{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022L4IhyUg\\\\\\\\\\\\\\\/s7mgkER5Ewv4LOCMt5VFEhmbEnR64GkJefo7q8fpdnr77wzWSHFoFPYgKq37dWhBCQNqXGgc8gNOlraZeBX\\\\\\\\\\\\\\\/e6ULvnwI5tcLaSj6hYHNjoKDvVWbmDbfVgHJKmpzMOpk3Up3RJMMF24\\\\\\\\\\\\\\\/9C60woSxP2w2zRseauDl5Ln2iHlmBDIfik9ZLfr45Ej0at8hgwwmVf5jeiFYhYkgJZ2N3a\\\\\\\\\\\\\\\/lBohPtjIPalmgshwkxhFYmAEq3KDfzsJsNfDIvQrrLcwstkise2IWI2eWJhr8yRgerIQG3iSr782DsFixad3mZHsKUVAotkD5h4t1dXiQREL0f922ZFXdjoUGz1ylFdK2oDqTvBvs7E7ObuHVzE2mDdFKkJtvxR9DUNrkRypQlURBR2On6yPxnivUKWMaqGtqqpZf3P3EJqnGLBMuba\\\\\\\\\\\\\\\/n65NrG26LFgmR5oVqBwLW3+pEsy1dh3oWyRTjgluJMvrZf2DoUKX1aUm2j\\\\\\\\\\\\\\\/X7E65mFbzMO+mXHUGLDSH\\\\\\\\\\\\\\\/ytPkposWr5XZw9tCku7BsITE+\\\\\\\\\\\\\\\/lowqhOPpRz5RUbc\\\\\\\\\\\\\\\/6\\\\\\\\\\\\\\\/T1bQoTDAXm5LchpLiAhUX14RhpnYJ2g8ydQ8htX90Jy9pgYqeHKzC6PWRLSgbruWkkshKpLOX6WV9javi3K35AOhjc1INgEffU1m2BFOx5XoLolwYm0G2uqWNwpfq0eVoddUUbUrYClX7OjXfKyRiRZk13QMWtU1wvzdLD3+uXdFotQ2YvEip2ucRJ4SKanIZTvuStrjsgTL+VppXyk4leym608XKFzPVb2\\\\\\\\\\\\\\\/xhebbA6\\\\\\\\\\\\\\\/nO9T3P\\\\\\\\\\\\\\\/gqmzMkzwK1BPelVEtUMp4cm7MBAFevEVp7GNVBOakSDmSvZwl3oHo2U6No4jejbxSOL2+phVisc0BaY8CWlzVI2jTL0IST0KX3lPits0CbVUrH\\\\\\\\\\\\\\\/YJHQ7DJCDuiMb41QSrMFnvvX\\\\\\\\\\\\\\\/MrCs912TGR1P5KyOIz4lAq51Qq8qklz1on03moY0CpBmXj+C+ha6iP3nNxSdjTMo1n21elROHHtYXjipd6oB4h9bPqFc36\\\\\\\\\\\\\\\/pN5UQrECFIwI2til2TXs+JUhfqwvGumJOUXuFIThnK9\\\\\\\\\\\\\\\/X7H8mgfCZRyMWRnQJ8PZ16mTlSpCBtRWDWWBZ2dDo+DezFALS4yYtgjY7ASd2cY1Nwhw00sQF62oPnIn6mWbhWdQuCWQqsCO9dw4uvXYQL8ms1nvM\\\\\\\\\\\\\\\/8igguoHRU2bCnPNnj3S7rai80U43gYbRCGD6lYVttzmiF4cXc657PHTj2bdj7Ox\\\\\\\\\\\\\\\/3st6pQkjioos2ShzhTAQOjHVtjmODE1DhqEsGD0tK1HsMhnEIypyoUqP6mxTWXFOv33Mq0cblTZZQWF8GoVu0sxYzgdflciVmlfbHbE+2P+9NT+wM2GvWI1T7XGPLNYiAIRwIpAgsL+hQU+VANdYR+6gsvs4elTxPksRUKzKEuh\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/edfF+RUlepbrABmj3kRBwP1f+NrCk0Xqoweie31pbtuyZmpMroPJ2yHTQ\\\\\\\\\\\\\\\/jWAP\\\\\\\\\\\\\\\/jebHe4QcwiF92VSfYkD43gRFeHiThhdC5achc3Juo54PpdV+cvnMSX1Oyp0YdkjwznPZUbjdYsRKBpYZ7JP1Pwyr61Uss5gQr0DEqySnmUR4JZ+R6bG1POe3kNmDamIYV3X7E3j+IzJHVG5GnYxnH0m2bL5cAsTpCAaCf+MvzhngWPuzSCi7KCj9NgVKd0yYmYWejIzKiV0RAns6vcy+8qL0BMB7pCf1KETMGEWcNWbn9Si240LAGLicQ3vPP4OX4F6wDHxrMfBnb6ov4NBeqcDC7DnBmGo6+1mt6DziV7m7f+hG7jJcyKkRqf75oCGKM7e3Bo7EP9oVJB66tvEk5RRAtzXlaRAXnJwWaRPnK6T7vNWnY7WndMaw85W1w25VfVfdwO5WgYC1u\\\\\\\\\\\\\\\/zSI3smYBcq4bwbJuscvKWZiHuEQmSSRvat4oCr6Qafn0s9buhL+Z4V+iLORIzy7TrIIG243Pjm2jilwOOUbFcmIJc8SdRwjMcfms3cyxSUNEiNL6IjBrP019+v+lr8Z60bgJII1V8BTgENBjSdhh66D2INo6u42X56pLeLsDWj6qglvBXx1Gjpn9xysZcbNNY0wc6tEUrrPDAu3gJqADhJjlB9MmnpFcX3cf4KGay0d\\\\\\\\\\\\\\\/UA4suf5G4PryoopMSacGvzHD9YMXwAET4onvsGw74xf3Xml0xVExrdLOaTbl7PR5HDXOPJLqaV07oCUt54vBgKrON3HhR8CuN+vDdFKARVAp4PulYmgNGIK8qTfOLrR36nnw3ZsMjw4IoPB5TaIScUjm8CvHJinF9JegAYI8s2nYUPbIb32krSTOedwyWW+KF1yejxN6XgH\\\\\\\\\\\\\\\/zrJLsR84KJ36m1VVlu5Vtk6q0S8Rp7njnH2lnB4AThlWckcmnKhT0+NB5FUgIzYzxEOM\\\\\\\\\\\\\\\/QzArzLqlGDD+1O+fIHAnJUgq1kRjPrjhp\\\\\\\\\\\\\\\/0VWUrogq4D5MJgzEeOcBmSVva6uhQWv3bUWHGwO7pzS1\\\\\\\\\\\\\\\/RJGfuLTxmfEo39qQjt\\\\\\\\\\\\\\\/DF6kWprRWYAzH1t3KK4LWFRmpalaS4PLUm70muXZhkEniPMF+56x4nggE5IyBd7dqQqU\\\\\\\\\\\\\\\/VcjfIhtdrQec5HqmSNaxAERL+sLYPQ2K44sF9SHJE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022wVrtK3MgEV4p1Nc5DmsiaQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022bc00f2db175f7b96ce142bf1a7e156f9c1c3fea81ed21df3f78926b79872f794\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A508.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A508.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0457\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0457\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0457\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}