{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u002252eOxz0F47CxC098DVWiXcqjRN3hpsOU\\\\\\\\\\\\\\\/ozvvJNQ3Usxt4I942CqsI\\\\\\\\\\\\\\\/mkTPcL02Ju2qt5\\\\\\\\\\\\\\\/UE5JGypqL2CeQwafBPePi4EXOd\\\\\\\\\\\\\\\/uqAFUBsoK+bM5Vwr0D3ZekUp5x6qcYZnfTm75\\\\\\\\\\\\\\\/IVQeXVcXtLxWvZ7g63aU9BmXZx1KLrud9RxpOKpO\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/KqhojXzmoESriuh\\\\\\\\\\\\\\\/O5aqIIxeS3NMYxbRTjUMeCB39qtDu2uMBEMAOMLLLSZ4xKsq0otJqkPnVDYGKGCUefJquZhQ\\\\\\\\\\\\\\\/5hi14gkJtl96WuU0SMJweTV2THAyd1UI89uNXorjbxJei6uJbad3EqVfCUoAounptfjU4YTIK5DwfDnP3SKLDIwj9aIbKjQgkyrJ+YYtw8gKbW64ubcxDcoPZDxVFiUTkglqcND0y2vqqF2vDdgzHx+UTIKMLrMrfSryADFGbT6Z2MULVQPGlY8U8rqJPJ+ad5\\\\\\\\\\\\\\\/wCxgL9FfekItGoPD5M7DhHz4kCgbJ719l1ooKTl4zDAq9PifZf1vjeBAfAOVxfQYescJkhd8U3QgAerpbVUtjEN6tsJz+wSOse0YYtJwwzzzuUwnKAICXVjxr9BI\\\\\\\\\\\\\\\/tZ+6zWQWpidw8Zrzz3MtEop7usiaIrNZnUDeTR2VyZNebSDufP7ltNdyghLlrzTJaZqI1vKFpsVqDlda4dayfTKPLih3ziRcZbEGOABRb+TFQnjjq0LVjLL6bjM3RW0CqsEbECg8Th8ZcYEKeu1CX0rGBoM0hj+9Og0suofX1rsro+3AMyzjN6vsJ9jgRTS7CmjQekwokllD\\\\\\\\\\\\\\\/Zdi+UY2USyaEuv\\\\\\\\\\\\\\\/pRwtuPc+5I1MLiH29f23k39FXw24MMAxxB\\\\\\\\\\\\\\\/gJCO+3i0Ut2mv\\\\\\\\\\\\\\\/8K5jUYY1vdujEWqQjP2wtJOwGirfaQEAT5SUP4g3VUN7Qoi1iXUgH\\\\\\\\\\\\\\\/L+m\\\\\\\\\\\\\\\/+CpaAL+WlvNZkhngOxlnfc8g5jmV+beYIYYFXAu9ML+Q6cd4c1GeeW97jhHHUGBR1cVe\\\\\\\\\\\\\\\/p40OwBgr3pRUuzgg6XkXnuJpcqCFXbxAiOTO8VUkwUK0rDJGuFujjgKZGCFFxNTzuA7re1kQV+Dn\\\\\\\\\\\\\\\/MTzxQWnjwYttWYTK+XsmWkLLERB8E499AmGrnOY3ubfY5ipTRAjeIaxSkCk8ZKxhLCxzqPMIhifAx1dmSass6R\\\\\\\\\\\\\\\/aZ7yC0Rg05vG5Ss1u2CliMcDvnW4Hm\\\\\\\\\\\\\\\/imGV9WaLRbZHDaKa2yFgwweNFt33oaPlKOeDvHQ3e2aAcsft9Sn28KuKznRtWa6qs1O1wRqFappg6Jpv2Vammp8E8lwZ7Uggt6620HWo1d9xmmTeFedChJ27OTi2aQCnKjecLofOB1W1PCftPTKlGz\\\\\\\\\\\\\\\/aXmpx0twyRyGUNF2laJX8kAx6QTO0ysP3FCKw6mVDY905fNqWURBCQzgJDXRBpnttf7hhVIt1LKQGs52D3RDfJbQN5irCZuFLlWfM7YV92p5l0pdbmV7ALbsuR6AcjPNBRGak2dnStvlyL7QRi2t0WTItYpWqIQBBqc5vVn94HGQkzZocdotodYwf39DSVZJsgTOhJQvmd2jXHHin2H9xuXaRdvpVh6atmx3RHlxL5kKUGDOK2jyCdWweAIvQX4MwNcEnQ9Fp6DbmADEM\\\\\\\\\\\\\\\/V8Z3uue9mPzgQVD3O+rrvu682IxCO3y736zfiWKEST689ncJNWPFTICxzIUCu\\\\\\\\\\\\\\\/kDcsy7A1e5k+WoVBdusj70t6CRoCizcbRdoDrOkk3WFzOGLglxraCYhV+olj3KLgExEio8hQ+Ex1gcHDIhtyDanSQioL8bNpBRYnTZtnhYRNOBUp4sXg\\\\\\\\\\\\\\\/iy\\\\\\\\\\\\\\\/xPH+yD2SFvvfiaaH00OvtIAI2DvIdQoNA0I7CapjmnlyFYUct9umNSlWvVrmAm\\\\\\\\\\\\\\\/OTSdHMmhvpDu\\\\\\\\\\\\\\\/LhlMJO2zIM65wt7GtW9mgNR3eyaTRuHygpXflbmXOTa2KQkHSv0Bfu68aP\\\\\\\\\\\\\\\/5JXy\\\\\\\\\\\\\\\/dX89\\\\\\\\\\\\\\\/7DOXNCQSPDVbDxEm7oaIQiXdS1\\\\\\\\\\\\\\\/924SLvUJ7cG53IHXIlU4W9e\\\\\\\\\\\\\\\/Ibbm9g92E\\\\\\\\\\\\\\\/6cYp5iIybD43dHPyl1sUTR1JzVw55ghHPHdXThphSb+C2hr04d5qgEBRad4TULdsPuJcEuzz5j34Ga5jNILIVmcbfNxEFEUgaWu4bPiEUh0n\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/5w5vsWuDUqRbClzVpBDjlJAuYMqnGycpKk7JkjqeoU1iCjwS04CQa2MAyadr1Z1oJt1IRkE+a6fHZf5y6CQe0AHtNKeEcwS5L6BhH2DtRgxECsDmXZZpKZTeGVzLwaFFKB+wbdaX+D9CtzfMUmFyNRLb6v1X2vHrm\\\\\\\\\\\\\\\/LF4QiYclxZ0DoWyvRsTmvzw5MOC7iuXAbChaQTHnpO\\\\\\\\\\\\\\\/icCa03k6lYGHOmnfJdszi7EhZcYa0ceWz654ldrRwRp0BXuHuV6yaUEFgcz3yGRFxJi6FSXXyRihKqPr1Z0z\\\\\\\\\\\\\\\/9holESmwN3HGTafP8SeAVlHW2JO7iRCfDO\\\\\\\\\\\\\\\/IFTUrvUD2D3gqd0hgTdf7r5xlwDdHH5V966VwftfLSLf901IxgL36i61MQ9Jbag6ZNYq5DvMOwB0NwlavypUbQyOkxqBKuRb8VyN3JwDYsDz8jzzaAfpaT49dFC9LJqfOOhBoeYSAd3R66N5J99ObsGyBg0D+o8P2JmEbU3yGDaWKvkvU8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Ie5O5HJgVspQEVCWFx0+aw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022b055a4744f7708dedfe6852ada7f0640f75a51a8a86e03570e9bb51745440b08\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1564.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1564.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1406\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1406\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1406\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}