{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022m1PMHpHpZeqUmlrAnJ7BJKjgjE4Y7S+YAx5kDxgiqWz6mLnzC9G++M1n8qJHlS4XP+041Psclo8vyMVMuCcEDqlU7R1dgkHrlcC6SCAZVL5XzX2dM850JoUkQda02RLRoa9qNP0pU7FY5GHudrn2yBL9o7sYrQPQInIPthjlEmlIhqkB8s4wiJkguuny6XbbgA9GD1H+ZCsEr8Ksh2O4r0pRREgzm9IERsJExGd9973jJ84jvdi7+NWsdXgNWzKxr2h9U\\\\\\\\\\\\\\\/VZkagwr7\\\\\\\\\\\\\\\/tiSwVE9zNHKh\\\\\\\\\\\\\\\/JDjfedMOpAFJ6os\\\\\\\\\\\\\\\/hFwV55\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/2ryeypUVNC+8\\\\\\\\\\\\\\\/HKOYxNPsxQr+HIk2+qzmBkzc0WX9eh3PIAmC4t0hsD0xWRQvgQBthmfiQYg6uQFivupnyaLtmRMgBC+gK\\\\\\\\\\\\\\\/vNStnAAQRo6acoMU1hEYRVUJjDY0BGXMhSqpAB8zg4kwl\\\\\\\\\\\\\\\/Yq\\\\\\\\\\\\\\\/3O0hyfZtblOwS+rfRECFLYIVqXRDHGnLuYisM1oQcBz8PPbUswhdK4ojCLJXsYs4hHwlzrUr\\\\\\\\\\\\\\\/0N6jZPWTyXkiIFQiIyku2a9uVDYYt5cWXAfV\\\\\\\\\\\\\\\/zZUHj+VzNG\\\\\\\\\\\\\\\/q\\\\\\\\\\\\\\\/5utKKw+kHJof9OYyRaJmMgH160BbonvpPj0GEQBExs4fGaLx7RWKNJZIoY2FA\\\\\\\\\\\\\\\/EEFdfDnvuGcIIz3erwAgrj04pbx4QUXfV5mCYDsTzUUEldBe7H3HrdS4sbeOoKG97X3X08NWNDhh0MdYCHptH7la7VG+7LXlV1loRcrWrlJJHil0R9d9f2J4wtokTwdYd\\\\\\\\\\\\\\\/xjeBqxdOlwgfVE1\\\\\\\\\\\\\\\/hfBrEQ5HfFMbesdRbIArLFqUMv+tRD0U+TsAkigtgZyFiqM9fjXwXqV7fCUvxmSwXru5gvSNfZXM9r4QjDq2H2h1ljco+GZjJP4+C+PbZ9Ef9Y6xhNUCJexb\\\\\\\\\\\\\\\/hhVGeVvtG4ooQufYKzv7KMaSU5q2gxs0ztk\\\\\\\\\\\\\\\/AlDPFmA3kjj94TL1\\\\\\\\\\\\\\\/y2dJnxLiWOpBIZFqkEj9o5oJZGYIkIZUxFoy29McCJ0kY0WYy8FM80B81BA5cnPRkd4j\\\\\\\\\\\\\\\/qEb0MJ64m73a6mD1VL4f7wkqxLN+sXgnF0Bn2IFOq19G8WcunWZ\\\\\\\\\\\\\\\/zE+\\\\\\\\\\\\\\\/kuy7muYkR+E\\\\\\\\\\\\\\\/W4zkFY4GUVUzq7t\\\\\\\\\\\\\\\/HJjP4CMcwFoKU8O01loh1S3SVJaMur+84zPrB8dkQYuO7IeFPZpwQ2P\\\\\\\\\\\\\\\/Z13mXGff7q8FzIlWcxLDHuR2X9IFu1K5yLjWpWBJGOKZRlrwGm1itoFduejFAL6lG3mO2FgzFcp1IFpWv1UL4fhmXI3VEaZhP0Tc5hXLuFBRLWQ\\\\\\\\\\\\\\\/EnJg4FHB8lQDLdMf2dws20p4CJV5OMANKuBmc3ovOxNnwUjv6gAbF\\\\\\\\\\\\\\\/1a+WMTAvbgrybsWUrk\\\\\\\\\\\\\\\/mjSxlhW2iF0SccRJPl9fgMLv6gKob3KfHaZbAWJwyZu6oQU8lYUnmK1PmN+KEvV\\\\\\\\\\\\\\\/uiY9L9NvT+k\\\\\\\\\\\\\\\/NyPsmSQ5pNxTdMjQfRGHGfUkKdn5IsRviyowep1MNRN9kYGTz1YMHUfMrdDrjQi6PZrY9MHBpcmP8fJXoF6qsoXuJAfGFOpQLJZ6PYiLdwJpyyk9L0Fm9kC1j2B+wnJo6LyPS3XZsBgpR+6iPtJDbvnqacj8hbVgR02fOna7inksVLNL0lpd1fb8jw1uST3XrtcTuqVJPjOdKpFzmD7bcLPSxvQKrnJLkNhofOsAFSVWkbwpC09RVKU0PApgl8AMoJQIUkCMdFhlOS7cWJQPmsPcxOzagX4gaOrzFhN6bIT3m\\\\\\\\\\\\\\\/Yqprkgrm1jsWp9p2EfAXCqbebAWBSjn4CFiE9rZt3ggT9MNUwntn\\\\\\\\\\\\\\\/sZfIDSiVb1Onm6edNZyLm1Md45V2IfKRvg4h\\\\\\\\\\\\\\\/Z5oY14h6L5uPEXlA2Z8jKp2FvNir2mi8pLQ0NbhV2rHVQjUiKWm6McmJYmEaGBz95qKXvs\\\\\\\\\\\\\\\/BlxrgGv7FQjDDUAUArLIK+nGOdFsUjWxbkJmlb1JogXFObmXntPIkjJicfxCENFCAoPrsSodfX6yEuJZklDFJvcfVn8rt4uUNN\\\\\\\\\\\\\\\/fbAYW1sl3PpmbTio0f+fWtc1oVPxAEA9JysC1FYTpecmgEaJN8bD8w3E1uny1ACrcPDvKvHLSUuh+tx16HRswTq2zfO9kGz+KlT165SL2hAIQYM+WFXrmcWYbneQ2wtlGkuxCLv3NG2VXjyIFYEpyae+61sgWzEIL8BYySbIkxosFP+rZeKCt6lPbPSjF+YmPxgz0KCMONh6Q2xsJXUFmaHYKMJZolUx0f8AvLOcYOfmj3cqGdyAqjS9BvMpyLbkIckWlRvVClX5K6FQmjoH30mQYo3D80MnT8PnBGAiXw0BjV4bnQcIlZ9hcsJvf9mIcy6GrdSh5FbClVt2qZdWilrWV8IXw2uuoUjsQaU5RauGNs89fkISTixsbEtEu+aiYdGwPxWrwh\\\\\\\\\\\\\\\/8wgJ3V71U6QLXa6qpDTN6t7xsgZXz9vpKqAbRMWMyMmtOVj6HD33q\\\\\\\\\\\\\\\/PMpdIPBk7vV6c7tnC+TQC0fCAhYjvseFWrkebTJebhkRW88Fdgf1q2s8u0aJyjVOVLDALMkKh83KcINqleOVRfn5QDVujWpAYpO88j9\\\\\\\\\\\\\\\/mGBCJb6rRyH97a1jf4taQYj3pPHNBp+JxHQKoLbEKXim\\\\\\\\\\\\\\\/fhTjwdAtGPZo3ll0=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022bTeM9foj2Yz3HFA1J4hCQw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002238671c1f9c1e5998a5abc34182d4a5afc8b683cfc88ea9da8708ac54fb2965b9\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/12\\\/1\\\/e008026.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/12\\\/1\\\/e008026.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-008026\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-008026\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-008026\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}