{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022mQnWVAxEfbPewGWJA7dXg37vuTf3Ha3oG0IbASq4n6Zo0WHI3XEoi7T\\\\\\\\\\\\\\\/bS86ALRY\\\\\\\\\\\\\\\/DfeIroQ7Ukx+rsTm8G8stR0SEmmcIwFfZyhLwbv2SMXtcQBBDy7wsvedd4sHfzAKrlWfHVc2rOPSnXJTdDBE2DVPYlQCGajlIu15d2\\\\\\\\\\\\\\\/20tpzvQ4MVsJPfKNuKROEy9erWB9z3573SI5e78p2rJzciCaAkqaBo+U2pNRq42O+3HfXN\\\\\\\\\\\\\\\/4uklQ0kQRGgiaY3EqORE1aLYcwUqGqeHkQWxF\\\\\\\\\\\\\\\/EvqbafUijTfE\\\\\\\\\\\\\\\/TCMDn4o26uqgAInqgzqszOPq2HE2NJ4s1uLnHOSUOgHvWAZmsRLw5vzRLHA9d2BiSkt+yhovqgqFtPrVNv\\\\\\\\\\\\\\\/ZK66AH7CdZA3M9ugS9utMJQiKZA+aYcKoM61U48eEWxRyBGJtZ1gF8OCsaKgOf8+7TJoYmYzfqFXaH\\\\\\\\\\\\\\\/F8iu8G4jEk1vb55MIMqnxor5If\\\\\\\\\\\\\\\/tyJc\\\\\\\\\\\\\\\/uBL7w8ahAaAdBEeMFLlvjIzh7j5dswlmVcv4s07xg\\\\\\\\\\\\\\\/FxzRr\\\\\\\\\\\\\\\/lC0g8Gc250jbJhS9fCXgGxkzpEcJUe3ZKbl6byfLcF6N9gUDPZVkXMcofG1plPfPsO5hTdLGCyW9YjE\\\\\\\\\\\\\\\/xj5xMxctqvGt8EvELxUNtsm5z\\\\\\\\\\\\\\\/Eh\\\\\\\\\\\\\\\/BWH\\\\\\\\\\\\\\\/+FuGeNOcfiHtfuik+vWP566qhoQ9J+VYSOWhdZtgeP5mghZhrgW4drGWU2e4lvpk2u0y0RJa04BJCeJ5t6HnNlv8fl7HPm\\\\\\\\\\\\\\\/RkrAL8IpGivucCAKzyZdUHf6Z833LuENzWbYU46xVJO8PFlUhpF8QxOBQgiFkKttkamrb52sjqvmskmweggxUXs80JWUQL3ia33anw8wbbzS+75sBp1jr4lgdRXJOvFiIarDl5DHVl2MQI1B4UacuHmv14yYtmDatqagUrGi+EJP9NgJ4uhdT1aYvjw5\\\\\\\\\\\\\\\/jzySFVXetuuWPNTcjQreZsBs3H4p0fBY4BeA7UcBVSTWm37yJOlQSNdwp16i7SxaFgg592apZUNKlp+h9jxGac4l9On2sbRGCCQAq98uYXB8lAArgUs2J0+WTQrnfl\\\\\\\\\\\\\\\/5PBKbKLcNJX1HRXChzDGhUfZJvJl4nJ8RVmE5MhwQnFHi2rogWdHFmjLQMsS\\\\\\\\\\\\\\\/DN7G61zLffRoKJ2tS9VhIcA9TjgM\\\\\\\\\\\\\\\/2UKyQ6SPZxqRe7c0KuZoi2ek7ifA3dKWtx27r1LskW01+MkRFqwf9HboJygIOXfcppN4Nc30kh2YnTH6CpNvVms9dFR9PuaduZ6T+3Vwiz8gQdgk3lTa8RPqTvkEBWTEsOdIP4d8wO\\\\\\\\\\\\\\\/3FUy79vNzB6o0Tqtd3lHAdLviXYdOYx8Ylo1x5CWjZhXtOOnWHlOT4SNPkt2dfCG+C7V8Q1bGkl96CgqZHgQOvEvv+\\\\\\\\\\\\\\\/tTSi3p67V3WPIRMwoHsl7bdkQ9zUw7bkl4PbijAlYY5BO6MgN7L3rLNdObJ+qrv\\\\\\\\\\\\\\\/daR4hvz3rnYGw0ycc\\\\\\\\\\\\\\\/ZXtYwFMR0\\\\\\\\\\\\\\\/vvtotlzsiYAtf9t7VemZCdoRXpB2KpQenkM67mDrqNj6BxA6Ln\\\\\\\\\\\\\\\/AlOlr50p+DgIgRpxJC5REahT8QYARei7kgR45vHFoZuHr3TZcc5iNzzkk4PCPZx4\\\\\\\\\\\\\\\/rD5RlWnm7SIKRzJwjeyC0c7ueW0z1kJ9cIoDT6DOHdfzBUeTvi5dObigumYoSwV9sjOEZqczGz8bWv4QQE2kGzYw3AK5IFfvkdL9e7+7Mw9K\\\\\\\\\\\\\\\/e9qRz5m\\\\\\\\\\\\\\\/oLVPNV5kuUBFxqI2NwkmR+TXBG1I2V2IBGxu2M+WgMLn8ZXG6QMvuELAtJL4cE5qIvIhxphBQkPbqpeeXSUQiKQLbHKTdrtHljeSQmuzXWTlz6rPqQHe1bPf58+35sBEk2szc+rf0Rb5t6lucCXE4iAVErvLh1ULMA4t5qPoh3i8fSEchAS8TvhjDfU2Pnq\\\\\\\\\\\\\\\/fUp9iBlTCv4Yc3LaeQdXUN98u\\\\\\\\\\\\\\\/UaOpekg8fvgsHscoXXQm8g6JxDdkeg+Ql8WvQhbAE3Y7h4QcFMOzURKszgrokYs+9XeB6+pXLsAWlqqj\\\\\\\\\\\\\\\/DaB6b2HdhwLo6yNlWEaLUpANPW8A53bXjz3qYaYktMBPOgv1F8FbmLaiV0leF9S3roH6+a4bRPr97IehOG4V4\\\\\\\\\\\\\\\/sc5Y+Hl0p4pb88P4xeDIRPPnB4q0GERUc0TJWbhsNMyJATKDuB\\\\\\\\\\\\\\\/hVIp2m5HxKZ4CD6i26jlfhUo6vu9PXHH2c3hQwm32zyFbGsa2guJmQuUsW11LEVH6EsBBCF96P+MojvF+ig0A19aM+3US4Au9bAZd1OOiJrxOxYavRSd8u8yQtIRvLwg9hkQ3J18mPf+3SkZdZAUdWXON4ypv5VqdAGZoDlNhZqZ+oKG+bcSX3JZ47\\\\\\\\\\\\\\\/VaxcvgjsOLq\\\\\\\\\\\\\\\/t1V5dr3ZpmGuVuTgX3qJeiKOoPiaQlPJ4WWt1bDoIWtgJW7sukEGkgN9LzkOCetpBr\\\\\\\\\\\\\\\/ITMa3kCcNTSj\\\\\\\\\\\\\\\/V7HZMsANYMKqRdwcHPCk\\\\\\\\\\\\\\\/9qiffF1VauJdZmd\\\\\\\\\\\\\\\/vQgNwfi0hZWcOLxiIsAkMQ0q5LXaxkumk+SedbKpzMsg1FcV7fDl\\\\\\\\\\\\\\\/IvA1bqu09ULqJEP+IfjQj6WtZfJq1H1HuiNukV+wv7L2izy3qxBdrnayWlxNG72KuFVZfcr0crKldKzDgQMSnjFH3MvmcTRro=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022TIGl4\\\\\\\\\\\\\\\/u8x9seAKS750qI\\\\\\\\\\\\\\\/g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022034770db530fe333e6694991641e6e80c775341f6ec2187499b3726f12e44768\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A204.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A204.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0180\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0180\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0180\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}