{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_KRnV2j6OaoIIxt76AbJVZT143yroXCg9nJWC5fgbkZM.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022id6XOpCbi2hLP6Zw\\\\\\\\\\\\\\\/5mteYCFDUGhlpbR79r81kr8abuLmAdRTSIg4WaTPft8Y8ijOlwbR+h+JxWL0R81LU0LrDXOamWkyQbVU1G3PV8oN\\\\\\\\\\\\\\\/lfF6higlySQCMGC71d6yaWl9ONNR7+HJzm21g\\\\\\\\\\\\\\\/aYiMSjrtHd3t6sndILEdxZOX+tfUxR8KtdmllVV98WUz\\\\\\\\\\\\\\\/JaXokRhW8lJ1uOlBen1EPPN7dlcmprinu3N\\\\\\\\\\\\\\\/FRw1pU8bLzD\\\\\\\\\\\\\\\/WZzT5G1qWvfTq4spX64lOMEefUV7mNOSQf1O0WdQv2HGljRZSgSvHNkM\\\\\\\\\\\\\\\/96m3Mx+6eWRl3q8iuEqgIuQ8nSGfufz+hEIEkMpnS5m5sw+NDD7sPJzD1X7x7YXjn6WgK\\\\\\\\\\\\\\\/QxGkTqF27DnWHHlwmhjZMdiik5k2p3mJCqgig1VFmmRzxlKDrtOsGMOnCFM9HrUKWpl3o5znjwBWN93yMUiLhkZwOSdKxwHKStF2nzTlscZx3vUzFtfqIb1if\\\\\\\\\\\\\\\/5Vl2B7O4YJS9ib3g9kM0SY\\\\\\\\\\\\\\\/S9goMcDo5Tygu5oFFATXff4Ei8iYXPKfUYMw1XE9aU1zKSDtPiO\\\\\\\\\\\\\\\/0SCdRSYrQBbzVf7VckiQ\\\\\\\\\\\\\\\/uOI\\\\\\\\\\\\\\\/TEuM1vcw+1ju0KtxYULwTU3Zm2chjhUf7M3XEc3\\\\\\\\\\\\\\\/m4fWNsUYVeZPaG7nzRAyWV1bE7ifN+YaI0xhmI3mdeGA1f9C1JD3\\\\\\\\\\\\\\\/5qwTqJp6rREYX1U8hBkSlZzLOUXPc4QtdcOzaRJQDbZh4tJ0X+bMDETb5GY\\\\\\\\\\\\\\\/nyEOqUgY3D\\\\\\\\\\\\\\\/BCx67nl9alNtdRyynM6v4qd0CPTUpJLowLcODd1TKIeRg389qu7QH9vSdX17xdg\\\\\\\\\\\\\\\/dxec84H22Oq3N7ofxnIy1j1W0LxgD32VWA9y4tyGFms9t3szO7aAc8JUxVoxIAHUTOJGgeWC8jjx80rP3jb3rGuSkbRx1yw0WReNRcMVUYTyEYCOng2bS+jjEaCfhoQDC\\\\\\\\\\\\\\\/FuBx604quVsJ0S2S06WwJe2onzdDAx0qOmb9FBTvBeDDZp2L7oxhuXsfK2lTqYl0mLb6lavtTGIJH2LNRiPX1bwWbIEqL3wFLF0QaSlqilWHIymRDlOfCyptV9sgP39OXsCU79k6E6UbVy3cJK9KlcuO7d2vJjKoQIB\\\\\\\\\\\\\\\/oA76ufetPlV\\\\\\\\\\\\\\\/8Sak2hfvji8mO7vLw1oNCmuuYqv29KID0PmC6ASIiBWmXlc6kCADjIK4z10CzLVtue0SE\\\\\\\\\\\\\\\/H0IRo4mDd+AeWZRGXQMQt3w3B8Ni0xfXGQ8PsL6kdbgAsevteQUMqk6O1s71EzWDB4aI2eGvLfYggKpC5RcLv4pyYLSEbnNMJCatCzU1iLobdcotlheE9xqq2Ggv8Pa5K4KACuaEiGWQWSlkVae4pIG9yV1KFfxM6nBsAadh9q5CfWaMeavh81HWB1TsldLbMx1y6t3w8dSubKnFtmPdmutcuhOiZcV\\\\\\\\\\\\\\\/ZGa5Q2U3nJEhG4rgkndRGehD+LUnONrPmMx2eDUDRhvWoEEpV\\\\\\\\\\\\\\\/VXtj89yAwtw5+7itVYY\\\\\\\\\\\\\\\/Zh\\\\\\\\\\\\\\\/P+vetLaLWTrL12loUikKI54Fj4rv\\\\\\\\\\\\\\\/mcA3ZS9S0yryJWTmsyJGTxAp9TMxkkLu0EshCrzSWIDbJlpw9Wgiu0fO9kEk42jzBkdFTO+8To3tH45YOwlHvuWw2YhgpAMAbLZgaX0YGY5uNBmEhqJJtwaGFF6xDzJJBVfDUMhk8y\\\\\\\\\\\\\\\/2qt3og8oVmTSZfFSAY7VFDOnh19z5DO75V4UdwsR1xa6WbGESPLlRkTobv48lOqAJfaJnnAd5On6yFVN0Fy24RsYBQj4id7bQJjCOZPmucRyCiOB\\\\\\\\\\\\\\\/jM4b5tJh0X58hAMF8fagU5+HPVqKrV3EedkqmJVSfV7zqLy68MykUCNoD1wQnq65YRK1wAwbdMcQbKjdjpMmAsIMsh5XOL7nL02flvqwMQc5SrIihIiPnnjI2n+1FG+4QcjG+gZDqILR1o5vBeEek0+OinhCKa28W7vQfkLHpsACCx2narD2s4FdjZv8tKbqyOiqvFqjapCEOCVC6x4XAJUWJBURhCU5a6iwT6uVw0wDNvlteh+InXWRBPDifMaMORHnOtAHoA2o6MrkgV5QtFH4bjkOS7oQ7ueGfVJzTa4VLFDYZCuDDrwki7nRCQ8LwJjCqYMeJu5q8AK4mAPtYCy8VhEIWTom+8jof6R+VZe1lahLOpkpsNdXOhVCjdK65vquyxagCpGAEJrns0GxM92KsSTDpOCfTewab2nQKF4t1FTU0aIy2IFQtyFIgtfjmZZGH72r6r\\\\\\\\\\\\\\\/x6W+P5Fkypx1rS7wN+KA6a5+ZTkTvc0ToFofMcYVd3fqWBqb+iAbr3sWYAbw3VbTa4xjJ2DmYZOFYw6l4t10SE5nmQ1PyoH18zOTGNv6kuc+V\\\\\\\\\\\\\\\/qVpC0cb+5wFfpsGvgN3s8KyOplkVcf+a5M9LO43RXGRAgTfm2mb5RNExxYSBfFaQ9AYfDiGwt1fa\\\\\\\\\\\\\\\/aQexoIiYSIAO4kwhfIRmXW0f1yl1tDHNJEZ065lva4qu4dO3uAhh1596DkdndJS3eBzR8AFzozDLmBnUAb0baj\\\\\\\\\\\\\\\/ZQ4GHINW7NOiCLeQf0DnC6fFGRoz4wRq290IumlkPnuGaAGdZTLerdRvb7N8U2oxAp7J\\\\\\\\\\\\\\\/yQT\\\\\\\\\\\\\\\/xBVQ81YjIcQZ+qra400Z0CU0se1NI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022H2ZFJrk333\\\\\\\\\\\\\\\/P+lT0hFl8NA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022501bdd4fabd84f27262b51fe3b933101202e93e72006f51070ee11e97839f7c7\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1727.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1727.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}},\u0022markup\u0022:[{\u0022requested\u0022:\u0022abstract\u0022,\u0022variant\u0022:\u0022pdf-extract\u0022,\u0022view\u0022:null,\u0022pisa\u0022:\u0022jitc;11\\\/Suppl_1\\\/A1727\u0022}]},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/js\\\/highwire.javascript.pdf_extract.js\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__aRHiqc_vICBvSio4EV9yK5gvHQhdLEYqGbyBpwrSoaw__yvqPgQIYe_eVyaoH2Vmp1uUxhQZL69H1fOXqYIpbw-c__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup abstract-with-bc\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.subjectindex\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.subjectindex\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.subjectindex\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}