{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022cuKil4y0B1oZkEGnPnVK1bgxtReuteNnnAD+CYjEnXxNtyBGBtl2h9nGyNSJW0xnhw6lvZBcczhar\\\\\\\\\\\\\\\/2jYcgnSk8p+vSePNnxzVueoymG1lcTfFPPyVkb+Ax6vdNXi0Eos6QYTDjhBpqjNOgAEJWVvD\\\\\\\\\\\\\\\/s2Cp4zNN0il0kqKk5C0x7+J29b0R7FmtT0h7KETkeT6Q97fn46q8CcWdgJj48L9yIbLy\\\\\\\\\\\\\\\/N2a5duRYopJf4aCCUCUr69QuqItCsVv3nnu8UsINN4n+2QBBBfdzDqSas75RtkbBhNIMsfEUAfEEZJIpP6aSX1wyFClFveQq\\\\\\\\\\\\\\\/Sf4ChV4nBIXC7t7fwYUHlXzp8SczYv4Ahyz5kPjMu0DokkQVGVvfOuJYJBOxGHkdfFkTtZFz5zLB8udTQFkomh0GCzHPfi3MJiIrV+GXBZkX2KpNa3n6cDUPFH30\\\\\\\\\\\\\\\/Vn2ZrR68Wnue+OrMsKqw3unN6Gf8t1pJC3oRIbUYtGoYYEVQz0hjB9g9LBqr5B0w+j95+R6xRzPXIVF7tIvYJSO9B7XGf\\\\\\\\\\\\\\\/qH8YTpZt45VrLMVQMw4mxW9Jq64cuNTB69A8xGcetAc0OPhedSOdzeTX5mn4Btku4Pjwg4Hf2IvgzYgWw4mz60TiOH5cSCETKL4C\\\\\\\\\\\\\\\/slAYK5GG+57hoX4z57fy00gGzJD8YMt1FQG+eCSj2ddAHUrzy3r\\\\\\\\\\\\\\\/iRzmBPQlSREyUxRVMCQTXzUvYd7WAnmok\\\\\\\\\\\\\\\/qUeLLifwggIsKsJ2IommB1NROzDbXkdCBXt\\\\\\\\\\\\\\\/nTLEiiVKeaO5kOHybf\\\\\\\\\\\\\\\/RoCBT4NjMGSvh9fe\\\\\\\\\\\\\\\/CAO+uCe1gE+vWqkwIR5lnOeWoWUF29oQtZCUrw4\\\\\\\\\\\\\\\/ysZ5B1A2vCqIxBfUEsPRimlkkxOwrozDvLDZK2gjeJ1YU3+kWXnVP0hq80GuwGMGnE39hFKdizAIX4+GmEI5MFHahvaVxw9azB+npcW1+b4dRFz8uer2dCGtwVmf\\\\\\\\\\\\\\\/dW9AlTBGB7eD1qreehh0CTHNalHUScUG0X8ZhfifG8SaNFkvMqZuH+XX+Sh1EtlfHeLQc+qyVXi2hj6nN1vBDjBuwA3upjmD10e3SUAoHehU32c7FCyJLpCQil7cUeXEJx9PIs6IB+g4RZjLUEhmKmvQc+DNMtKa6lWQDB7k1BbIb35LPpPgM+PO10uneJCheI4cc4z2m8BsI0GOwnC1rsTDRAlB7AHnVpe3+ErdHVoPnuh6v4GPIWttrX\\\\\\\\\\\\\\\/3Nj3nabdSBD7A2xhMEb0BwD9fyYKkgy2iUzZrs27vuY\\\\\\\\\\\\\\\/XAu2IYB6VklmfAfxFuJeAvXYYjT2r+3uDHIwIrGzDqN7ApWxQLg+v9kQi1i1\\\\\\\\\\\\\\\/l73OrPfbS6xfl+IkiEDcGKRw0GRI63d+hzvWKH3RdqKYs9spyq+c6b9Vv06\\\\\\\\\\\\\\\/Ncz4oi\\\\\\\\\\\\\\\/Nons5m5fYckZvRpwWM8rqZIdBaRQSqTZNJA7Jqg8dZM8ivTBIKdLr6s123QJ6Rbyhex4aeltCW7hB5vG3wa6nWVpeyqRq79Si2gVf21QmW6XRYyzO6Cpw0GfAQo1u60ts0BucaazQq\\\\\\\\\\\\\\\/yZf4uMlchSLnrkURUTleY+DwMv0aP35gBDEgEYvTEAffLw+P+0RnMICaeYpumdCepaactxNB6VvY8xr1x4YYsxF65PthgoCni0yJUAdvU\\\\\\\\\\\\\\\/SSChE9AWrT4x8RSaMx9JJTbCucLDaNYx6Ee915N6MBJMPwjni\\\\\\\\\\\\\\\/v9GK66eJyep2uSP62xEyGQ4y4ylnCeGR8EpFIO6MbGBtwlEMe33uLsKHQ\\\\\\\\\\\\\\\/qWitcUZMFr\\\\\\\\\\\\\\\/ZPPgLa5hAO55147pavxOir9rlXgWKCAo5A2Xsssl9YCfIa8ekYSH8TpLa69JLF\\\\\\\\\\\\\\\/d9rMxGbK8u+j+5xVyaTyeFgQybEUibIlgp3OKHQPKUqh2k27NpeqnbFQmeGUTXz7CLYP2MIAT2TVvgVMQeWatP4z3IEiDcmAVY1beXLTuzDI3ciYo3ZhI+ZJroGcDnctSaDEFZVAkee0ftlXZ\\\\\\\\\\\\\\\/Vmu+IRZ1V0WNiQ4Ht3gmbV8oTpUHYKMaM6bBd3lE92Oi37CaZXF8t1ikTkLcewvLMjGTl8GMVjdiaCABv16i4wtB0pTPLOCELL+emuSxc6mtL++bvcJfG9u5NgAjZMCrBsaSqrGTsPqghSZ2RZRy1Z0dEXQ62h9Cd\\\\\\\\\\\\\\\/pFBy9rlN\\\\\\\\\\\\\\\/ozP\\\\\\\\\\\\\\\/7bxfL8Bd4jm94eOzR4Ulr0JYhRGlDgZEe7iwm0E4rzDoS0f\\\\\\\\\\\\\\\/RP5C5Irlp37I2XEj12BThJBQzjJD22gJOcSL2lbH+2uoUW8TtQM3DcgznGu1lM8MZQXZ0UQHFDHi8YcrHxT\\\\\\\\\\\\\\\/TOTNzukwiuH1\\\\\\\\\\\\\\\/OtLU+qx7zYahPJNZN85MwQ1zBzd9Aj62e\\\\\\\\\\\\\\\/h9IIvGV7LiBA+Mft6hpt7felvUL8jkSxJg8UDXdA0iXaA1Wgo9sRW6DwJ7CAyUnhuEfAGKrmXm4fKJ8t9wu7vJCif4CNuMxiRLxc84GJ54d0OKOzCWRSsnOwtt\\\\\\\\\\\\\\\/igj13qhQv\\\\\\\\\\\\\\\/ae\\\\\\\\\\\\\\\/x9\\\\\\\\\\\\\\\/Y7x\\\\\\\\\\\\\\\/ri1p1LK1E1YaBMgU\\\\\\\\\\\\\\\/NfOl3iE5xH8y4cgnnDn61waNR\\\\\\\\\\\\\\\/uiATDcvT69\\\\\\\\\\\\\\\/04bJ6LNQ2QFbWw1bKq3mToRHXTwXh9+RwVTerIXag3oiM0Nb+KnFxaXdd5WNA2w59gVyNaUMvcITUqE8mwjaWSR9QoTd80Xs=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Y1cR639SqiipTODmZ0bOwA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d353f741d742506b81c908e012cd86f816c80da5372a659945ba67f4119cc1d7\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A74.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A74.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0064\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0064\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0064\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}