{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022MyY7TjBwD+i4vrRTEWacACJwJ2\\\\\\\\\\\\\\\/eXUC0WDeJP66evCJHEKupysms5pxcybJYlkt\\\\\\\\\\\\\\\/CmcdCEFfWAdSuLMHs36bFNPxQLD0v3QkJZziWhErUFjqJokqdYoC2BRNCcCNxT7hSWYxTWf5yfxJ5HuIh6ezm5b0yH02cQViD8X\\\\\\\\\\\\\\\/Tyf8cr3bHziY2LutDloir63LyAtyqHsZyvXvykRqhid5w+eDzxQS2a+6dMzbjIAgQUZJcKdachCmLO89pRF+ghTPiCuxwgqUPGZqR8S4ezJ1BSauNU0YzqLVdjBFpQnOqH7z0LwVLf4myNLgrppvL7OQK2+Eo6ihWqZtlkYSO8SFLoWK0WkfjdDkKtnxlROZZQgEkura8FgaEjt7yvnbrgLxOw9EAe8Uiosg2gZjCNgwdqM8I64zb7Qp9ktsI2nO1\\\\\\\\\\\\\\\/vsI+e+wwIjyWDUXJZS\\\\\\\\\\\\\\\/9MkGPbYjlcGsNeQGvrAG\\\\\\\\\\\\\\\/fd80HZUCXt7XSWa7PDdWkoHFbDktR2FVAJB3vnxI5C7PVdZ0fw03Ll8BxfGnkGCGv2XL16N6Nt+0Wu7Vr60iTODZVkDuKqdDY+GYuXjUf1gpLwDeiGIdMFqjAliHp6xNLymxu7B6gx6ISvpPIOt3swfku0tLN9BqVv+D6L2S5SOjb\\\\\\\\\\\\\\\/oKuCYnvyKjMNbTTtOCJWhp1P2NpoD+AbBjWNi7VzTO1wLtojkcdPYVfUOmkcXiR23G57D01zlRVqUKSsKfTbZNKguSit4nSMal9GbdcYtcUSjcFqjSRfFQVbMjp72nBbqWOMT49j9\\\\\\\\\\\\\\\/huPEVmHP0dmeRkIyhxDxXGcqrt5utiyoPkTWUBachOaw4OfsOZ0zs13W0h2rJXkx4mbcujDERFSyJ\\\\\\\\\\\\\\\/tH42pNkzeGwMt72KDWcZlNcw\\\\\\\\\\\\\\\/s8BLKSHr10j1+lGwd1+RLC3kCPRbdQImjLh2URtLpUIceNWgzohA2bQiC\\\\\\\\\\\\\\\/NKH0QwyW+2qvYMW7SD8CkJ5suDudy7UgTV9+YNeuMxxSSeKDDBTISwENkO+v6b+NFbRRsXitse8y1Pf04OHvlFaQiNT0jKm7E0\\\\\\\\\\\\\\\/rBiyKJMLL+qBN2v9\\\\\\\\\\\\\\\/5Dpv21nQPsTeFe1tSTNmpCwWM+H7K9DoDDAuI+AetwJfGojpVcEBRWRIJ2H5msEEoCVkUQWNxEe6xrvfqVgCAgLlwH4pDqkvlnIwbyqqtI5SFRKaYXqXhtq3yXNM9vc\\\\\\\\\\\\\\\/25H6nrLazS86\\\\\\\\\\\\\\\/gxo2aIa5K5ZbFAorR+mJLP4WMLnw4aNrB1XRW+Smdcw+e77WNYFjbhZm7Bl6jAY9xzTXqshmr1drayRRFuQ5+OHEzIxbXhV12Xeox+\\\\\\\\\\\\\\\/5Dn85Os4lFBwjDNxTW3sccg7Bhi1PiOoPxr3Uh5mg4ByExGBJtB8zurBYw\\\\\\\\\\\\\\\/MSaoEV85MmDO8RVf9nmIIM45CY0\\\\\\\\\\\\\\\/0TLrYlxQ9XVye2tiY+j4t6SnEXY8JxMCiuS56d4LzOMzpYNEEiyZmOrgMAWboJySt0Dy3kimN8wl72qWqjqZ0CYISkFdkS2Txsn\\\\\\\\\\\\\\\/T\\\\\\\\\\\\\\\/sjet7IiYPzid5NrORd0clXj3BvYH1mUyy28rtruH1G4fPkgEPfxDBKhmBUbZau0hY08GsJNiHmOE21i2hVixX6NN3LPo6lCA+LWKDf\\\\\\\\\\\\\\\/c10\\\\\\\\\\\\\\\/yt2KUn02YeNcZun7QWvG6Lq82KBXXpyzGFVbFtfNK3QM4TcJhMkKtYjt97mQ7yPZB3clw60jFgRBr5+iAytnOrBvwDYouNwWx5ecGaHFYcRAqJZjTRQzt4eXSyMjMziQea3I\\\\\\\\\\\\\\\/Q5XMZQH+jw6HDqrNgwGkigoJVQfviZa9OhJThaAdwMfCg94A0sL8AfqJyh9i0ChZUjVQd9ZUanA38LdnlJK9vsuCjakgOKS73A4sHfXK7wm53U6\\\\\\\\\\\\\\\/vzJ2fqdegyzZWsip8aqmHjpAbDjfp5PmdOqUEsWQxWWaHt6YRDd7dhaROhMM8EMcO2hCqKYMsN3k+RQS\\\\\\\\\\\\\\\/7NPA4qiBvRFDTccV8Dp5e3I31Pxmhx7fH31ADCN46ksQ1sAYhIpkzgfP2kZSvORC1UxlGdR5t25vCGx2tEGAiXFhclokWgVlUTa1iskZk669+F1cP8Qed1J\\\\\\\\\\\\\\\/dp4Jz+spCMZ9WW+l2j9+1MJou7hZD9uFu1OEreZ6DVohH7kchwy88SAp9CKLYCrjMZDsHQeafPxys9P4k56xCswvADcwE34I9RQEegXHlKRD2Buw6yrrbb8vblOa90RGOVL5W9Z1z1QRB+bPPLb0rPc2NvncKeWSYvSGSiHljpVuzUTYk5VYtxsyqWQPxk4cwVMNMNTKzcKtugDgyENnpOyavIUjWGEKxRlRRXcuGNLQ0Tm2U8RcXOWepyyg0zgAcvLRYvYegh6jiBnfyP8V2ZsY7Mn+rPeHzBCcBhUOyXszZiqHCZ\\\\\\\\\\\\\\\/f1iuvKnltgNJpGVy1Y5WK6ZNKfwU8mpY3DzasA1xaUIvoLP4T3ehZUWbc3sSKxmV9bDFYyPR5GW+SCqbfC0\\\\\\\\\\\\\\\/30ye+ZJTyYTkYV6k5w+LwfpcJRpETg++YmHFe0N0Ih6Wjs2uGkVgRt9Cvsr0savavGqvqxMiS3h2BLsKTkG4JVplWCKp0YFVMcBazpMlDRMqPkJPq\\\\\\\\\\\\\\\/ogTN9F+M\\\\\\\\\\\\\\\/vjlahEiOCSsCSo3Ez9IBFJ18uYnabSp9vWpfgNx\\\\\\\\\\\\\\\/HZwxtvEVYLSU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022TjZ4RVTct5vlmT8TrWPWmA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002248f1ac8dc110f73f619513472d2b024f4b5a8d4b4dce804bed5996b92c7a2bc5\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A21.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A21.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0019\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0019\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0019\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}