{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022nTFEf\\\\\\\\\\\\\\\/2\\\\\\\\\\\\\\\/8zgXGBEoOhybi+TXNfye9PTaFh3nUFWDCvmcIOgGhIbVLGDzN7ubyN+qOMDX1fkQYq4UwUvFGxPTj36zbg1k6\\\\\\\\\\\\\\\/8zgd5DnL8Q3znahbxt\\\\\\\\\\\\\\\/+l6eKgAABUUfNmZpFWWUe8eZHDVH5FPpbYRQCcP7BQ3zUi1HEWz+vIenMmgrHKQgFhSTCswV3RfIQDWrOapmqjkxP8a\\\\\\\\\\\\\\\/Ew6zhpr+CFON3A4elgi2tUdDavV+6\\\\\\\\\\\\\\\/qaS+oyCcDMxfNa3JaxpYaNMeKVIdcvrrTUv8Zpmxsuy9NaEMB\\\\\\\\\\\\\\\/WZgQzdM4GLyE\\\\\\\\\\\\\\\/v9lSIqNAHuIQbBxbiRwdjx3dr6taRL8DD\\\\\\\\\\\\\\\/fxqZq1bPe1jyO2pJQd0qgccsD\\\\\\\\\\\\\\\/RQ9euAWMK1kGC67bVuR\\\\\\\\\\\\\\\/kKyGgq0K\\\\\\\\\\\\\\\/CLTXeWAeQ41EG14pkZvYZGaKnwKGtS97YpWklJX3f+fEMtNCSz54Lhmg8b3rP4pfFvBkkriKBd\\\\\\\\\\\\\\\/LV+\\\\\\\\\\\\\\\/5dsu5UzK8j1dPAX0Ijwww7uBZkAMmJ4pOgV88T0qw4yFNNMXDPz+A9wrMeQBZea7icp2br7EWX7z2xU93j44fXoq\\\\\\\\\\\\\\\/U48VlMeL57CR2woDiwGwjV1t5J7iNI1r\\\\\\\\\\\\\\\/RVnsoLQtIpOpFyTy9zc2C06DpkwnMUXUqBgUKIkBX8\\\\\\\\\\\\\\\/KAlCIBH1Rnyajq4j0XGvWWiRvCOj5bay66hyPMR+s10CQWA35HRmsHvUToeASJ2yjoK0V8Z0x\\\\\\\\\\\\\\\/k1ZpGa9dBpvp1+f8J9yYBKBMCJqmHcv4ZWGV5qRQHuOU+Xssoi5anQU0tx0\\\\\\\\\\\\\\\/fkerpE0rqg64He11\\\\\\\\\\\\\\\/Ue1PWJPBIr7urUQiX6BGmjQSZKkcMtuASfrwlNdwV82Z3yr7FxupxIWRZkkF0OK7aQO0lvPRpueb8wj0j2CzkTq1Ny5ehDnUXxbfopyUtcJxtQpjpaNJsJTnjHyXoBwB+7fttGzydstM+pkXoRB7CrCtRVz08cecnrvycoVSWY44kwLsRFCVhpH0DPCIa+HfhPmm8o6L\\\\\\\\\\\\\\\/NhFpSReIg2Iri7U00r7oQ6\\\\\\\\\\\\\\\/8OrXUE5ED6dWyTpt\\\\\\\\\\\\\\\/sG4I\\\\\\\\\\\\\\\/uVB7EhoRw5nOqlMAhF2PAwrJlkmpFG+VMqK9S8iCjuIRuVxYM5SFrhsZo\\\\\\\\\\\\\\\/PvMBH2hyWnTYSlkNEGnoOmACx70il2jDOCjR7lwxUSI6NEV6ziO94IYweLRGtW+7z27ohjKDnh6zvsv4pJ+XNyIzNqDp2mzQbEnSaXXC2x5LH60G77wob5rMTPEZa7QnCyTXF1bd5puCne5wPOZ+hRtCaOzYoy9AP1W5zGi+G5BivcZ8ANJ1Iy8gG0dZnsdkhEZskS6gOOrN2xUyZWQ3Go9soT8yCL0L22WIUf5w0GgWlkO5X5ZAHLoddG9L6MAZmjrjWjfAU5h9KG6S+eql8wAsJcgqSu\\\\\\\\\\\\\\\/xFEcDF2h2aHhdDPTPahHtj3MJoEQG8MCbVUiq9IlxNdJuS2uIZCH3gAwZNO0ONCkNVmZCWkWBV99Mh958oHinqWKzbY3N6KOkg1NuRh9etJG31ESqAah6fNyTssoDUUGX+VgSTCrw4OcGxhaoNGRE0zVyIWqeNZJt7AF9ohTC4lsD2Cc51YhExBDU7otvEPY7cBZ4axJzWDF1YGOUTqpIDioP1zDCM7VdAznNlnR0OZx8jsWmbC3RDhGriuTNCmk6LHU8JFa88ntOJTn66bB4ylqBT\\\\\\\\\\\\\\\/VllVqwUDC4Z1MxGjNRrJDPTjiEA4HLR4G5yQs3eHlaV4mAiLK8BKY0tMmE0ESQXe+q8oyldTMH+Q7RDz6YAG\\\\\\\\\\\\\\\/8I08F54\\\\\\\\\\\\\\\/e3sHbmpZKy6n3VirvBlljre5CkPngiP0MqVhGMFTwvqxLntQ92NDedPOw4CFVR59RGIggCpE6YmrrG7iuWyNDmeR7S9q+dw45WnwmYjhU3y0bDJGKFMrh54kdW14ctXSLGwHXz2LpOUxz0tz1cNWz01daIWbBrXSMidexJ6Bjl19xtpA+jGXhoFisr8WHkrIj6J\\\\\\\\\\\\\\\/0+6dKWXRXaGDt\\\\\\\\\\\\\\\/yWSHMgA09LSrX60HnlBmZKMUm61jIbWWOSVD\\\\\\\\\\\\\\\/GJLh7WA1weJiX5ZcYWkLr5SEjFJd+E0c5lDe+zNmxIs\\\\\\\\\\\\\\\/FW35LeGSgTdi0o76y5Mk\\\\\\\\\\\\\\\/GoRBcid8VpB7CrjR9eLo4eXeb+meURLFR1ReKviM+XxSmiEtzVcAzNI3KUmw5H0PwKNNIq9TaQx6D\\\\\\\\\\\\\\\/u0FWt8a7JRFQvOeLJ9II6daWYUKDf5WGuGC5RRr3shl\\\\\\\\\\\\\\\/GOwV+YaTu7+QpsZGa3ZJUC4MfNErw+\\\\\\\\\\\\\\\/reoikV8r2x8bFESFwTws28UbE1+H+srQigMGsqfR7uzlsiEEMlyLagrKJBbVY0eM81oFKEkeSIyHtFBjIHrYMqyKcSlQzCim6WGrglN\\\\\\\\\\\\\\\/42SpmRa85EJ5F7RPw7x+HvKrqHoJvT9LRpcxRSXjjeVd59w4VdKIgdYVPnYsus3SMtrjnGIQWnbDT2Rpo4eAxBTBYbYQBPtYdNxGl9HzbzgPq\\\\\\\\\\\\\\\/Q1zpl5Xa3xc9T3j+JoRG6x3dGrT\\\\\\\\\\\\\\\/5OPBG6IOqtJcqnpJYHPDSWdV+Y0yvDGOcBZyIlQANtdR\\\\\\\\\\\\\\\/mGI7NyzoiZm0DE\\\\\\\\\\\\\\\/uNetnrnp3atcniV01jsharMcbobIN8Ha6JoN5M8N21e8Z\\\\\\\\\\\\\\\/WppVQA0hehYKTxtacpcbZ+E9pXH3F7mL2OcXlJ+Co=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022J1gcXI6caEiqSjG2aysO0Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002209659f322e96216e7e4c841544f74e57b0a431296258925879d78dae53b1a366\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A551.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A551.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0489\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0489\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0489\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}