{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022lVU5kAPg24trnLANWkKaQhN2iM97Ls4o5YvtcumDbtdlcZI2QlhVuax9ZMUNqlAVPBczZlczOxHkc6IwtQ0Ul8I4QtOskyBjRVjOQr6cM0zkjYYwGVWpraRmNbKHzR44TxaEKwkBbBJ\\\\\\\\\\\\\\\/3ISpogI0qfv0P6vHLoOsr49sYgxSc450tDGtJGv1qem7eTbkyQfo61qV7RFzFR9xJ9SWZUbgn+7WPOj7iviJxKdLiC23j8Lp+I6HlHeeTXQ2VwauxJ01AlUmd4rKZJ3hoHc3Rwox44QNC9XAN7ZIvDF3ZuR4Jm2rVLFSpdOKI5HVKy1Y3dwqZuvIubLQJeX9dk8Munuv\\\\\\\\\\\\\\\/eiOezmyCwaIi4O2x5agJIfF522xSAcVWoVQP3rasePR4AxT1xQcgi5ZfP2HyJFCpy83xSnzMl9iUbGA9xD66ywrRuCXgopzbTAwElzz+ahzPhGUy6h7n8nwPmnfKDrKuQV+TbBwMiT7pddF3qQ+yoz8glEv\\\\\\\\\\\\\\\/3Xyq0xZpvA+EhnFfFvu4TDi+InxWxG8xNRKe5Me8PMBlnwYkjwQJSTXItZbD4gTXyp1mX0VjLx0IAqoOd9R7ekGUNPXtdHEVersszAdAj3Xiwok3d9Ma6nYZ0O6EHb+1kvn04NyDCv9SwUtlSrUUajvrIg23hhBMohp9HYGOWYC0xriQgh0P7b157+PtB5RwayVTfrnpXFbihOvqWnnf9S4wfVzQbAeoHVCEOwdI5FxZHCpt7p8dA+G5C5ovo4fwoTSwasZ\\\\\\\\\\\\\\\/h\\\\\\\\\\\\\\\/tv2zlRfkITtr4Rhvn2aHP1pB\\\\\\\\\\\\\\\/XDgg6aQ0SSh3iRjJ2bkTnHUIdTG\\\\\\\\\\\\\\\/XYP8U4k9V310N3\\\\\\\\\\\\\\\/IBUVgLpXzLYabRP7qYHafqHg9RE1Xrfy3tCe85hENssZXrEYhGDXavUTG0OGP0mdBex+mf3rVLCeO9fevR9QXaLYuCRz45Sba+Y+ah1GRmrkmDe0GIFwHy+BpvmrafG2pxpJk5d8mMIuE6tkffRKiqtZR17nQ\\\\\\\\\\\\\\\/rotinFnjkwXJcG0Y8rH2AjtXsEWE\\\\\\\\\\\\\\\/MNJFmCFsPQwZCz8Pp1dyfl4w62HY2Rw0hYxqNs3a3xv8FTpGy3L1M1IZOiz9ypF2hzT9ndorL5YBgkJbWONgzXltsg0eogC1oqcFdiHQIgi4fiDp1gqZTtKXq4H3XgV3eGEMlGH03qZSKwLtVtbWXfpp7m6BeUYKF5+ThMuk2Ys0wO3T6UBknBXx7N33t06kkOl3JNBXfia8qKapgzdDJbNedQSflomFnvPLQzx7IVWvYfBdAzyrXFaZkc2mL+c0psyTg7x0yDMuNk5SMMNS1PxoV016NBfh7Mf2EXHrks\\\\\\\\\\\\\\\/0HB0wFmPogWTI+8BLrnrF9C5O9g49lhZiIFEJHzpTOY0s+zpJA\\\\\\\\\\\\\\\/lSyjO2iLzfbNShxW4yDdi1+vECQFVgjUkHT4nVOvtZ8i7mQp4DZUlPhbFcDE8jsjO9b2Cc0ygZ0AkoJbI2bOVsKKcVZvPJlVNWlXfD5G7cjAiJQP8Yq2JB3Yfy+LX914wBp0TEs7qD6iSND\\\\\\\\\\\\\\\/Ut81UhgiAvzTW25qldXXK6t8RuQcs3iDwt4GOs0yQTOuA0gjOn2fz1y3ZlCnIiY5FQYtfNYIMsl6H4alHJNwqmVAjWZ2cSdfPDPFeNuoiGddcBwVhvPSOMWk\\\\\\\\\\\\\\\/aHQfHoed+A2AVvVWLy1UtQKyK48oGauagn9jt\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/hb3spqIAhR0iPJFa5hIbojbaf++hooAgk3A97X5q11\\\\\\\\\\\\\\\/m+8gLV4dsxdzRA1tXiJGI4JTQih+\\\\\\\\\\\\\\\/rh1wNCXHjA\\\\\\\\\\\\\\\/D7vTcDqePsnPEecfq\\\\\\\\\\\\\\\/wQNnLN3BlkPmmxrZXpfgeDPZ1vW5h8oTByVuev3OXnpU5TBNXURGj1VGAaEgurrXIL4HnzwRD4kBg3K6Hj2WdeeMEemTSahC+Jt53zFSjCdAZxPzaUFx0teZSR0ZIiNmmp2iuniAen16CrMbAl+X\\\\\\\\\\\\\\\/Bs7VIdEhKOtJLyjl+KdoQ6XSGGP7JdKhWZAbiJF6Ua7YANvktZTLcyPr4wFDkxU9smeXZ\\\\\\\\\\\\\\\/eSlujVqWTirSgeBsHCekd\\\\\\\\\\\\\\\/gLxUH5JgMIAzl+EGAS2iRpI3GHV85pP6t9vl7Sv++9JYQlrwSkNgV7ejoflMJUtSW+OSPoKdxmChhAHnz5sEe5p9cVvOPq1GvW\\\\\\\\\\\\\\\/uvLkGT8fLGJ1OLXEjozdKNdREIeMlX40t6bmK9UykwmEUUy3AFrMPy7IBaoxUPJnrgXtoj9lIbQocQaL9A0+aKuuqqu0Jm0JR8kf\\\\\\\\\\\\\\\/r9DWb7X9VWo+YOj45x2JnNNULRZPhOIU4+kLdbyhZcKY27arZJ+IOmO5qZJyzfrKZpchFjRU0UNH9JwOiS1nv1zKMK8YXc5u\\\\\\\\\\\\\\\/ho8ygeX7OJiYsxD8UTjtOQ6sDjlQGAhmYVJSf0OrnOjYtDAfU5OMSRvOo98y+7u880u7pE1zJxoA20S0nF6F+4YCycTbceE5\\\\\\\\\\\\\\\/spDM77PnebqlUuGna\\\\\\\\\\\\\\\/PRpze4CI8mrt2Y8oqDaer5eh\\\\\\\\\\\\\\\/k\\\\\\\\\\\\\\\/5wtQuQw7BEcEDgsI3tPqneOF\\\\\\\\\\\\\\\/01zrV8DIOnLySlF3gX5GYc7lEaHoqUm\\\\\\\\\\\\\\\/YGHWCQ3zR\\\\\\\\\\\\\\\/9krQFIl0TLmG0QCT62CJDf8TnWxtzhGGgRhiWtyhAz9yJwIgEHdDR\\\\\\\\\\\\\\\/wQ6XJ+POLKJAVE6IOzfNotTLrx\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/U=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022r6tGJUhAY7gsmXaktCPYag==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022fa78cebbc9ddb3485e4662fd84559219480d7151e49f79c91cf1d579aa7a9f1b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1237.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1237.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1124\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1124\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1124\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}