{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022vUBxqE9iWzRaj3CKvCq+8DK95ULH8IDkufFWtzvUHgvrXMvwa43TsRMDGRU7u22hbrUtJOtqdJb8d5mPz5LH2NLCtfKmWtzZT88LubrE62MVoXJS9HIjKgAOQATElXsSAjznB7gDSyDvkCmpLTXTbRDugqs5GgDnREasW1hdn1LB2QhC8c83hW2hlOuk2VBbRThK0\\\\\\\\\\\\\\\/suH3TXEHyONHVt6OCA0r\\\\\\\\\\\\\\\/jb3PWLgVkB2rY7B75GCQLlyZUeJ9OmaF6f1erGjZaES7PBBL+4I6lYisC39bBjlB28u+r9w8WNtzQvcfDIhvllwf\\\\\\\\\\\\\\\/M\\\\\\\\\\\\\\\/o1peJlPKv6MRueZ7ZoJmPXVUHNWwOJQJYQvCebSKVGGAYNcKmSo1Hp2RS75S7aos\\\\\\\\\\\\\\\/3MvKc2tPEvxbdKiOztyyKeWFlgG1gY0HKQYVZu1NEZU7S4\\\\\\\\\\\\\\\/0tKzcdSK5bsRCBbTUGav+YnpeN1g0j6aeIk9q1ipNXvIHYjUABFvU8qZW63kF0LebcRonZWOkG4\\\\\\\\\\\\\\\/SJJvoWADtTS4\\\\\\\\\\\\\\\/OycFRhQeGkklGvjKZf+ARt2ooYys4gtK2oT99+JGgh4\\\\\\\\\\\\\\\/6oYMt7qWRkdPi7QnQq5R1zkzOvvJLRDi0t71aVU2C2FDBcFH9csYhovEFrYavqP5OfJj9+CmFpa0xOH4eUM24RXjUZhIl+gd975gdyzKWXfZ2RatfkyJcGNvhEvsTIHQeCLs+cNay8XMmTxB\\\\\\\\\\\\\\\/qRQR2456f9F6oRBAmaoPVao0T7tZKpkZHPOunPzIIbbFfChBGr2iT1NHFxhX81GD\\\\\\\\\\\\\\\/jRdyyO1LdzlbaGj9MfviZGQnN1IiEJnlCgoO2FMDr\\\\\\\\\\\\\\\/urbKgGfzoG9v0pTRX1JWKoeJ1PEwmVtHVGQTGhprIdrhNkwthQZ27M0hmUNs4rbTuEUW2kJzumd3Qr\\\\\\\\\\\\\\\/v2LpRaq8Fs9dO0ixnumjzBGsAm9c\\\\\\\\\\\\\\\/sa3k3InKiNajy3qf5tNYXa+SRMTRF49prjNH2orviCYdvqg7cnBWawTtGehgzz7orI5R8dnUBz20bWE6etv6je+Z88TEDHt0NBd4RJ41JXq2KWmYMcpqkvq7E1v+8ERVQsPVo5P9+CsVTyBTiDuASrqd5m5\\\\\\\\\\\\\\\/IhUPobUldyo8ZajFL3KrksMANhLEQqwi3Ae\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/ImEMZMO0lCBsjMjTvqcywYG9HKUP5VYC1iz5yPV4e9tNWxoaWo9KR5SwFELOl6wlwNhHWa7ODrtM+mIOj5nZkKkly+weoX9BsadVGgoqDWdbmVTtF8BHz90UGc6Mmz9ZT9gF3+N8OK3yszV4GY9IzkZvSE1hc5JhG3+EsvHHFEAPh+z5YR9bm71pOqxHX4oFe8epxlT0qeMFA544g6d362WRHNdrtnXIwGAPU3bvONlRXifbHY6rNxTmC7bWE9tHNGGVXo8G4itCfrY7i6RD5ym8ij1x\\\\\\\\\\\\\\\/N8aoQ5c5FsEkV6OYTCBTC7XIOA+bbAnfBXlA75SxFNE0bmR5weYYTZD\\\\\\\\\\\\\\\/QxvFGAYISSK\\\\\\\\\\\\\\\/DgtRsFD96Vuv9+q97ghdye9WOBP27ROX6wqe0WCzi\\\\\\\\\\\\\\\/FWZMSyx\\\\\\\\\\\\\\\/ojD3az2HsIv5HPt5ewX7NX4mmIUszdpnoaXNhywh4fejMr+\\\\\\\\\\\\\\\/MI6fCY+K2qcn\\\\\\\\\\\\\\\/aMBlvmMUtITP8pGUlH6AwPAydxethkuSdBvtMeBKa9wuztvUch0AAM3ynkIuPpjIxKE5udplSsq2nsqIwv21X\\\\\\\\\\\\\\\/XJA7a\\\\\\\\\\\\\\\/lcMfKU7zrPSL1gMDtpEtkvJrURZ48Ht1yz\\\\\\\\\\\\\\\/Uxqjg2HH16ryXsTkTOvfIROhM3QRirPNAFMa7aMWXT69DS651APlI8\\\\\\\\\\\\\\\/KnNVLRqJXGs9TpqTFHF6NeSkUHZffvpRJSifF9FbzvVNMMYiOmlYjsde3YMf8Qd+gKDLB9sASAhDw0Q3wcaKtBRGLT5oouzv3v\\\\\\\\\\\\\\\/LtUN\\\\\\\\\\\\\\\/b5OKRUUXT\\\\\\\\\\\\\\\/CXOm6rBcmevXMLI2l9yFa9ObNMq7+VrYMg1sLn\\\\\\\\\\\\\\\/1USEayDy\\\\\\\\\\\\\\\/PZKkJ4WEe4sBFi9zVOP1UO6vJUWjmrk1qGaBulXTlrNGktOO77k3whcwPU5XCtLFBkCrUdr7QXsCzDrewQsuEqcOczS9Qoc4XTajSS3p73NuYA1ZNVBg73s5uc6IfLJCUG5ORUPoTzt3Grc1cAcFIMiT27kd6JnyRVB8l98+ZlsBtL6nT9FE3GymWLkAXTGNJJL4FeG0hHExRbSjGRqeMtLF2MNpjTKuepMywdYSVhnK0BIPMVrS7fciHgUCIfPt69oAXNS0v0TuVMjF\\\\\\\\\\\\\\\/O7dkTOl0r4094rL3q7XRCyJrb\\\\\\\\\\\\\\\/qGKs3eI+Aq6tro2yaA0\\\\\\\\\\\\\\\/VhXZmk8XiaBOLmL7jWeqUNB4B5\\\\\\\\\\\\\\\/HiLXB+kIG2zOtVrn32hIIE6ZuyNTjkSJ7e4LLzvmv++xX1EUYQp8bP+LR4wdSIHzqIAwkltxYniLSXxBAoeMQMwh7VrKxpipDqKygvaEMt3ZfiWqZ6dYfKcDaK0ASQuyWE\\\\\\\\\\\\\\\/ovhnfEd5HB13BMdhRrKKA+q5fv9P0TLECliDdYqMBVWG1gZHs2Nq4fFXugX6vah+BdlzEbbyzl0wg5qNUvYRbz3sowR+FsYBJU2zCrmrFLhHH\\\\\\\\\\\\\\\/Hizaey\\\\\\\\\\\\\\\/zxlJxPE0A7BztQ0HBbiDXv4Vn2ELFEe+THuYwst5Ii3y\\\\\\\\\\\\\\\/mU8u1Gp6AYAcWqCTRB7+Sp44uHZYCTu1pkWBQR3nDbidp6OQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022HPXun5s3QeYeVnOpNVrmWQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00226ec77022d19d9c0e601707699e708a783130daf0215142a87ae270c47455590f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1500.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1500.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1346\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1346\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1346\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}