{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ReGeWZZg9z44qasqAtUy610I43Hx49LJoo5Ty8eKa+0xRq5sA4PXReGuOqTcLyXpDhSSXJIPQfOizFY1gopECbM7dU+fF9JV4wdimVwaALBFZvx+FgrT52g0qTzHARaCrafvMvU3tYcV82w+PJksEFL52s09Q6fZhqyvTTlRAh0o4B7aK\\\\\\\\\\\\\\\/Xj5jPhNUn0yAJ9FjUTKL1ldV4tDzi+wFe7BA8q3HJsbzeim8ztUrswfMQaiHcGjdWw4H7hnnd9qQ7hxRUEqUekefQdznkQL6kjERk7717ANeoB1jPQ\\\\\\\\\\\\\\\/KTzXe6yjC2T94n6UjeaPcPfZhOVqX0TJeGeztSR9zTF52JwwJBF6g2NeSCm3FXB2ouUD0wwJNo3V+W8mF62dtHkUYMqXs\\\\\\\\\\\\\\\/0OBV4e+LzDDnmD30BT\\\\\\\\\\\\\\\/a\\\\\\\\\\\\\\\/iyHAVD1E8W70ZYNPqMksksgLcJjLITymBxcMvuvRpNpGTQyVxI\\\\\\\\\\\\\\\/6w5hJ8aYTOkEz\\\\\\\\\\\\\\\/sYvC\\\\\\\\\\\\\\\/g1SnQuckR0+wg7dUkCJupYQjdzgRjyFsTrZnZJc2hb\\\\\\\\\\\\\\\/DUlX6wAG705FLhC2y1Q3wkOjhObkFJW4JRU2CZmN+R2OABJbQ83JFcT4Py24Dx\\\\\\\\\\\\\\\/OlDwKSKUXk\\\\\\\\\\\\\\\/32fDolmIBYNB8f\\\\\\\\\\\\\\\/lKat+ydtFVzq4RLavyE7+RYNkKnijeo6LD37FY1TW7ye1dh3Z\\\\\\\\\\\\\\\/DmdFX558y\\\\\\\\\\\\\\\/OQYKqYKazz694AGiEssWsEuCYLSgPbtF4HyVThzPh+Ua7kSKmztUdC54DTBGLS\\\\\\\\\\\\\\\/6ejSePRdlT8kXniSUog2C90\\\\\\\\\\\\\\\/uzqyMgssqDwpPrMQUHaOXOflPwX6xMhZCRvq\\\\\\\\\\\\\\\/DSH5m+yYsXITgsYEoakGSFMpaOB3V6Ru7SSSeY17NO02PKiDuA3Cn8INw5ehQIp6hV2LbfA87Px+KJOA8K5pzL8cJVwcbLEZWZaulImxQ4V5sk7fIwrq3tZME9wTcYJa2ld4vhjo+lMpa5DM1ag71Zkb0blgv3xMBaVg\\\\\\\\\\\\\\\/+FGCthGnI2l2NjtndhQx4WloBNWJ3sgboKKnJHXHgm8B+4F+zklsF5YW\\\\\\\\\\\\\\\/FA5SsQE99IyHzwfK\\\\\\\\\\\\\\\/h8bJ9pkHfCySaTOEKVdgGOzNUOo0uKpEGYzET0aQtWDCVj9qtXoDkaJ7RwCw8KtUGgfpkF1kgOrst40dhoJtm2xf6PH+VcslCWrvbT0HF6L4PV79cK1F1\\\\\\\\\\\\\\\/SIP6vd4kXLcwdokx5fzbmvXnFqoRumCy+qoVoWVxGZ4P3noNvwYNpLgsgwYOpVvUlxvDVp6U6LEBGyfQS7Uu520tWgDd5edahlkMKD1XaHOCHqs3lq581Po2wIXPWYHWhp1yfvp1zHyhtK3hP+g5UGK4A271cfWwnGlBFjBX7Q648LBOkznTo0rwrX1Ks3g2FGfcy335WsjfRknLSa90OHNFY+4fQNUI\\\\\\\\\\\\\\\/aJbhwgu\\\\\\\\\\\\\\\/9IoKguZbtSqrXUfr3bLVhG62rxDeEG7pwPkCpn8\\\\\\\\\\\\\\\/RoYMoRQUr4wRS5qkAk45OCgUSLy+ZH5mgEhdd8rFcyiYfShQQAL2Nzk3bOtuTDrXGed2NDkaydy1H5jrlKuPZma9V5aU6Ia31oxRiPUQgF8HvwkFAPff7neOUWBBcAwUiNwMXk9JRteCMJ5VPKXlE7w8Pzc7G6qZM+vUDUUJh\\\\\\\\\\\\\\\/Um1TSy0VKEKvTBk6X+VTj6m1PLi7jtyQkmhO\\\\\\\\\\\\\\\/EMQwS00u6t3MX+5dPUV6Y7riyjr6jMCSeNkLXvqs2pwB4AKMgQsXG\\\\\\\\\\\\\\\/hh38B3AhEkBm6PKgBOsomA1AjfUbaB3xg1nHniS0ycOiBR+q+7QL5sRsCK9K\\\\\\\\\\\\\\\/OmyPknlBQcMMVnrM3C5AqJiNoyGIYwCAxU+JEBP2UrFB4L6yzA7KdJWLVVNOAs4W56YjHZR5oGta6E1nxEMnwkdmfDYCTKuAm+CoKlgyUTsM9D3srJvGwUtCsKA3Ht4rza3vK2kAjNeo889TOdDoOMGXhoMn7KmrRfC2UiRJ4QsoKD8VrURuaA\\\\\\\\\\\\\\\/GOqv\\\\\\\\\\\\\\\/spuKb56tC611soowPbCHGlN69FnesW6MXSuj4XMmWko6pofNXys6iM3Zch8N+Au5R3obRC8+VslOCFIXaLzENko+kiOqnCzT\\\\\\\\\\\\\\\/xJ+TODHODEPOVEV1+DTjTcv0VA1jWbvUlF8Gc\\\\\\\\\\\\\\\/3nZUWye4XMBqnc\\\\\\\\\\\\\\\/+kq6JKnnlGZiO1u\\\\\\\\\\\\\\\/lL0zYQx7w\\\\\\\\\\\\\\\/FHoOMAtuD2kSUh7ZLtyImyiUrik3SOMiIpWcoZwJNHUGgZM6x+nUvHws7n6Ksr3OLnTSy92mp0qHg4JTtyhcetk\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/WKOPmm8pU184pucb1cADhnejrWr9gr+iSqWn8iSEHtePJKzH9I9WtxVsod+cl34k6ZrkzHjh3tYlFCqWrScFFAD6IBbRRJFQ6GD8e75KVuV6lEboLl55V9LxF14wHyoTEkWHrbsKgt6L0r5qAu0277gch2kbHov3FDZ4HdEXZLvxVTvXIuXx9pu0\\\\\\\\\\\\\\\/eeh0WTGaTjMOL3v1hfNxlmrKzfj\\\\\\\\\\\\\\\/Sdw8bOeWm6LsmCWSE5fVkjVj1TPkIuG8jrpWgRetUMNO\\\\\\\\\\\\\\\/2B3KvH18\\\\\\\\\\\\\\\/ydoI1iJbWYGzR7yDoDrB26kuVaJdHPwX0ed8enNTjNpdI25xb7lnVSEbXZzaGgDCzJn\\\\\\\\\\\\\\\/zUCbHM8ssBf9HhACGU6inem5G0F0pgzRlX2rGJ8DG0uFVG5YXVEn2awm0I6hzgEeNFnmU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022YP8Ye9Sp8shBLAnJ0BELuQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223b45dd49593a66a8a5e0029f9ab28981b443f27758aca87fd2dfb77f6c619ed0\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A731.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A731.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0639\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0639\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0639\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}