{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022J0T5i4fCCMiPHbPGyCOAkPnDdbBBSmZqauABNa0oa9esbF3gOYMABgzR+zulOfeoH7HwfANKzF9X1VnaO6t+\\\\\\\\\\\\\\\/LojG7oPhDoZVlOBwKrwBzVDMarjZZNsOSwV7tdiwjUlj5+GsyY\\\\\\\\\\\\\\\/MZeAlnHhrf1kvFoUDQX98YV\\\\\\\\\\\\\\\/6\\\\\\\\\\\\\\\/OM2RxvndAVfIIJe74naLeeu2nyc0DXIvR1sIyDpzcqe94WpJhl14MjeCF4GdoO8Lhv96+P\\\\\\\\\\\\\\\/bR1saOdrkL+ldctD9ir\\\\\\\\\\\\\\\/TmVYjQEYiHbUPbN4jfT1KU27fg5h0UkB4h88sHXsSD3lvRiqTSoMHT44\\\\\\\\\\\\\\\/IJ4otQahLCDfllBWc2NrsN385r6u5+ynYNvwv2uArOB3cz5MoP4uaF7ANVa0l8nREZZNnsqnLzflVppwfx6r\\\\\\\\\\\\\\\/F05VLUVpo1EOXylldVmvPNqJjR75WCQDIJpKEf+BePtIegn9DYJCsvlgqbzGTcag4YeGgSW3iMB5s5WRFI91LGeryz8+iOHBiPdS8Epl2+s7ddxyzPS6tB2dHl8rWalr\\\\\\\\\\\\\\\/cxS\\\\\\\\\\\\\\\/pJ46VJNBHrlyau8ktMm+O3ZJ8WPF6ryAju6jApH2nukYCkCdlAOwYic8p990FP6ONM05lX9oatg2ChwUGNEwlOwtaoGa5IacgTgAcsgprRwmxbzBIKjiYGfZSU5VhZO46IH6YC88lc60Kg9yL6oNUgXIDF9XJ+RJ5eBXmD9RERp5k0vOefWZ3otKdQkDUzP3EsOM5fenSWmTbLPJfKuk9b2k1EXV0MfWYWefB9ExY5ZkhejfOvf5vPIHwf5PqcAp3j9iWE3qhLVQKgXxV6XQTyl0t5vY0wH7ZvST2TZ4Z8gXYTzedoM0q+VdbGmKF\\\\\\\\\\\\\\\/cemqi0TSO+DTQAG7\\\\\\\\\\\\\\\/+yCYXmGNqsmYo33PWOGJLnrR0qLWfxM1YLzd\\\\\\\\\\\\\\\/ETt7C6TPBokMKuZ0muWfJkLLenOW6EIho2eTYvXn7X8Q2+BR23npZhiowABPXqJmmEgEmw5nC5mWJ4jX79rQ3V+f5hlzy694oxOY1P3XYYn0OZjFv3NAFU1Nezvn8lbsHnThyQEpyt5h1BJCiSD\\\\\\\\\\\\\\\/W1+3Fk4jtzq1QEyt5itV1JeiGGx5sFHpBb0LoavwePCtbrZiU\\\\\\\\\\\\\\\/5P8atUqUvA00lTvgfDQPeg8Wy\\\\\\\\\\\\\\\/vvPyRAseZ\\\\\\\\\\\\\\\/sATEAZ0DPcPnYCVhQtCC+jfJi0jWk0yRWHf7lmbYZ6Hb8umUVzGMAZ3oV1g8TUphbgdQnbUiCXjm1OSooAw1wGmn8PXxOLah5ESo9ovP4KavPsFzRpe9J+SDVplINUms6j7xBaH\\\\\\\\\\\\\\\/jRV88TcNB2aDmvCHED5Q8KwW8pRgngLYVGw1dpaNkGxeYHNSjrSIWviyWvc5w+s2P7O+pizeEzreuFOCgRydEdH3\\\\\\\\\\\\\\\/kY8eZkph9xf5lerI\\\\\\\\\\\\\\\/varONN5CWxmssPcEVfSoHpHq\\\\\\\\\\\\\\\/HyQOuiv+erqJrdoJWQNlkOSZEtM9D9UMqLjf8UiZKMtcFai1xjeWcZS+at\\\\\\\\\\\\\\\/9207CqLijVsLRAguugomjLdIG3I5\\\\\\\\\\\\\\\/sANo3vn1xFPzcOGaF2HG8IczpyxcVoXHWJZXXkzAIFIDLZe8+GSThx4kRrOEy6FCrEVhtyRqoG0OExygWckpWn4K4CWiGwP8l\\\\\\\\\\\\\\\/FkRl2Jjma16TzAxNwuxPWCCDO956pCAtam2ICcVb0pOQ8UuBEq4cB7rPn24xU4f6YiCIcl8LU4ucn+2U280fmTe3R1lKZnP9BnmI1ZKdDwd0BErR85MaDsbKu6yVXcW\\\\\\\\\\\\\\\/UEiQR5s05bZDx6SlSV94J2cmnNmPa9K4JbhjwcKCFh4pGanAaUl89GDj4759LQOV0scXBY\\\\\\\\\\\\\\\/O0Ss3PCJH0xMds13IbgCjdBcxjWZh7g7eKEh3RBX63bO3zOu5UNeV8syPpUuL4SlqyERhqS7q9u4JQkipl2la8aODK09wTgMDlgBTiqUQJ3m93rKa8orvMoTIWqWCsCqO7Ec13TBotFIMA1cprGfnH8GVFLYJjIo6ne3aXjWKotayQBJRVWqgfx0YtY\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/9oP6M2IDszva2Huoe2GY+t5gmNz3qoKQnyMJvZDm+VhcvH\\\\\\\\\\\\\\\/xsZzEi6RvamqnXK4lz25tIHiQjgBjKnyhq73aIEUD8s14+VyghUTacHB\\\\\\\\\\\\\\\/PrS89y7yKFnwVDSl+spJ6K9iC3sZm0vSMoPzERyF0JQhrYk+363TEnS53w7Jp6XvWUGAqG8V3mlm2tct4zY6zLDIpUKKxVugefa1Ah\\\\\\\\\\\\\\\/vgqkZWfehQYoUCYkExSF5DTqs6h55tkt50libxUKJNfX3TYh1JbRo8BYOoF4C6xQMpFBZ0Y9G0iX7xyCBXkfSb6sDdktc\\\\\\\\\\\\\\\/xsv7ZjXlDzl1dzrTocg3WYpczR8q6gh2WFI\\\\\\\\\\\\\\\/dBJiuUfkpEm23DkdcdVMJ5q4HFuyJ4SHaZd9hdZhgOJGXg3hROMYimEItszIanRUPtAhegmNX4bre0xmOLTlx\\\\\\\\\\\\\\\/sDw33n7nImhABujOYgr85YPFQGikasJqY3or2EFAG1P+a8WEn8XaY7PVcwYk\\\\\\\\\\\\\\\/h7cEauR9wDgieSytetHT5XvKVaz1caQLy4a0ILnfpBy\\\\\\\\\\\\\\\/JN3A716RMKrP+a0FUNcy7IOIzEopGLHx3cFcNKYhZ4yyN7cOCNmu\\\\\\\\\\\\\\\/zfEhgnKLoJfMrBwY5gZ+CuJ1nEqPxFdUR7ASjZHTliWdjh0=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Yc5JhyzU6knYqvDxaZ\\\\\\\\\\\\\\\/Skw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00222ad2ff02a6495b91146b0d73ba8f86128054a3fdaf6dbee799fffd0fa62f043b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1430.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1430.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1289\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1289\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1289\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}