{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022hADUyBKHItjyCQS9QWV0EOJkrDhJu0W+3m7Cwen6yX0TQYs+H6NH+O688YijWP6AaGjKaX29t3JtTG2vF7SXFBxsGfv5eYXkuWMquj62c2k6wP1IjsASOxI5y9OScEj17iKHetrif3Eu5sfDUxCCVjMB8doAgBooGryJqJVn4tPbromEunskvlLKb25wCbeYfrTF824n5oVqv8QhX5iTZR2k3Z+qe5Aaajjp8sUwEdOluX\\\\\\\\\\\\\\\/Qiv9R0fWQUIScHXA2kaCylq3aPnZ04D4IPPzvrsAxXMsUqF1g+c2WjK5QhfzKNM4o2c5IORjpzfyNg5owDwNohnmrWbWORIX4gPAVb5XmF2N0s3F2i3n0CDscyu0\\\\\\\\\\\\\\\/ihpc+cgmgG0JdPdPYOvI7MaTiEV\\\\\\\\\\\\\\\/1TSkUPc3n4cZYR4BzYDllzz2bGGFe7Pa6Ul9PtXUrV2Ms7BXzkp9iHhvWlFNAyn5y+5F1\\\\\\\\\\\\\\\/nMg7hSyyh4dMYyhlT84GyJ6nsxL4esXV0Rsz6uzR6GtH7DA3x8o3zD9MwC5dta2dRt9nnuGc+dqAUdCvnn3Arah6kFeJaB32hLJLLK\\\\\\\\\\\\\\\/+aIBmp+eg1qQ1N6Lcp18gYep7TGAHMbXgjH1wHQ0CIZy83vo9lJmof0DsDxTVzGqL\\\\\\\\\\\\\\\/m5J937rcp8e3imVx4RQSm9raGuNqf2yfjCN+A9PqQYUCzqssg58oN0wA8uBv8Oc2XhI\\\\\\\\\\\\\\\/mq5cQw8rrBVs\\\\\\\\\\\\\\\/MjxvbAoGo+e6EEXrQuLDZGO0T7HVGj0HigaEWOPsc+\\\\\\\\\\\\\\\/1bJx2BQaUthNI5LLJIyjNk+d1hp5mGx1hKDffunNOvi0H3X2uwoHJxyJKiZjaOYVk0BmakkS+M2dLrWkoE72q9t9v4DIPPqBmjtFyvD2vNZORO3MD6FIIDTlEhNiv89XeDXrYuTvHTIANxjAnJd3dhnR59V6T\\\\\\\\\\\\\\\/LMRASRXYvsE50DhIwewx\\\\\\\\\\\\\\\/wo8iJ2e7c0Ug\\\\\\\\\\\\\\\/vhjIr9VCXFNMjttKtmvOdS1jUB8RZIz11\\\\\\\\\\\\\\\/ntHryMUeWtqN4qiPGP5ZI2N9XmSpJqhK62fZWImE6C12+Wc6fYLkd7ZNzqiq\\\\\\\\\\\\\\\/vISOecT2bcPHPbnsWgXfY6mS7rGc3v4AyUf1n\\\\\\\\\\\\\\\/f5tSdEwCUMeHgVkVuqtXSj11F49mK+bCSCS7Q82QAVj7DcftUKG0gVTSlz169buvNYx56HIBhAXcUn1eOlpotsodEJY9QeGBAuhLshSPUpA8o0XjRa9ZLgkU+Pj2rRkzTo6wvuc4ohT4r+KUBMi7jlUUoN0h2GWcfy5UZUsNgA8nSKlMzsBUfVseJNIA5qQ1\\\\\\\\\\\\\\\/OAzkEQHsR4yoAuWdRVzan\\\\\\\\\\\\\\\/WPKYwKPEe1p4YVCv1KeN3PrZOGd1JFKHsTf+UhmBOa8PPa+Gg5ItCFL\\\\\\\\\\\\\\\/OVFu5QqGQp+ag5ogI840eFlyyDXBaFR3cWjCiX+Zz2ODoKsJw+W+qEHrN7xjOTvbfxPQWxrie1sSdRu8sVoGTo+GC2kE7nUm3KhUujk+Zc6f0AACNEhcNED85uc4UPRN+DH4IEzOhmfGAAKvRDFkDcCczDofIzEny5sLw0IpnZFMiriYk0fokC+0mascEGnQlpEXVmzsbrk6PC\\\\\\\\\\\\\\\/tUMWDGYMXUpU\\\\\\\\\\\\\\\/ApXmrNqZz5HO9mge0K3RndXTixJnG3bQ+tjR1hJtqhiM9mK1qIqbJ9AtM0xH2ugiR7YRv1nDPL1EU68hq7+lHl5V1ruDQEOS0ktuaBF2Xz9EGEQbO+1y6S3bL8VOYdQJMsKBLNs0EtDp0Vq6ac0STYX7A3KG76pJ+ooEJMKKx28Esn\\\\\\\\\\\\\\\/3N7Ovnep+cFpsBf2INh3fdrY50oPOAq+XGtEb6HaesCrvjnF85hq+PTGfuDGkOqj03tpadn6kp97AcaEvaYdKcGMiRlt+7\\\\\\\\\\\\\\\/NujTyCxwDeXpBdJKGINrIMUD5TWDGf8ktim2KivVr7ddhE0xqLOWHzwv8lEy4c+APJRw7jWxm6+BJdhpNBlhpyy+Qa8FXxgcVqGlpYH7iPEKhsOA7\\\\\\\\\\\\\\\/9F1lGTEIFUAquw5z0z+1LIG182AwG6\\\\\\\\\\\\\\\/nT2SasG4X675x55zuzwbbn948qPDaEsVKRfXznRn+9ACHmzeGQkneefXaq6\\\\\\\\\\\\\\\/fAMzNpGMwm2wyjXoC8jqwTEzP\\\\\\\\\\\\\\\/2p\\\\\\\\\\\\\\\/POTZO3R30\\\\\\\\\\\\\\\/vSKhx6uGdD9CxdTEjX7iFKsVpqHqwjVy1b8\\\\\\\\\\\\\\\/4Pnx43PqOkDWaRigfWNWNR2+Hbv+0atlc8I2ZsDJQWkHJhwlIVQCKHdZ84UE9dCMfNzVukeZjnCsoeoFHgwKvBzS59eaa0N+IVehpyCoJQ73\\\\\\\\\\\\\\\/2m3I6iY3EJmH6iQH9BcFOuHSZdd\\\\\\\\\\\\\\\/3\\\\\\\\\\\\\\\/tnQREZ+w3jqaJG\\\\\\\\\\\\\\\/kL1LvgtTrR1kcPrezx7f8R4pcwQoNMY\\\\\\\\\\\\\\\/FMrMKpap7ufeUqwPUC82L9p1wLsPjDfBaBZf16SjSU\\\\\\\\\\\\\\\/U8G1esAE\\\\\\\\\\\\\\\/M3kFrMwgdy40k7ClLVDm4iIDMKLtqFzn7NVtfAQATFwTfg1I9s0QwAdf+YiRPos7ZjIs8rllSa6stshUNxzvrbWQEVQlTlONerPgx5p7oqyNR+K1hpPD1LBU1ziXMTGjhSYGhnfWsDa4Mt6AXomvTbbM59Hc\\\\\\\\\\\\\\\/S0oyiMzV1qD1TLCLDR1\\\\\\\\\\\\\\\/Kmcm9ovkHWjeS\\\\\\\\\\\\\\\/SxfvcNl0TkNQ+tWhRrbrzTaY0ClQCO5tbprVhVBA9RC3a2X30Ul4Q=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022uaKHKMhygUihHIOMpz3+4Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002256d49de276a74cf72b2b0952adab1d4912e903d55d948a80e1716074670796db\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A490.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A490.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0441\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0441\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0441\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}