{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022djaPR2m7fr7RnGvxm4Ki9UwWElycJPS+Aofx9FsE5Prh4fjr3qeQMQqsGc+DUqD0xWT97ND18cqvdPAwFEtZtf31Mx4dWn8iyAxg7R2gsPyfMmYg6iq\\\\\\\\\\\\\\\/gOS5WETR\\\\\\\\\\\\\\\/wrCnLQlpe1DY54Ddv0VuSTBNADD6z0SRONmSszpIdblsPnx9o1Yr7oN3AbXJOIvx4HlN6gx\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/yIcOtCru4wuc7U4cuLRnjQWjfBd8do3rMCP0xmPYsODLpUzzcRX3FYC14cDF4Ez4uhqI4hY+Liw5BfKD7sF0rR697r7CWz0dYoD8ITFmDnGqLvGxdWkk+T67\\\\\\\\\\\\\\\/x\\\\\\\\\\\\\\\/VfEOtuHEU4\\\\\\\\\\\\\\\/LNYQqPuAmZQUECRoeQGS8rswKR7Y\\\\\\\\\\\\\\\/Xu4JxKYUzNhSJ1ccvJA7cRUuYiMqTMkACkyxS0fcfSQhYJR5X7d8L4VHBm+WxEnFT4F4cZ54WgK1wbd6bBw7ZxoumAjelhzDV9TU\\\\\\\\\\\\\\\/1qWGall3SCXtlkXrms0MFGkfl91bANNH0Mm\\\\\\\\\\\\\\\/VuHiQNYTWtAWdSOMENPZW+p3SYS2bCmC4F1lYByjO0x27owhs3VphPx3Kmzd89KAU36RxQCnaeUVr2cxU82cwGSVjEvxVflzg6sJqEobR8lEFha3cPyS840IbFvYHNeLA46geCN3TNte\\\\\\\\\\\\\\\/kWX8yfwsMTEZ2BKPvrFysP3hIgZznsjgBiD2DGI1jyVhtLcv2iQ8ql3cJdNMk\\\\\\\\\\\\\\\/O72wcCNn5wN1iQnCX0Qb57ntih0UtyQ9WoNvEdWIZ7\\\\\\\\\\\\\\\/r\\\\\\\\\\\\\\\/pql7LE0rNUjIF+1l4sLbhriTzGSk5YCvDk\\\\\\\\\\\\\\\/aNsYX6RhiSkExdb0Siyl9cDkiai1cMgTa1XnkVkOSBW96NAs8dHsl9MJspZNDL4ctJ6EVLPpMZXL15n479r9YFxS1G1e3mMbudF8ObejoISFM4FDQhrWfdWyyKNn\\\\\\\\\\\\\\\/jHycg5xUgvfh0CB3vUHSSXFz4jmHNJ+nWL4R3LDiso3FRO1guhQ5pabilPxfp2X\\\\\\\\\\\\\\\/33N7TzIcraVU8hWZh8nOecZL3yGkGOKyrY4Jok1XBNS8tfUw9JIBtZ5pt6dftZzOGOxBikhOl7GATQPMrzOOPkI27cehiQw\\\\\\\\\\\\\\\/BhdvgyhWxGNDgvYxaFhPYNxSm1xAi7SkfS5tmFK8YzCrzlZkerK5u7SoDPCvnlkT7g1qvJTOSEp7aAKOAwgrQlxGWdJ8PIlGJflQc\\\\\\\\\\\\\\\/Tkws6FgJ2ZAE9w11r4nUcqC\\\\\\\\\\\\\\\/mkADjUZ9f8Qw\\\\\\\\\\\\\\\/RfPKnOO0Zxf+6zKPqagg3EWB5mUT1uE7SgexJX718xzawDG4n8txPGGk+Ng1vvqcd8TbsP8qQVcmGdzHq+LjHp3mx+VRJLNVWCyfbAd7rLpyfTMcCfdvY5pCkn\\\\\\\\\\\\\\\/lG1\\\\\\\\\\\\\\\/XYxlICB6d9gsOZjwmBZrjCw+pgwUNcoF9J7\\\\\\\\\\\\\\\/t1VC8GXig11vqlt397I70Dzzo7wnXYBSZdTn456e9mTnHvMBnbFpzFxnD2By91ycBUIAUJXd5z\\\\\\\\\\\\\\\/MaScjY9gDYZ70PL1+h8N1mwfaWC63AEeEMAbUveOFMz3wZSPrXVS+jtKor9tL18vk+zwDXmT+8xUq37Ruv1au6DibBsibV0xwLSYwV611pZbkNvtdxnwZaGzFReMwS3HpSPQDtyEvdcgLDoMDQWGu+SQxUdBUCpBC6PGHRrTcaxUyCHD\\\\\\\\\\\\\\\/TWGyY4Pct0TuK+6QF5cWUnrMlwchB0n2IAs8lW0ydrbYQseUnJide\\\\\\\\\\\\\\\/o3jSWA8o3jb9VFnYabFIB3QZyUO9ghuwO0cPv0M6IYpUA1WXXelgSV6ACDSCSN0NIvX7uu1d4+I5e\\\\\\\\\\\\\\\/7LWIoGWIFwiljUKIB3omUZSHeacVcRSHl+5FIoAbfWfLEGofzIFOHUim8zPxo40VDXy8emIdm6qnem1dOLUxE0xD04nGc6Lj7sg2GBTno0CPGfshKf5PlOWcD\\\\\\\\\\\\\\\/snNvmmQ7wd\\\\\\\\\\\\\\\/ti1jxpiFJWH+UsRLkk2D+7EiGJutfz8Qi3U6p6ytLi1tJk4DrWeqMggBIpNs7qqcJvVoHUbUhaoL11IeU0o5UWk5C0x9H1bdLarl0YOF3+1hpTEOVAmDllfqbSCW1r5uz4y6WEkd32hg5xYqVrOlg4RB\\\\\\\\\\\\\\\/Jubqlhz6K69J19WX3wrDJfRRUsNFNA1jZ\\\\\\\\\\\\\\\/GoSKdvQG2DWi\\\\\\\\\\\\\\\/NSBmQnbzgW594wRPx7hEPzCNaCLf3L0l9s4Xpb3ME6R6etBgSOa5oDMiS+jwL5O9XI33PE7d0F3fjHzXrgrpNKL1cFcydg58Rif7G5l0Kzz77ZBkPvKk16qb+W90raOAAALTKbWvQv69n3M5DqXfbz\\\\\\\\\\\\\\\/nH7dYBwBVDpYn6x\\\\\\\\\\\\\\\/WsYZUKxPHyXHXXOk2B9QmP58PqadGfmWrdKmKU3yaaY2u3xZNj3Zm71wgZz0fb9HZa6JMj\\\\\\\\\\\\\\\/sgD+z8GN\\\\\\\\\\\\\\\/vFGu\\\\\\\\\\\\\\\/Jy5CKTy+LzUgygZVIDhBFaL5CVG9yVbdHGWrTKWNq0kXAWZv+MRuX7w8fmgPCyKzp3HzpEh6y61OMJHfD0VH+2pgZoHv8HanQyKs\\\\\\\\\\\\\\\/kvvlV5jh\\\\\\\\\\\\\\\/qXBD4X3oEAeX2cAqNpYnYruCpABS3uIa1D9yt3QqZ+Gz96bK4YBvYkyj1jNvVGJs95TzBgI9xsv7frjBKr+texsQzsPSToZoP1GrbS\\\\\\\\\\\\\\\/jfe7GBUOVKbUKXsABvY\\\\\\\\\\\\\\\/vKatVPbBIs1XdYQZeoW7QhuXAZ7qxtUn4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Fe6fpQWbk0KNLijMWMpOoQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00222783667da63225b3074628967a6f3031530c6553716dd909ead6d31b6a01d9b5\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A698.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A698.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0613\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0613\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0613\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}