{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022w4a5qZFKGXCFtBvbTxbXN56GaqmfcJP2KTkRKIf70rvfXsxOnMprOWEWXHw3EdvFmFY1cWTdW64uK6nl\\\\\\\\\\\\\\\/BrpscQPW9sezm2DUI60ESIKV8NEwQKRuqPUx3CB7mbVScf8G6P9n75pOtYZA+r5JFlZXTNevvGDn89pS6eyJXRDLUyeEskhtkbmlav\\\\\\\\\\\\\\\/tyhP78H2FO18r2f9cLBVRO5d8Yj9MvlxmYYTe10TwbOlO96U5HLPE5HFh6nWBqu9hkRhAMn4yqbJpdAgHJU0nKuZ9OPp+5xmKKpSj\\\\\\\\\\\\\\\/zj7NUvPvkyhGjnO+kEY1J\\\\\\\\\\\\\\\/JcsFyjmuZGE\\\\\\\\\\\\\\\/Jamlv1\\\\\\\\\\\\\\\/18q8gtXUPleGq0s03eA8Q7d3NdDdCCbCR9DKU1lUpMHmhiFn5oUrn3XWq9DfWRkBRqgwUWYN3Q0MKDVd9xz8lzGh\\\\\\\\\\\\\\\/AYuZLCmkE66DRSh2cGm6o2oOoL1dslp+\\\\\\\\\\\\\\\/e4bM6DkHr+JHYl\\\\\\\\\\\\\\\/Fqbl6ju4nH8wLsasLfple8JZpw8LfbPwJFg4vdJpIOa8mxjhSBJSZQoc3GnLNw1TsPnTpiq8QKsAA3Dvh37pV4GmhVM\\\\\\\\\\\\\\\/m1BKDUziDzD+FKqWYE3Lh0YeI71TFf2ZDbpxCfZSf8ouW3bNiuIVkN1b8qclurRoc8dO+H9U5uX3whwaw7+tEUYCbLHT9xf9TfjehNFMzzLJpuCUqa+KG3Yw1XWoMl\\\\\\\\\\\\\\\/Mxt7FmBr5aKN8nreU9W9sHOd2iOuQxsqJV5tpGfYr5am4dyVuL3X0xH6m5icBqw0onBgqmYE3yF7k+kl1exPGGgEF5X65yW2Tzn+TSlNwChBWu6H4+U8MmCKLs6CMXjNwQqVOUny\\\\\\\\\\\\\\\/by68t68zxYDiR5scxq8nXey164iirWlNs+ZlUN2gUdDfK03pnSCcRXpyRe8lS4kG6oJY6gs9ze8X+\\\\\\\\\\\\\\\/HYMZi6aPnwoHwQp17U2+Q8j3RIyY\\\\\\\\\\\\\\\/+TDFLxy26\\\\\\\\\\\\\\\/YRiFUaQlWcqPpC6Z0eB9psljC1h6KCY1ix1KgoEtkd+GdN26ksvZKUloE+EudIIi\\\\\\\\\\\\\\\/orHJBAytyNGKElvxAtkqtQeDLCx40B55iZRCjyN0t0eAQ1nWv54016VQLFTKuM3MCjWdQm87qvHs\\\\\\\\\\\\\\\/aBOwpDgsr5WKjIqS9pr+ECdQ2sGWZf0Yy0uVi5XBrNtphBFSLiVyUUWSyisMJySeIZpRrbO0K976+Uj\\\\\\\\\\\\\\\/ynJO94HfuibM8lS9EON5RD5mHMB1pHHf2xOYJMQFxJmlZiwkN8A7xynB+hmeHyWtu+sJU8sKar4murr9TSJTAvFW0mbx70Z547lrwbo4yXiJFqJ2F0O\\\\\\\\\\\\\\\/F12aCcupdMnu7fv+0LkuCmI9bxc1pzLP7egEZtGuXBxaVuzXhWEkppNs4xh+4nyYOMtWmE\\\\\\\\\\\\\\\/7XVuUPxxHMhvBz1CyfUzjhwjwR9DqcRFo7Kz7ykplbJ04PmGoEdcYki6uBjVzldYHsV2whQ+ol+56OT1MWOwCxSneUGtIXVn4JPzgSg8PlKqgeD5x+iKYQcpeUYNaPRuov82wSPhAIHTT7JTT40TSCu276OLuZD4gV+nDPCsvRymsCW5Tb94okSjX3wWJUcVoZkaizOhh\\\\\\\\\\\\\\\/yz43Nvrg92OdycMCX1GUYhi78ztP\\\\\\\\\\\\\\\/ium3ObhpVxamKzJ8voEEgvkz6K0\\\\\\\\\\\\\\\/qUxRlR9bO0HC4glVSNobihwtVDOU\\\\\\\\\\\\\\\/cu8kQjvP9rwoDmdBJGCaWLlZEC7oohmKhrlQglD9X\\\\\\\\\\\\\\\/1owqaY2FQ4PV9lw3H59t8MVHCcHDAd+afChkujH5ETobvpllksJldkXcWFkuxRBK4Mgt02uiBrZlYNSr2t6OMBVQMKkM3BAnaxlaR5BG8gg\\\\\\\\\\\\\\\/DCfoNFSFqeCnDQsn9dtn8uBBplsQ7d8p+gF0Rvx+4+9sLZd3sySckOU45+v+77MEsxnqldwi56DQwNv+jPEXEvh\\\\\\\\\\\\\\\/P\\\\\\\\\\\\\\\/CQTJllOaXsiTDxa\\\\\\\\\\\\\\\/B1B5qKZOsJWj\\\\\\\\\\\\\\\/qe0KqknpwCTZb0qTrr3uyIlsP4tGR95opiAKn+S\\\\\\\\\\\\\\\/sIwpppa6dwGITk\\\\\\\\\\\\\\\/EsOkoKjBUACgnpRa+KeFmzVtIN1fNTgsd+B+ibyhwlcxZI8zkcmfCgtjSx\\\\\\\\\\\\\\\/mi6LmfnmK3Alti4tBBToVz13Evl\\\\\\\\\\\\\\\/pJGzcNsnuA4tQv\\\\\\\\\\\\\\\/dOvhi+PO\\\\\\\\\\\\\\\/17Mj54AM9Gn6qwL3BtxzBOx8EmWt4OH5V0\\\\\\\\\\\\\\\/PVixRuiy07\\\\\\\\\\\\\\\/Sn9+X4RZFx+iF0wbYd5DAGNndNF8bovSWlMlrSOOYLZIXEh2AjjgcGfz\\\\\\\\\\\\\\\/ebnuMk73IK6DPztz+IQV0rU7QKdVlAN44GHoFf66hmSWfhFetdBDzxe55xu81Sr9BU\\\\\\\\\\\\\\\/FeJD+wm2j\\\\\\\\\\\\\\\/hyQPGkR2KTkylh7bkOnZ1RA1qvVaJfh54Y0P1XvFUKLhfsKoiqpJLlHKFNqkihL5js+ykHwOcK71RSfW\\\\\\\\\\\\\\\/pTLDk\\\\\\\\\\\\\\\/Oo6CVTdEc+6XKCg0IYhnqxoAoiBr\\\\\\\\\\\\\\\/8rTVSNvYYyhMV4xhFIXJuSUlLw4Lt4CVBZWcMgsyfhnR9K+d4VjFb2YCYz788GM47judQO76eW2XJK1\\\\\\\\\\\\\\\/aZ5gngNvJ66sNvUDudrMATWUkxSuBUjBs6Us8\\\\\\\\\\\\\\\/ao3rWODt7Bskgsymoi4lCR3fBbR0zUXEzybR1YhD5A8EQ+cqiC+xUrtLEohWM9QT0JEO6jeiFIWXh73jlz5\\\\\\\\\\\\\\\/zSZEbU5vEXqhs06FBWMi8an7Gg6XamYlozVA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022zEqMCLJiU78g83e0w7AQbA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022e0204a6ae6510b2f532b5442d73a63401c9cf887c77daea156086ee3a42bebf3\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A321.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A321.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0280\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0280\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0280\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}