{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022pTrIKm\\\\\\\\\\\\\\\/qhLElFPn+2QYNNvMoiQtsiPI+Rb25C5dnQJruF4+v2U1iWRNxFdtx\\\\\\\\\\\\\\\/pI10+PErBw+8dI5FFYacrQiqDdlRpmPZDncghhDIhVQsJ2SwAuxoSkxG7A1bwIwQcHL8BV5a+aNBppRbCKYfj7CvnNySfrSDmOOcUe5iKkc3FfmsG1rckITKL1GMMfPc7b4Fn\\\\\\\\\\\\\\\/ZehButlEnw3LijGvIX03QsuhijE3Jj5HQuLuHoln7L3qmOHh9\\\\\\\\\\\\\\\/0OTRfNI645ZuBXEQo0s5Iu+LpgZH42zNZf\\\\\\\\\\\\\\\/NVF4SB41cEtzj5wyv21SWArUU4hR+QlQmk5Cx01CegDyc1RKYbxZ20wwhzLVkP1PcWK709lUHLunKVt\\\\\\\\\\\\\\\/hvCJGwvXA+N8nb95S6wP5yV30mQK2OnIVcYa5N7TGzTMcT\\\\\\\\\\\\\\\/Cf0EvSK4okHhh5QZMy2CEOLSVFoy+qZ\\\\\\\\\\\\\\\/hri2AkE6m1u6QFO0EzJSTq8wrjgGrGs6SAZW2DIr+JvP9AGHqfBBuFAzzqiRxLQnbq8ehFEt+M+VJFRg7yu71ystxZXVuzRdDAt\\\\\\\\\\\\\\\/kR0YeggApv9PsbAL0+9Dt3RVJafOHCCac3GdObHNm8USSkBZkXF5s4+kKEQaD4TTRcGky+nGWpLyj9gXN+XKkrCWuTdeITkQbSM2IVhxAw\\\\\\\\\\\\\\\/y1DUDi2HMC\\\\\\\\\\\\\\\/mgIjgvxQIDI3GBZ4NpohqM\\\\\\\\\\\\\\\/qlPpVJb9Y16VlMu1IT86wjMgkVF+WuaLxil+W3iAY5uy6ws22OVZGXbpQnOiJagEXQ99jTHcL0RNNxkNL+ztwNu2VD+\\\\\\\\\\\\\\\/tuJ+iWhw9RfJ2utNnjozpnBIotZr06SPCOYCRk11PdFswi3MCETBo8d3w5EKW5EkbTJoxVKvFfeyLqNOhCSAQgx87nYI1IsCQRK4BUsxhtVaX+msGOdCgFGkS98k\\\\\\\\\\\\\\\/ay8h2tS42N1S88Hwap+a77JomPvLYXw4Myf75cLgWohSlv+bgxC8Dnc+v5kIN3QScA3BRmHHP6L1Qrqw1UfpZmjc1ZRO5pJX6\\\\\\\\\\\\\\\/HLfBcyzN7n\\\\\\\\\\\\\\\/Cl2iiWKFIj6Hf74+iguAbWv0Z0TwMvrV3fFR4FM3qKtyFJMTM3rmYb8HKSFHvx77AzjGgjMF8u4iPWhMRfx56qxpYRSwlIZ5UI5F0L2BnVmfVoLbxLwqGUJPFAlRXXhD6HtCNtdh\\\\\\\\\\\\\\\/yy\\\\\\\\\\\\\\\/zM\\\\\\\\\\\\\\\/95\\\\\\\\\\\\\\\/VykzOdQsXqA9FWSQd8ChGxLciDAT1KkMYyxFh6qJdcrqet4gsRJddqWBVNBd9DhC42RHx1GWwQVLVszcVEAlTuMomi6js3KTCJy56OFR7M3+nwsiHJyi6N+BXNNRgOPGpWsDHLWlQg+AQ9795miCEOzkae3Uf6KHWr3xAcJgR84vPS0E3iXNSH8XDwYjqPF5+0j4hU4oJH80OqCWxQUha4xNPprFOpfeRU8q8\\\\\\\\\\\\\\\/tUl90YUBUhTwVRYR+phAz7NiOZQOjVafNeYd+4I7XF6ShPcSr\\\\\\\\\\\\\\\/Fr8thnM3fm8cim4sn8dvTWspU5ObwtapmIJFBPQW2XrwBUGsA0ReIJqNPksdTsOh2\\\\\\\\\\\\\\\/DwWssZLVYC0D0y7\\\\\\\\\\\\\\\/uPuFz4hC0luHSTLQkdiGyYI3eFjLQhowFKMBeLpaa7K8LR2Cy3eVxmF\\\\\\\\\\\\\\\/BAEHNeNXA5rEWxwcKsWCkClJUje5fjQZAVOPlLDl54MgUFMMxxVIloNDt9lsjdIh4Pf0HMz3B6bVzOzZI31go9yU8T96+NEKSQHCHBiVH+mjv1PY+0W+HMcYs24xS9iWbPhuwAg3NUhS5KtlYLWXxq6Pz\\\\\\\\\\\\\\\/lHyQzE0LMD6zY0TnWbM\\\\\\\\\\\\\\\/SuB+MjIpQaeAOyaFxaAamaBKMw2BInCce2TkJxi9JvqNfdlkwlGTKU1cVSU6VKVQVgrXcqwjaVmhSU2N1aU8l3bV1WhkQTQcCx7OwQytjPhNkHoLRv\\\\\\\\\\\\\\\/CUsukMsNoOBx0Ab\\\\\\\\\\\\\\\/2MEHS29e9dswTS\\\\\\\\\\\\\\\/2HrFkw6xeQz5ly5eh3qOCaViFDsiKzQW3SFM+8+V8VkBdZ7MuXLtUWFFsrTr39WfKCtlkKAugj25l3h\\\\\\\\\\\\\\\/SgYsKV40jiLmob+7g8+k9ep851ZvqBN\\\\\\\\\\\\\\\/SDgG+i+qHYxn2rRGANZk4H39fwk+\\\\\\\\\\\\\\\/3FkzKkja5phZoNP5mHr6IYEdmJ4h5uB4uVoRcnvDWu89L\\\\\\\\\\\\\\\/SVliQTfqj4KtMmN4uWZ+40i4ybSwCAz7TR\\\\\\\\\\\\\\\/UuZNEmydHPM+FGQN22HpBhGr8gLDXRu53qGvV6bdJFuD05owtWHDtyfrJsTEJMsjSLP13fsi73AYYrK4b\\\\\\\\\\\\\\\/SHvi3oUNAKMAL4XiOtdf158vILswrA1Y0oY8OSlOavhNPxLqxcapnxyrobnbw+kKZilPjuNz1C3IgUXyp4F3VUgS3teeucY6Vs6GEW5arFBpvJGQjapL8awv6QtQZC+yhcRUWzwSGvjTXuha894yJIzIgp5im28OBCNApBooUnWoNkkcXvFwWq1jBXp0CilVSnsP91S1L6BAxe9RvlbEokXeRYh8WWCVCMK7hJAfpkGEdgGSa0xfRNzL0UunHLe3ULpjHhLZfBdk43SRBuMQKhzfNMcu50LMPPKDjUmvVslzexYE5T2UfRzwAGrIAkfjokxHjZcEGf2cv47qlUpsTfvHr\\\\\\\\\\\\\\\/CH+LFb\\\\\\\\\\\\\\\/8tgNiD2o0f3QTsDQ0FayYbVLWFMaRuqWaV26MODbh4QOBREkScfTHowE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022euQnx024bEmnW4SJEatcGA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022ffcb3c49267b7d936ecddb1ac074b5d39509d5c3fcd0957083447ff19644d0a2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1057.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1057.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0952\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0952\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0952\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}