{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u002204rMoNW4v4nrQHZUNw0IYLmZc93IhEV2Tuz0timFVS7jtIDPZdBCOefanSYGM7H7L6kMe8H0\\\\\\\\\\\\\\\/vC2N61XQ64vPBqqWDVK4xJCs3axN9YXZR0qNBl0EQveYaMcK3Xw\\\\\\\\\\\\\\\/HH2u0Bnwi0J4rt7H6h7S2hXlZ0+mZqPjPHHRLMYl5\\\\\\\\\\\\\\\/AmpXPNfzzC\\\\\\\\\\\\\\\/kKj0qxZ\\\\\\\\\\\\\\\/qO0ruicfFbHaX\\\\\\\\\\\\\\\/Esi91AKSVRxZGdvfQxH18zG3NB5OTkdOsw0Vg0aUOAp4o0BAqIOc+I\\\\\\\\\\\\\\\/eOQJWiyl7VRN19ec\\\\\\\\\\\\\\\/9erk2vifM16H16yN98c7ez18LDsPR8tAEo+6jCrZdcY0Wk8Yg42LrvdwheqbHrzO9jwuWnr4M8QXISUsyEEDIC1Lks6LsMHRRGEFO+oOTSYfXAvbzEgk78JPBVf2Y1Olmy7ba7axvY7eGvYZVqQaaMkp6pzzfmT5Kh3qCZ8Zj+JGi9urwBX19TPeIbLWKjkVyCREX9AkwUZHg3I71TRUpvHd2T16979ddeF9fYfRdPazlOQX\\\\\\\\\\\\\\\/Z4UHYPIX2ecIMOhLObWeiaJju66kQTQ04mGDa6IFNMxXJRD6hCY+YFOOo84Z99sToojhnhethVRbZDxMxznqYzvJ9D5zL2FaJEKFvGINnA3za6P9DNAPmmFofsXphmWCIkDLdNB9B901onx1PGwaXht4hGqnz1BeStrZKuiU\\\\\\\\\\\\\\\/s\\\\\\\\\\\\\\\/BPV72z5TN2xtieT5ALE7mhbWqwC7K3YmeeVosYWleOze\\\\\\\\\\\\\\\/Rioqp90Hmu42WkguMWPx0vNg4M9Vw1Gr+8jlc67ftL6yOIbaUE+eRLjjiiwGdAywCqQLkhqU+TuVJTQc7dsiYQ7ajCB7OoZ23Ei27GHGaIi59YCfVUGZFV2vQ1euV4iuXZmlj3QHOeH7090rPPkJCmIJoRJ9r32i3awxHeh+WEqhf6+BIWw3GajJBaCvhHpRvhYSWJkhBxBPrqqPCFEfdmj7o35xQlaKF\\\\\\\\\\\\\\\/LGXvFv\\\\\\\\\\\\\\\/slwXXw\\\\\\\\\\\\\\\/5o3wQxSNz05q+5CaxlZ6r8jzWarD6LWS6PUoXg4f+kRdEOQhnAOVtB4g02Iz0XGMBUYsuSUtjKU5utdE9g7DULs31hFHbu9GMvuw4F7DYcAnVz3VuC3XDqXsVshpCWdTLwpjBG6tlr7k9tQIV96dPhTWVTrp8+l0r3krtjX26DyXmkYeV2vpK9OopmcT76938W9IGseN0utb1aDTVM1cPDmK7LdZYBXQbYwqoGYAA3J3RnoQpvTg9+Rnb9+w\\\\\\\\\\\\\\\/6weKxfoDcxL65y4YqtXZ+jybH6KoG7j1R+hSCi4yFWkNBu2YyJTe3IuOx0vnzXvgp9KYWq39R5mmvuttqqSZVfCp7M1dnzq\\\\\\\\\\\\\\\/b2rRc4UTwQ+lWhUHFmbvoY3i1J8+DS42NM1yL0zoOz44CmnUPfT4LBhZSnxzBdsh9Om74qIarAnGeUnDeZC\\\\\\\\\\\\\\\/Mq58lKm36TJEhnmib2XE1c60mM6xYhtuZZ30eLUIQvPyBanGdN+9i8zGun\\\\\\\\\\\\\\\/R8qYunb8+HbcLCKPgzY928c8TBLM2MO1OqQN7GadRHgJsycASxb0DN4GEyr\\\\\\\\\\\\\\\/LiVrFFW5w82CTJngObK6Dfn8rdX90SRrn9x0QILG\\\\\\\\\\\\\\\/zvHzBuB5QlgbE8AfPRegAobYsrqW86hioy3Ud3EIxNnKVmo5Z5AJvpL3FFOYaB0FOqSZKgjP3uHqjeH1bbsg3\\\\\\\\\\\\\\\/PNLZIFs4FLdXNhy0302rwMOyNvflYZX9nCANv8zas8\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/fpnzL5387OYIIRo471+AfYYxhWJ7KOXdrOjgK2Y+q4zOtE9qtuyXP3lj+zc5JX4X1Y4f1gC341FfoJA1aA86un956QTB0cfsds+HoqhHHGXEiyygV3JWvJtcEMstGevRPYxMMf9kKpzvPhJMYlzx\\\\\\\\\\\\\\\/7\\\\\\\\\\\\\\\/RRAxXWQWD+2k6Gu5CxUt6TeiWt3D+Y7jSoVke8PGCudfTnNwLpI+WEvHaauabICOQXu3CUR0BSjyZrfLq1y3X9HNVrfu5x7xnQLMurCpA3f3CHKXQ4wYAuJ+YFDIIA+C3oMeNLo5gAWhknhzLbno3JSzwOY+8TwP7mUmXlo0M+XvYWdhdDnuq6q48jBB5SVypIEV49OExdhX7Mpt7ZkGup2OCRs4Zsg\\\\\\\\\\\\\\\/iX\\\\\\\\\\\\\\\/RPngqsS\\\\\\\\\\\\\\\/6ZXn16l81xS4B+dqy+vyyIRFp1QBfWHl5ZNkbPGNt9oKZo\\\\\\\\\\\\\\\/ZVtaMmepFMn2XiuZz7lW8mTc310tjWsubS5SWyYzG2HYnTf248KK9s04yaqde5RrLO7HzYfncrgoHWG25E8Iksh2V9LHR8jTXX+ueD7+JG2hZftxRXqRrn\\\\\\\\\\\\\\\/881uOVhuDk6YUNQA2l6wbn4rsDKo1IwTFK6rX8jKsNhiDfcTE+CgArnitWdY2b4IC8U7XbpLPOBsnwx2wyeU02LaG5zU7xfFuczmM88O8qhvC9tsX82OoBPnEJaoaJe4Fap0VUjNnCGVo0E80qtlQDakqP0D+rmKVYNpPVh5UlwK\\\\\\\\\\\\\\\/MsvUjr5mgYLtq2xB7mKmzly2EPPueLrUhCa21P5xOBcIERAWNui9M\\\\\\\\\\\\\\\/0ZG0mS9z2mXbHsOzdzhPmqGhaSLXvSsUfDCRSmfdepUzlAX0XzGRTNO31RQ+9eXVUH6iYXjqie9wVYQa645jm8h9mnXDXn4nMqCyLrtcczGDRsWRE4CjT6tQoz1iPIDzb2YQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022CWEkYv1V6BrkSMdzk4B+Fg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002290a28be65f26e3fd87c8bbc07c5b85872667e3f5439400985a7d47ebc45ff92d\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A757.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A757.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0667\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0667\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0667\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}