{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022tQEQx89vgW91dnSaqFzFo0EIir3idF3AE0Vxpmuz76ONz5aBw6xjuU78zzy3nYeWWqPdiwHGHTTxqjpBnxC6Ahj93TrjKBTy8w1KOHd4f1NYNl\\\\\\\\\\\\\\\/b4xcCPNnC1cpLz4+MenIFIUIvd8btXrk7npUTQcEHRkMDEqaZsSvSCBF2JRQ47n6ZvBAETHq8iWK7JOt2YDVRdnUF3IAKdFvth0EPfE+2CTrKECe9rOiBwu1fy7dK5tG6M+oiL\\\\\\\\\\\\\\\/PWe1p728L9tQPJta9V4wZVVgJbMfc7\\\\\\\\\\\\\\\/hxvlnA8GplAoN8l8KbNy4lL87sRWYBMw+PWGHr7Lcvr+R\\\\\\\\\\\\\\\/0TFW9Uqd7dE7hQjtHnez2n07hIqhIqHwtPKWEPTNDScKDkAc6CBQvqvYe0LIuLlUJgdNfiPljbO8n9fNeDdeEpQDIRlfTUFOWqQEVW1kxHS+sNEarcd+bnTkmNDdII\\\\\\\\\\\\\\\/5LWmTQS5QLOdLVTobGSnvSY0gOboSiIcJLuVXT90rZmh7bK0vyW3TPPyibmwYcgU\\\\\\\\\\\\\\\/Jc3BpcP3p9rd1QXbCI\\\\\\\\\\\\\\\/9FGT3QjMu3sS+zihaL32ZFGHMi+NngWcnZ7wwBvKiCRasBu9LfAdiRmGop1qENnWqNoYyqTlrBHWFHgtxvzDiAXQhJX9PqFe9THOG3p\\\\\\\\\\\\\\\/yklAvQLi9PBED8PrhAHJWdB1LupXWhkWWc4NsPvTlfBf0cHE\\\\\\\\\\\\\\\/Cj5bD0XPlA9CEOQMDYEXm9W0ovvC48UsW445FdWB4GcGYGE\\\\\\\\\\\\\\\/Qzqxy5gQEt9RTX+kgTTabTl5MmkE8CnsKYneYrNa39kgmK9LSSMCe0aqxi9ly\\\\\\\\\\\\\\\/Lwt0Yel6T3eMdfPe4YgVaSGgnngr+LjRaZpWMwwZKW3iN6VC6wo4dBTpkvsR6H10kzQlt7+N8Y\\\\\\\\\\\\\\\/kiPjp+0QueS65JcrGm3Yjb734JEhwb4+eKnsrxLp4sJUuiX6DZd1X0r69mGwRkbuF47B3k4Ocmw0foRAOAlCH6mumeb1mNTO4bvCdkHv0v2T+mmwe1H8SekVAroaYKzBM817SHh9eER5uicmzloBiQDwEQmlorAjl1o0oxseXvnKRLQPkpe71rZ5ajd4K8t\\\\\\\\\\\\\\\/liKF8GNp5DLvfa+0RnBSuuqtiP+XzJ+7QkNkvNqPJS+X4co7QWw+WbZ4k7W3mvCz7D0jPHm1UJCIFMjlwWM2s1Q7Cmz+\\\\\\\\\\\\\\\/Yw9J\\\\\\\\\\\\\\\/QwJeo5cEpzrNuuEDVww7vgytmc7nR0tNj65efS8KynHiEwOLRJwX6HMxgyjq5CdPmlqSmn8eWeA40CdXkhvAFze7ZXAXnjADVo3Ec\\\\\\\\\\\\\\\/vLI51FG1+lDHdDdkZUfbuRv4Mf1J0m93pYoEtJcYa+opvofUAStXXLBdaMy23IGByLa3r28v\\\\\\\\\\\\\\\/lYNw88\\\\\\\\\\\\\\\/PaQ4fncoduXLjkBkFzVw8Ve7lyfPCQWupqjbijGb2vDJMyZRfve\\\\\\\\\\\\\\\/uGHicgiU5SYGoyp2bL0Vb1MwmiY+4KOOKWN2CV5ZCmt6A\\\\\\\\\\\\\\\/6anOh1gM6ZtdHAVqmW+Sy7gmvER6A\\\\\\\\\\\\\\\/Fos6cYeiXWjz9zmUQ6MPzGqqtvYuSUSZI3u9jm2CllGqz0SK7vvb956Za7S\\\\\\\\\\\\\\\/ctB\\\\\\\\\\\\\\\/sbNQO+4svPie7X\\\\\\\\\\\\\\\/dcqdfz7zr1mgxwkvYebxYnruLmtwXzxC4JBSnqZdX9CMAuDGrmNHx0pSTQxi\\\\\\\\\\\\\\\/jwTnfy1xAkpYOqRI6RCRmItbGxRX+oXxEFARixzPJU3UkyciDVHmPBta0U\\\\\\\\\\\\\\\/wysP3i8v\\\\\\\\\\\\\\\/iWbxHVFxJoNz9S4qz+rDQLSmbcOZrRpEv\\\\\\\\\\\\\\\/voPAfJbNAKcPiQ2zJ6hQ9s2ZnvjRfFJ3r5kiQGMIvCwlEUSkKTLIfx5baEc4eaW84pTSXCjwgMWCa\\\\\\\\\\\\\\\/m1VbZlrJ+eVYiG1CJSGzzm\\\\\\\\\\\\\\\/xwz9azhSwH0w50Ke85Coi7Kh9rgljLf3bG6Vl5PXeBCvw9Ihequa5GBF3ZPCQk+cw0gG9rJ3JiXy2SLw0tTfSLcdCbzC61vLPYYhKJUFsZhu9r4we6+ar\\\\\\\\\\\\\\\/PwhaZY97rn866EHW8GwdKw8MOMjJtVmf5dCYya03rAanSEv2X7Aa1MC7WwBBPkqYl5tqmd1JPjsENy43JuXBH239Wu13C0ruNPsT2uva1LhazKe1CFFZ3BG4mOKgcJ92VQEfX1Mqbiba9e+CSxxxZE5FrhnLVN+3AKBMCuZxNUF0RoPLo7nfvxNwCtxl1caX+Pwd63jwjjvEKa59AkTUhyFhBxNZqT+5xgPDQFLyFOOHPpTfQNbB\\\\\\\\\\\\\\\/sFddZFiKMkbsbhzT1iE5+wSj880atBgxQPGO71+mwjCkZwi5rGkSGZys9YYhQcUXkYssxx1zsNbbbWMYbgXpwuCqUCHmYur6c5przALARCAl65ooDjiLJWAWmJEglLr5WX9YJc0olEnkV+kaYrUQLi7XEd1TYI91ndkYTZyJhm9CJrUmUGNYqUnHpqtHqBkTY3hEKIkfgGUZGX0oKayiXN4VVHphfu\\\\\\\\\\\\\\\/f3gqDL8426waGxXkHouKXUVthvF8xLhMRxadzYiy1ikzF9Ya7w\\\\\\\\\\\\\\\/T75KkxCPp13aYQe\\\\\\\\\\\\\\\/HoeYd21\\\\\\\\\\\\\\\/X4QsJmj7buJ9tmzUhCeE\\\\\\\\\\\\\\\/TgrLhDvk3td5UhZcm+sLqi9mNJ9G7hGbqxMHqtPZSnHMQYFgIONSj9TsnAkkKiz2pLPmsBFMK2WYbGdJcnLSNupU2U829WmLv0BfL6odTk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022xk2dIN7LaCrKctBn8CLsQA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00227ed53593529af9afff95fcbdd65b4d26167253d98dd20525e43a95ea6db67784\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A836.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A836.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0742\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0742\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0742\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}