozjAWZZhOle6mR7Bq5JZo+u+0tH7wEU5C9OjhmaP46LuemJXA23be\\\\\\\\\\\\\\\/75cXAUH6g0Ru\\\\\\\\\\\\\\\/CIeEJNyp1t0+w2N1thwhyz5aH\\\\\\\\\\\\\\\/uv0LIevHNoS1qk9WwxQxhQllX08JDJgRKzP09WSPZxSEdEqoCmUcXlUvPlzUGZmXShTRR3j0UFc0CKWXoiEXeV\\\\\\\\\\\\\\\/iTAhUqCAZZPQbARD9GQisjapoUbQXFLkI6Afl3hZNl4MDe3K73LcNHWSLoMw32jf1GhLE84GbxGlfYV+pUK3o8XFZHE2Ij+ab4+rhwokqCtFDTaO0fX4cedmEgSYsYrBNUATdAaan83RNujvZ2BaXKYdL2+hrkXxxnWL3BQ1vG6krveidfHhDguIsWnH\\\\\\\\\\\\\\\/Bbm2mK0PgQ7CgvLqRjv5k3btmJsnLOYY0DZUzKR\\\\\\\\\\\\\\\/t3qTZpREvxyLWjNr4lSMdXygSIe9jQoA1ZHl2cO08gNY8U77aVTyNY7EFh6Z0xB+fdmN9\\\\\\\\\\\\\\\/BOiiXp0Jk0ejz1hiAr0PTfcfRfL3bPX1UuMh2cBW6R\\\\\\\\\\\\\\\/mbKQfBHctM02J+m7NkOfj68MiENeCijr+gl5vBoLdtIzEZ5T\\\\\\\\\\\\\\\/Wj\\\\\\\\\\\\\\\/ZqD6HEE5UvAhxIe3m1QxDRrpJYe5vBKRjudN77M50\\\\\\\\\\\\\\\/2Fm93BJUgP8T\\\\\\\\\\\\\\\/UHx7eob6R+ZvYwvw3NthAEAFvG8WgcYM9z6u3bsP1T3zjsNQxF7prEESoQrtUmTIFMbxpb\\\\\\\\\\\\\\\/6BJ9u\\\\\\\\\\\\\\\/ox7Wyo\\\\\\\\\\\\\\\/4qeU8PYjuBfw\\\\\\\\\\\\\\\/Q41yKm29wARJ\\\\\\\\\\\\\\\/vGysTS\\\\\\\\\\\\\\\/wkxK8EExgJd0Tmen8kz9k029dECUtpm84O\\\\\\\\\\\\\\\/hXmo08RRBUGfRFyt4nmt9IBL4gB6xe1MMzLbRfxynH5I2dm2dUVvTiB\\\\\\\\\\\\\\\/Ba4uvZDPep2TuAf+1y3Yn3\\\\\\\\\\\\\\\/KxY3myyqN0FxBRCE4X3p0kZxN0ZcI21lnJqnIzAJm76C\\\\\\\\\\\\\\\/OtiFT8DPES8coOO8zvGq\\\\\\\\\\\\\\\/FdY3KNXvQb0WJVvqquXoNteN+kqRxfG28d1sYaXYHqueL8AvOY7ot2vUTCZWSlzKnpbrTFFrsYpK85zQnTs\\\\\\\\\\\\\\\/J9cp1fxrgiAEEeZrlcVEdFrGY2bmsOBmkqoFv7Q16MrdBsxeOZbTciwV4nSB4lqi2ru3T6EBWfpQMLtJKSNeUvm6fcyIbC9mmo0jY+sKdXFPRsORfjFKiHIagR2VNrrSK9dxfCyBvLk8H1VPvPi7NKE\\\\\\\\\\\\\\\/0nCpARvWpjbyt0\\\\\\\\\\\\\\\/Gn8b219qDRwgupHhE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022VkRMD+3AaCPILFHwRYlQ6A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223c91d16c2afb1de119a2ab5e050acf664487598c86e415a5d03514f907c1c262\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/12\\\/Suppl_1\\\/A23.1.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/12\\\/Suppl_1\\\/A23.1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2024-ITOC10.42\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2024-ITOC10.42\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2024-ITOC10.42\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}