{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ZDNM9VknQkzUYAxAgaOR29QOcZGwrQVCbBQP4qQyjXM3kwPQNzyRfyVffu3dbmuN21EfnRqAr\\\\\\\\\\\\\\\/9mjeL4UQ3cMCGcQ3ljg4rX+PjUKz1hqkOzhYL44Jh8UjHQBbzYVglwTzZkz9unb8AXNTSDy4EfM11GZSjXjtixS9u98lFuNEiTplr5Piz3cxIYfy7pct8h54oyZzi2bzzEc\\\\\\\\\\\\\\\/v2UvrQ+GaESXXwzMmPRU9y3GB5EQv7cJBP5pJg6twZymmmILrkSa4oQiLj836o8hjn2QAPNxy4PTamQrLZwPIA8Mylb0tZ5UUF0Hyfe6WfuaOu3D9AEzCQEOHK2DHTvoFucX71lKIcWtSHMDODUqBGyNv18omphmGt1\\\\\\\\\\\\\\\/pTowWgoyqbxz73\\\\\\\\\\\\\\\/wsZp2KYNrsKX1ALFckVt+ZgfuPeyMQrFCT2WSn2zNPA2HnHRGnzPbrKO0QmngKtQ7GavoR9tj6ieu0aImI81O87cSItng7U1p7aSPe0CjYHZJzzhO06S+sy4t6\\\\\\\\\\\\\\\/zvdfWrFzBjeeC2DVJWp96cWXsWXFRA\\\\\\\\\\\\\\\/OrWxfqZvzZTwKuyeLBiuitziv+8RVfezsB3JjabKd7neLdf22G53653zuwXJqHJdWr8HzSFkRyLtgVD6t1fnZOHJRhPA5LkTv9WRBuQAJCXBwcT1aq4hTdJp9zVEt7+1XgY0m9XXPq53Iood9gXUAG2rpxYncR3uBS\\\\\\\\\\\\\\\/xyBteQcNrY6m3WAVTrv2MKfjCG3retvQlYKZDA\\\\\\\\\\\\\\\/JEE1MNmvoILTLG7CIR2D399cChAUVxykJHyNkLQDJ2ISb3tbwflLVXzYXS\\\\\\\\\\\\\\\/8cqxG5js0prdlwwHDcJkbZYGmkT1KWWa3NTmPXPR9t8YG1BlPIXQ45pG2TRggT1htQi7F\\\\\\\\\\\\\\\/xFtFYkHOv3ahH+gC7pQAAIJgqAh3QwZyn9fJ6gj\\\\\\\\\\\\\\\/qpOQw7FRgsWL\\\\\\\\\\\\\\\/V9cs2SzY33e1TPbSSYUZFDCdxCo3cQf9hY1vvVIoUKoerwcoafrC0V+a9sHSCFdAzEYajDDKjHrK9qhFnW7Dmj5STyH1Qe200sx9DmhuIJXl5HExhCFyO751FJGV97fvPa32IFzfqosPyjk+5h6TNN34dmpr7X86DsHASEXq3m5yxPE\\\\\\\\\\\\\\\/ohKFh\\\\\\\\\\\\\\\/xcpkw+LOCFHJ2jMpmROZuO4sYpdSVg7bAO7xwX5KNN17dO4YXuM4HfuVAvDQbmYQlyFYw23fo1Ttw9WRI0KNzs6Lpu0UVqPJgYjAqaFjK4FQLq7vLUmbysGuKXnYRxgZerGagZLhJaxNbWdn8BQloOMauaQNL9ADgwZygIhwaa8pbWgq\\\\\\\\\\\\\\\/hcaIPbq071GKTAoL5OoP0MgVdTvE5ArESsM9VpXfl9i6XNJ7Hvu4Wio1H4eQ6MzpkVBZ2nfo56kHLat4\\\\\\\\\\\\\\\/o2JCYFh8\\\\\\\\\\\\\\\/Hy3OM6\\\\\\\\\\\\\\\/2w7+1rof7IFYFfhpgSYdkfWdGaCtAo49u3oSSVu\\\\\\\\\\\\\\\/J5P8boVy32lfj4x21tCrTQQGLxiWnp4BDedguRJY2MloHFxg7JcOwohVAF9mQVD5hSEBNNwB8DfuEWMbmc+IWy59WdDLjP3nyQEK5ADds2KFdg1o3TCJSjPBbAIzL5rVtb6dKgZkU6v9R5oNDiWu\\\\\\\\\\\\\\\/vgn4ycLxR5I9gqHn4VAWhpqVax9o9RmB160\\\\\\\\\\\\\\\/wPbbEJ1BjrC+VFH+YdetWfCmcRmVfBRbjUQrBc+7auIW3fF8Hom0xQNfKQeV7W7F2d59cI4GX1IJiGuUYKzBUvWlmD3qoxmT+h7POeKD9crRYt9JeezRgfgZbEty2zWdbeAr3iPZ1rexoNRyQynbl\\\\\\\\\\\\\\\/+S6HIvbIf8sy\\\\\\\\\\\\\\\/+NTw5TR6KA8V5KzAan8P7nQ4GJMHo8P3OPB6V36Ns9ErXCffKf4DknyeP9mUwxnSAG\\\\\\\\\\\\\\\/J17kNh6dQr48dJlMOcNdbeyFtTtue7QB0rlQ2\\\\\\\\\\\\\\\/x6gsTkDrhcuCrKlrMgGTkk97GhoDXcGpEw\\\\\\\\\\\\\\\/hBlcYznAXpWXikYGQUxvT3v3QLNGRPE6nx\\\\\\\\\\\\\\\/9DAcK3lw++g+XyxtRMq6CzHa9TBCrdmpGSvg6fbrUZRlaySGbgZntIIHPaur8Wmv+gF1CZ+uRyzVcLcBDXRrpVW6hybS2KvNMuuHTSC4\\\\\\\\\\\\\\\/JroPfekzxVA\\\\\\\\\\\\\\\/ruJaBldR4+McF0dctZBwJ5t5TDkvFsxmiqvMf4TA7KMbfhaEZmLtFqNKITlikFdBE\\\\\\\\\\\\\\\/FY9LmnbM8W1nl8jsBVn5Kqzio9pcrw2qi1GlgNcxmXk6MF1niFm4oo7+O9Xi3Ues5NvK6p5zsM3lbJ\\\\\\\\\\\\\\\/yj2q5ontroBWzJr9GjtlhC1UQx\\\\\\\\\\\\\\\/kCpdZyN7vaBt43mWMlgiJBE5Llyvh4e3EI3hETt5CS4wm2z35beeZ1IIIUqN7KUPUpFPbls0VziFryebiKuRt15XS0dvQ6xfOR2shrSXGWYy3l7PAUnKesyfmqzQDK+0GaU4IVr37HctkpKKBqRZkjVRlSzgZmkkDMF8FPvNUe4OawabW0zM1HFPgR1z5KMP8cTfGeiHRlfDr6xVzeHa070+rxfcAATVbctrlgXaurgiA0xb81MFiMH0I0sd2dZq63h1R751FKpAkAYQRI\\\\\\\\\\\\\\\/j3x4oiAy\\\\\\\\\\\\\\\/iEVzvGv9H0mo0xjmNE6d\\\\\\\\\\\\\\\/ciNbhSwPaMuRdpdYEaF2y+zKZAzobOkoHKwbRvmifmqvrtkE1ItogKGtJCIRTnfIhQU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Y6CoLLU9ANNnLQb+qu8EYA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002241d521d7549be018829eb6e29171ecf5f63c2460d933d7a6364fffb6240c103f\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A18.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A18.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0016\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0016\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0016\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}