{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022Gx9JoZNUZY7LROsrOlc0HE6q1tXR182UmJRPyRsQnJnp6PVkn\\\\\\\\\\\\\\\/fwFDepkVFOuvLfJ\\\\\\\\\\\\\\\/EUzKxCPIZdHZoZ9uDQNatoYt3bDn0YgIxTOqyv7U5\\\\\\\\\\\\\\\/HLFqNYYEG3jTLQ9lEap0nKb\\\\\\\\\\\\\\\/LslbNIjW3fM6rtLVqhJm0UZQGUFU6KODkJIcpgMBUX0oKEQMiVVZ1scvpZyP1Nr02qcui5HOiU3pkkVkl54N0cumE5M6zVvhwN\\\\\\\\\\\\\\\/zSXp9gjrAJbCHI9xNCPRSNErtxEIbA5Vcs9ZfDfvXLLSVKR6U4P+a9jfvu1dmvB+CKY5r0+S1MKgm1jQoAzAxWbnT3H1SrsV8lXWa\\\\\\\\\\\\\\\/Llx9b1g6gvVXg7tYH2zVpffTehjPEUIjOpajiSNcjbCv8bwsLf07NAM1lTs3bAA4tDkiwZgfwjWOjRKZ3CybSmYFkTmYy5w1+L9I7FRbZkMIniAvl85ywW3AiWOcrN\\\\\\\\\\\\\\\/pLDleybDtHoFIJ2qnAxmqInmHftjym0stgf5EQhNY9ks3H6kJB\\\\\\\\\\\\\\\/or3Q7DaBeHURrhM165MWSVDRSSIWi4jyhJCTzTFpjy6go6hD7AFnMptBTFYuafKsqwDvTg6V5ms5uqCDcdxn2RyDey2df\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/Rhh2ZNT2LNa96raDmqH1A7v8\\\\\\\\\\\\\\\/E4f2Lj\\\\\\\\\\\\\\\/lQ5ckJNvduwtUXZ7g4k0Y1Y59Ylz0cRM6VW3tLpT\\\\\\\\\\\\\\\/NheTt7l1dNo\\\\\\\\\\\\\\\/5R2KNLMR+CrUgIH\\\\\\\\\\\\\\\/CICcXJ58CWXo3AWjetT+aYK6j4vplHM0di54EndUSdd0FYCT03bSO6e2XDm71X1m5YWnJCCuf6DyZ6TgrD4LqeFjRx8A5WjsNdkor0H4thQl3KYH5VunxPPJ18mzX6Ilqq3VPwJTR18o4FWSPAkkVQhGDShLHwXDjrvqwlfmBKOq9JdNyp\\\\\\\\\\\\\\\/jGVpOrmsvJrJrKcVCywFrhW\\\\\\\\\\\\\\\/zDkF5+vc6wWe0XtO2+QPQ6IYBkVEXkldwTc5MzkPEnarx\\\\\\\\\\\\\\\/SMImxh1Im+2fy8i1JOgTOa+4ECbJCSg03hIiaANCMnCsq2+Ew+d6FhwamlaN1\\\\\\\\\\\\\\\/u1Y8VjWhWcUu9NL6fSE6OCHTtk3R\\\\\\\\\\\\\\\/TYHMa4sWawBvc1gDoIGJbhrX3EV0ZFUXVb\\\\\\\\\\\\\\\/ymXU1\\\\\\\\\\\\\\\/kky7QVjkLBUgGhoK0oH+lKw\\\\\\\\\\\\\\\/yrIJxmUYOCvoti3qWAOyhBaH7Grp6MRvbrNplO1w74uPJVrvWly3mDGWp1zsoDUXUmYxngrsYpNGNlk\\\\\\\\\\\\\\\/s8IFeJ7QvTUj1+t9E\\\\\\\\\\\\\\\/EBxEnTqzO7x+XeAoEYVDAS+kfUTJnzLjQuafCAkFblu2Ql61nqAmAnChYtxT5as0teCJ1i9EWilS0RQm228jCKQSvb3zI63kRJzCyRA1VaXYEpWxx20TSENEGRek5pfq30WwIZn89n3aKtiY05QCX5Q2OxiK5ANiN\\\\\\\\\\\\\\\/rAX9kOl5EidyC5aoEhjPQmp8iSEbK4hNI3ypyJ9Yr3yoirWJZ6pqBk7HzeP0yH3Nj+KQwkD4hAXPr72LKTLzbXbpLL3u\\\\\\\\\\\\\\\/zKKM9ZiajlMQUSfipRRDxCfsQNHWrluOF5vH\\\\\\\\\\\\\\\/KPz2zbUvTY0xpjNEPPxpq8Cl317Q0WIm+irRkG4xjc3+bxqVft0jhP6QZPUR80ea+RHR8iKT568nGVYhFdgz+laxCJ+gVTmTFbn2MlIn9ClT+wCb1cm0HCQILcORbxlaG+OJvAY4ahqrfsJWzZVpUwrJWzW\\\\\\\\\\\\\\\/0QH7+4MoO+iVRdWsZ93beQ+xsP\\\\\\\\\\\\\\\/OpjnfixRvOYQ26zBGun6\\\\\\\\\\\\\\\/7sVR6pjZFeV4rdvPrAs3cOPlKIs\\\\\\\\\\\\\\\/YTkfxvrMiMwd6OXYeZQx6ffKryMevUOxgEP9uOPVQePNTMGrX0yfedANU1QvJVAA0TUjbjw+ZEfDwIaeHeBSCAhqwaqNU\\\\\\\\\\\\\\\/3ZFhY9kS1xtBPnnBfnD95Z59CPi1Up1nTRY8ySXiBhOTJzE8TgVZ922JE5KacH\\\\\\\\\\\\\\\/WYDjahleoT78pk10SFFVKXy0bdP1H94I16boDmgTHbhDU3IUFJrCG3pGaDZqsdm+IqL6qUWhD2WBixEmTSE+dmK6dM9nOtB4yTzkdbuiOnTeeFfjcl738F\\\\\\\\\\\\\\\/1+HpLKVJimyM7+WZuWCCn\\\\\\\\\\\\\\\/WnOEGGCsJdiSQ2P+Vs+Nle7U5NnAjgSVCpKQdA6N4txuHRBQM8tfocMu6Hnm4pLHVJT9g8uULJtJpQsweAkSkIW\\\\\\\\\\\\\\\/fh91dSVGgdpGZw2EISOJljw6q9jM+F2a9tO4mJ7UCUlhPfIKjV9By9W4RI56pszKHY6WJSWNiBrla0luNxNtCc2KEL91jgSpL7EtHLok7orYYZLxxy4Rtx9l6nlaBZ67Tf+vHT3Z4YDWdL9tHMC9ETrAeGispyeVsgMJ0pIb0AZe\\\\\\\\\\\\\\\/kwaXYBEsPVPdD8gfl9uVMJDxsS\\\\\\\\\\\\\\\/+AI4zUJcPCgaU7pj7P25MsiAvv8qj4W+Py12JcexHkbL6dTUO7V2DnZftxfeo88\\\\\\\\\\\\\\\/bVe\\\\\\\\\\\\\\\/aDoiTD\\\\\\\\\\\\\\\/GZU+BJ\\\\\\\\\\\\\\\/9rASuSKw5G7zh1coxCDxkow9M61cCcgxwj7Eof7RTBiUqONIhbyb+3945YDzrHd7uAho6+EqiWGyiW5Z2UIXTO37H+AJDFw8xaASVvqhetxFsWzhpktR4ggIJKvu1S9kHo0v1ahkhPUFLSBwg0VnvZMG6AUxV31AvBPkBjuhRRPphOXuEk8BhS1a+08Mv+eCrxQw85txM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022qLEp9AknmzIpkUBLO6oHtw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022856e1dc278095acbeef08275cdd12bb99892b29218bf371aa8fd141c09811e1d\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1674.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1674.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1509\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1509\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1509\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}