{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022cFOJq2QEJzvhEqSYO9f9f3arLjiYyu\\\\\\\\\\\\\\\/x2+2MNucbdLy\\\\\\\\\\\\\\\/W4Of2m9yT5UTvmwzoOqx7pfGxU1QKyGMan3RGf7hTeTnm\\\\\\\\\\\\\\\/sEK4bVRLLRiHndMg1fpwUk6udBOIwJC8CchimNdngp0SitsrE7WtAUX7R08rHmjLSsZaVihC4tlXcy395CzyaTEakflFSvhzcH\\\\\\\\\\\\\\\/ZqTnQEz0bLUvFnZAPFzMkmpK6a6yhpLmq0Pu9M3g2vTv4VGIIje+7qgm5yWGjP9o134A6ESJOdvxK0PE3uiBj\\\\\\\\\\\\\\\/fNxe70PtRmkgWsFGoJzRmly9dREZqqy4eKFPtW7k194jA1vDZKoiCjPIeecQjLAjtspBQuIfUKE7LzO5x1GcsNWQzXEZSKJZJOIZFqYcBWZUBYUGThd2M+qFuah\\\\\\\\\\\\\\\/4Smk5+pOOXBgLafAk7Y0H65ykaTE0Sy\\\\\\\\\\\\\\\/SWH7ScuA62R2p\\\\\\\\\\\\\\\/h7sVmpmt+sAOxHapyKRfZdVppMFF3CiV6Qvmq9oCnGdcNr5KU01nzbZ5aGbsLJb5L7S0tzlOPpYKotmfSB4FuYt3MiIKZjQBtGWS3iYs3k1XEiSev1IlfjJ\\\\\\\\\\\\\\\/aIYrIrrkT1A\\\\\\\\\\\\\\\/wxE4P34saffz923UH+P7wVHgc6kHUqfACJe1ozg95LGfORLpqbuebWhXeZQhRJ4DV7NpsKiIVOOkIxbhIueHeqbdHd7pIcRfGN0yyDYKXfZGJtgETZXglCwOxawUiehv\\\\\\\\\\\\\\\/0gVXxsQ562VCE244TUhc\\\\\\\\\\\\\\\/+IRsNANmsLgNU1C0JUJsGGafKMnZWdXeGuEo5vcf9WPYFNVwBnmi\\\\\\\\\\\\\\\/oJcTwGFQ3qXMJsXM81RvhRhAdT+4Q3E20XZJuO0NbaP0na5XdXGMYuhUSLMpiZJOQbRWWrNqE4ubxIljlMiNOhDBt+QbSWflPRzgI78FiWsjSR2Vht4JDOcwaaO8V+DXwa0qmdonlcwhuKlhWC85XCHEaYeikqsI0kILTyIFTESSmq74tc7QrC9T6E5Vz\\\\\\\\\\\\\\\/CcWxf5HIovWNcsLcxXkMTefZ+RY6DcKeFWM2x3YfTW6MtDHlSbrBDZ\\\\\\\\\\\\\\\/jH41\\\\\\\\\\\\\\\/HQvd2ntaQTFoZedo7WtWtcFxKJCMI7hopy8fe2t+rKA4BtGSArmSzHHWd8Sj06LdZDmtoBDtrK0Y1NI0muN25u691VQ0AK0PHOXjCHrLxnEs4ImrJE+J7msjgEMno\\\\\\\\\\\\\\\/Io28zk8ZGOWICqUcj6B1EZdT3wtFXkQFxn7AI4vpiKcsAbh+To29PFHADIPOPloxdN5PrI0b2HDUfshTW5ziWPvBawyeeB9+jba1QHU2aLatNs8TzcXrFZbtoyO89qF85C8nKvSSyPFw7K7b\\\\\\\\\\\\\\\/r5RihhL1fwJE3FGeDyoqMvBEFjSDESpkFBFiDCkjAHvCsc+YwPls7oJD1yXPk8UCejtv5gMBvvd9IHsjeCPrBNfaq5LXFqChYJKPes\\\\\\\\\\\\\\\/mJ8Lnj1qXjAtceG8D1ISGINghijaF\\\\\\\\\\\\\\\/7T\\\\\\\\\\\\\\\/Mk1s\\\\\\\\\\\\\\\/InCh5Ck0nTA+CQ4WOAUTxmFzRmgy7k+IIaPxAgN8iJpZuGjP0TQTxWvwoNBCOJk2dlBQ+PQnXc6UABXo4JV\\\\\\\\\\\\\\\/m+tbnmWACniOGDZkyEXCV7geK17\\\\\\\\\\\\\\\/th+m0NTE92W+BMMpfj\\\\\\\\\\\\\\\/ndBXOvwZQKj7VFzGSMbMTKBpaAcmXTp0iZaemV5Vg+2AO+QkapaWljo7XMGy6w0CyEQ\\\\\\\\\\\\\\\/zPtSkL69RBOCR3haEdDNVR5DEKiDUX0mkbOM41BqxP8fS52TuXiat8UD0quuIfY36aHoy7AumOlywYPjg6tAh5xycbNzBQFL+q1kk\\\\\\\\\\\\\\\/1kcXWHo30QRJ1PaMw82d4lOYSDdIbTn+w+b2vWzGdQwIXDQjJAozeguEaqwAw2dPwaGhcf69fFcKkYYEAOsj7ieRkg4aLyg+PGv9Ed9SDpA3lHVxz1x9SST21EzH9F6BCIHjRLKairnM+g5Y\\\\\\\\\\\\\\\/NElBosDRwhLIcQygNcclo3G+qsSyi1giddog5I19skGeomloj3gEe4spZqW2tyKvU8q97taJ3wxjSUcNfgOF1zARiDH9uLEwMVmveg4ZAMU78IQ5kfzC1iMJQ4k0UtaLiFlnLfNrbXtL00Oq+QYLVPgiEmAi0kPuXdKUCVQiUt7IRESsLDlSpQSGmqRzJm4gdjXCCfdr8KgPN2qcxURA2cZl+CTz8arZFIpNHhxSWBpyu6NSYOZtqQ9RCesqEq+pyBXSwt4hOooNjp90B3QP\\\\\\\\\\\\\\\/R7yM1rDtAqnaWVDAkI\\\\\\\\\\\\\\\/TBYUi2gMOFabSM90XrNadU4GZSpJHhza4xjflpQgGIup5jB7Mn6Pt2SBSF5tOvHtfDkGxx59ojTxEEvOf9cdR3S0dtgGC4M7GyjNalUgNT7lX1\\\\\\\\\\\\\\\/rR8WTfNCs1cDYWV1ixGUYCPluq1xkpSQ07H090pWoF44DNeX5nwY\\\\\\\\\\\\\\\/FebgswIrMWkwOB25IsIjCijZTsaOQ13FBy9ic2BV3VoGoITDsGkZnzRn2ryDW+MdeYz\\\\\\\\\\\\\\\/SoIgfkx1cTOcSOtwHrExEWdAeXw3uWJaJNxWszjxxF2jfs2ZXGUejUfoDmydEBEqMm3GRIcoZlSeZvmQExLpLc9rd5ey06p6gDUmTu3BEGE558HJeuSjxAjDx2Hs7MqwizXzx+aEUFyDdfeYjSoOWFnps\\\\\\\\\\\\\\\/HxHFjGdhP3BBMrOZ8JKWo1PpHqEQSRJYs=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022iyZ4QsPtaVJ69P0u2mLTxA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00228ea3ad7b8670388f84b239c6723edd951c38ac8146241ea9226415fc0750c8fd\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1572.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1572.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1414\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1414\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1414\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}