{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022t2aSCC30WPWry5Tn8VDuLR\\\\\\\\\\\\\\\/QoUWZ1CSaMfyrJZavtZbfS6m\\\\\\\\\\\\\\\/hr6MjldUpb+lgTRr69Tt8QkBO9NnPRISd0WmCK\\\\\\\\\\\\\\\/H8P7O4CYm8bAht04asjUYNAU9KN1JyVpzmNVFdxUPGeeXcvGPPlYRV2pzvjqOT28wGxtbSj49Iuas0GyeKVAc+5pccwymHomDXy\\\\\\\\\\\\\\\/drt5irbVnygYmCK5dN9nIJir+ibbEIl3KVgW2FXCLloP8b5xUz1WezpFIaKmJ\\\\\\\\\\\\\\\/MKqibPuyhirp\\\\\\\\\\\\\\\/Expr1flCebgcqu0FRUrqQjULGxkPAutK55ZNVv54LxUpIfQeBSh9vUnrvH\\\\\\\\\\\\\\\/Ot\\\\\\\\\\\\\\\/yA9jGXeyvizcyVlu+KoqnWSF2T3vxTWQ6iLdTmIk8H+dXrXb5M3k6RhJw4nsMEK4Bz+0hR35MszFnOCrp8k1BrxR+kzGPQ1LVwVvxDMnnyuj2ldDjiRVv\\\\\\\\\\\\\\\/3518++0AgTfAfVP+aPUa5lIgPU7H1pwAHGC+4WeDplMTwvuSsztvUmLBF+Y4XGWo6tAZLsIY+C5Qtt7WsMvtFEzKPkTxNC6nz93LdXLKuX4NBW0k8+cTh6Ekwt6ARJEXDz7GcLYIDH6n8ekZTEDBbpbqGYQq2PUNEPhYdHh6uiz+Z5j8HBQ2M4UbISxz1V1xisYTOWcLN0Jq7iF7H6pb+pUH6s8vxdJxCnSgUO3VfE02bxPlpt+TxojRqmX6wheonjIt+wDbx8BHKvcJFWASIIZXDBtzPJq64ClM6Rl0B2+Bbaliiqj93OjiejNfQX\\\\\\\\\\\\\\\/PkEHxmS90qqtOWWhASAz7GNHKfyL4nb\\\\\\\\\\\\\\\/Nc7F27BzOvxszFgzTNjECNoudft0zlQrWxA5sWQTwQHCHlqoErXX3wTLnoF7vvVGmARiIbK6QaNlKkIzDgIXOS1ul6cSF0qGhaMHTkqiHF75uVrDkKyZFme68anaY1nkx9rg8nooxcPYGPdW6Ze9ECyWOKdBjPE5QysgD9D9Nobxbg8lm+ZBerhrwYFTlx2Tpor83RXzgoFcZRZAW6L\\\\\\\\\\\\\\\/aUxaJXPo9YBx7LAavTgLdKt5zqvGTCiPcj76jBudV\\\\\\\\\\\\\\\/up35SR02wspgRCqPOym8pq\\\\\\\\\\\\\\\/1aYAaXacL91o9Ggv6sVEMfzOoHdaBX\\\\\\\\\\\\\\\/9qJb0Lu5P2tJ6yOZU6whGI+NKVkd3sBeL167bk2Pivfm1Keo9FIbU5gHH\\\\\\\\\\\\\\\/+BzP5fxfJ+ip2X\\\\\\\\\\\\\\\/knpVCR32A+hWDHRQEGDoIpmKrtDaIxHwuZpQ3tSYqoPLbJlEo\\\\\\\\\\\\\\\/v36ZmUTRToIfU3bTYTB0Iqxjnvz9ed7j05h9oiyuZ+k2znTnqx7nKSntVgkpHLzuXVD\\\\\\\\\\\\\\\/jcDifoVJ8KruB\\\\\\\\\\\\\\\/0nZYTl2w+TpWX1EmNys7slTkiVMYlsDUpFENo7g9KH8iZCIWOz8npeQqsZi98\\\\\\\\\\\\\\\/ZeAAUvSLIoYZKiFikaf9h0V+1AcdYbhYw+OYW057OkpOqI5ZcMGWhIxtfXJBCkRpK4sobF+T7IWgTra5OivVwyWhmc2MoaQbRsxSHCf81eggXAU8zVmsbgqw0W48xPy0WsAIYKGiUjKOSr6782DXpJOX1qvJ24UJXOn4hcid4pmB8RkQL9IPT6h65Hqu3biNmpz33WlIzDww4WX0C840YGAm9vQI3ro2ekGUnp7X3p85cMPThXSo1U\\\\\\\\\\\\\\\/og5OlJbxuM6IRQV+jS7lRTIv0fggxLYCRYb4XqsQF+kvpSpv+040KZniDIaYeIiY2UwC7FHexNBVTTdp0xrPDrhXjHY98yCdOVcANKfvDWUkW9Tkc2M0TGS6VKCSJqRYqqVhlIwa0Gad2ExPfrygVHRuuFu9HlSPzzL9Wqo9bVJlNMNuhuEtJ+5U9qHxdlgSJO0oRwo2vHW9GS57R5Zj5vi6\\\\\\\\\\\\\\\/pf12sCYCFyautwjkeXZpAncZWy4wpQAq\\\\\\\\\\\\\\\/IxTLXL36RuDLKPovgv7HrKXBGp+1JvPFc\\\\\\\\\\\\\\\/y2nUKpBuPyG1TffQGcaHo1xUEUIQIDLSvRZe1lfG3E3UxVIoh6mpVnUOS1m\\\\\\\\\\\\\\\/uJIjYrNeqwD77V0Q2OMtFNgznxfbV4OLWgsPu1RhVGmY3ODBtd36rpA4hWUko4+P89wQsQxWo\\\\\\\\\\\\\\\/iD9yyVJ1d3aicRrVSjY40D6VR66x+k\\\\\\\\\\\\\\\/NPqTrTTXz8+Ta5xjp3s\\\\\\\\\\\\\\\/9YuYzam8gF+9IIe+Kl2lwuC+j76qVGplC9pTrxzwE3b8ana7je8GuHNq4FPEqVb+YYSBLmPMUxs0U6q20fij02kITnsm32lqt\\\\\\\\\\\\\\\/EBLIcELJfK1i4HxxaajYZavqRhxbGtgs7Zd17iN26Txznd95xeaS+fFh\\\\\\\\\\\\\\\/oG+ZxmjwIJUlbHWYN494Kp2Y0w267PznvmlXdU5ihAofoFv7cGnwxemmBQKwSeelsedfinXCi1v9yQzucM7bw3UmkW3p7AN4GnbXVgxFsx15u\\\\\\\\\\\\\\\/vDMUrjDW29ZV7ITO9urHD9glV\\\\\\\\\\\\\\\/yquHWK2zR6r2SYTzCcJukN32Y0JOizLpWI6Uyy9PESgaC1ml0Ys+RQkj\\\\\\\\\\\\\\\/1ntO4QI53T9fb1p4L5am42u\\\\\\\\\\\\\\\/CvuRB\\\\\\\\\\\\\\\/loa+rKIw8wiieIekXLJel6MM0KiV2SkdAixH3UQ0ysCHlk7sjgN+7l6YECuvGxbpOWNFeJ4OnAb+ekv2UvfF8lryxynj1ZE7UdgZIZiBWD+LWNJBwEGeI025rY6LVoxlT5CfEC4UMj10Y=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022SEyffmw6G0SgbBzODa7R9A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002296952b0ffbc35c37bba185a5bbb50412bdacf46acc385fc859d887f3ec5b21e5\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A437.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A437.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0389\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0389\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0389\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}